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Türkiye'de Kronik Hepatitin Özellikleri ve Etyolojik Faktörler

Year 1976, Volume: 29 Issue: 3, 613 - 622, 30.09.1976

Zafer Paykoç

Abstract

A. Ü. Tıp Fakültesi Gastroenteroloji Kliniğinde takip edilen kronik hepatit vak'a gurubu incelenerek Türkiye'de kronik hepatit etyolojisine yaklaşımda bulunulmuştur.
40 Kronik hepatit vak'asında yapılan klinik, serolojik ve histopatolojik inceleme ile 9 kronik persistant hepatit, kronik aktiv hepatit örneği saptanmıştır.
Vak'alarımızın tümünde HB ag positivliği % 47 bulundu bu oran kronik aktiv hepatitde % 51.0 kronik persistant hepa-
UGUR KANDÌLCÌ — ÖZDEN UZUNALÏMOGLU ZAFER PAYKOÇ
titde % 33.3 dür. Kronik aktiv hepatit vak'alarm yalnu 3 tanesi sistemik belirtileri ile Lupoid hepatit tipindedir. Bu bulgular ile memleketimizde Kronik hepatit vak'alarmm hemen yarlS1 HB ag (+) , sinsi seyirli sistemik belirtileri bulunmwan ve laboratuvarda orta derecede transmmaz) globilin yüksekliži ile karakterize vak'alar oldužunu göstermektedir. Etyolojide sorumlu ilâçlar, alkol, otoimmun mekanizma ile olusan kronik aktiv hepatit örnežinin memleketimizde oldukça nadir oldugu kamslndasnz.

Keywords

hbv akut hepatit kronik hepatit

Ethical Statement

-

Supporting Institution

Ankara University Faculty of Medicine

Project Number

-

References

  • 1 — Groote J. D, Desmet V.J, Popper H, Schener P. A.A Classification of chronic hepatitis Lancet Il: 626,1968
  • 2 — Popper H, Theproblemofhepatitis. Amer. J. Gastroenterology 55: 355, 1971 3 — Wright R. Chronic hepatitis. Brit. Med. Bull. 28; 120,197?
  • 13 — Mac Kay Ir, Weiden S, Hasker J. Autoimmun hepatitis. Ann NY Acad. sci 124 : 767, 1965
  • 14 — Popper H, and MacKey IR: Ralation between Australia antigen and au- 15 — Soloway RD, Summershlll WHJ, Bagentoss AH ve ark. «Lupoid» hepatitis non entity In the spectrum of active chronic disease Gastroenterology 63: 458, 1972.
  • 16 — MacKay IR, Taft LI cowling DC Lupocolhepatit is Lancet 2: 1323, 1956
  • 17 — Paykoç Z,• Uzunalimožlu Ö. Alptuna E ve ark, Hepatitis B (Avustralya) antijeni : Il Kronik karacižer hastallklarmda Ank. Üniv. TIP Fak. Mec. 27: 717, 1974
  • 18 — Hadziyanlnls SJ, Merlkas GE, Afroudakls A. Hepatitis associated antigen in chrornc liver chsease Lancet Il, 100, 1970
  • 19 — Reed WD, Stern RD. Eddleston ALW Williams R Detection of hepatitis B antigen by radioimmunoassay in chrom liver cliseose and hepatocelluler carcmoma In Great Britain Lancet 11, 690, 1973
  • 20 — Cullinan ER, King RC, Rivers JS theproglosis of Infective hepatitis Brit Med. J. 1: 1315, 1958
  • 21 — Zieve L, Hill E, Nesbitt S, Zieve B the incidence of residuals of viral hepatitis Gastroenterology 25: 495, 1953.
  • 22 — Chuttam HK, Sldhu AS, Gupta Ill Ramanligaswani V. Follow - up study of cases from the Delhi epidemic of Infections hepatitis Bri. Med. J. 11.676 1966
  • 23 — Dudley F.T, O'shea M.J, A.J. dukiewiez Ave Sherlock S. Serum autoantibodies and immunglobillus in hepatitis - associated autlgen (HAAJ - posi- tive and negative liver disease Gut 14: 360, 1973.
  • 24 — Bolun T.D. Davis E.A. ve Liddelow A b Liver diseare and cell wediated Immunity Inhepotitis associated (HA A) Corriers. Gut 14. 365, 1973.
  • 25 Mackay IR. The cauceptof autommune luver disease. Bull. N.Y. Acad. Med. 52, 453, 1976.
  • 4 — Mac Kay. L I. Chronic hepatitis Can. Med. Ass J. 106 : 518, 1972
  • 5 Thaler H, Nature] history of chronic hepatitis. In the liver and its disease. Intercontinental Med Book Pub New York 1974, S. 207 - 209 6 — Mac Kay, I R Morris J. P. Association of outoimmune active chronichepatitis with HI -8 Lancet 2: 793,1971
  • 7 — Alptuna E, TürkvanM, Koca Y, Uzunalimožlu Ö. Konrimmunelektroroforezme todu ile Avustralya antijeni arastmlmasmda yenibirtampon solusyon denenmesi Ank. Üniv. TIP Fak. Mec. 25: 601,1972
  • 8 — Sherlock S. Cronic hepatitis Gut. 15: 581,1974
  • 9 — Baggenstoss A. H, Summershill W.H.J. and Ammon H.V. The morpho- logy of chronic hepatitis the liver and its disease. intercontinental med. Book Pub. Newyor 1974, I. 189 - 206.
  • 10 — Summerskill WHJ. Chronic active liver disease reexamined, prognosis hopeful Gastroenterology 66: 450, 1974
  • 11 — Becker M D - Schener PJ? Baptista A, et 01. Prognosis of chronic persistant hepatitis Lancet I: 53, 1970.
  • 12 — Uzunalimožlu O. Kronik hepatit ve Avustralya antijeni Ak. Üni. TIP Fak.. mec. 25: sup No: 61, 1972.

Characteristics And Etiological Factors Of Chronic Hepatitis In Turkey

Year 1976, Volume: 29 Issue: 3, 613 - 622, 30.09.1976

Zafer Paykoç

Abstract

40 patients with chronic hepatitis were studied clinically, and histopatologically. These cases were diided into two groups. 9 of these cases proved to be persistant hepatitis, 31 of these to be chronic active hepatitis.
In 47 % of he chronic hepatitis cases HB Ag was positiv. This relation was found 51 percent in the patients with chronic active hepatitis and 33 percent in chronic persistant hepatitis only 3 of all the chronic active hepatitis cases were lupold„ he patitis type.
The results suggest thet in our cauntry aetiologically alc Alcohol hol, drugs, or autoimmun mechanisms is quite rare in pathogenesis of chronic hepatitis.

Keywords

HBV CHRONIC HEPATITIS acute hepatitis

Ethical Statement

-

Supporting Institution

Ankara University Faculty of Medicine

Project Number

-

Thanks

-

References

  • 1 — Groote J. D, Desmet V.J, Popper H, Schener P. A.A Classification of chronic hepatitis Lancet Il: 626,1968
  • 2 — Popper H, Theproblemofhepatitis. Amer. J. Gastroenterology 55: 355, 1971 3 — Wright R. Chronic hepatitis. Brit. Med. Bull. 28; 120,197?
  • 13 — Mac Kay Ir, Weiden S, Hasker J. Autoimmun hepatitis. Ann NY Acad. sci 124 : 767, 1965
  • 14 — Popper H, and MacKey IR: Ralation between Australia antigen and au- 15 — Soloway RD, Summershlll WHJ, Bagentoss AH ve ark. «Lupoid» hepatitis non entity In the spectrum of active chronic disease Gastroenterology 63: 458, 1972.
  • 16 — MacKay IR, Taft LI cowling DC Lupocolhepatit is Lancet 2: 1323, 1956
  • 17 — Paykoç Z,• Uzunalimožlu Ö. Alptuna E ve ark, Hepatitis B (Avustralya) antijeni : Il Kronik karacižer hastallklarmda Ank. Üniv. TIP Fak. Mec. 27: 717, 1974
  • 18 — Hadziyanlnls SJ, Merlkas GE, Afroudakls A. Hepatitis associated antigen in chrornc liver chsease Lancet Il, 100, 1970
  • 19 — Reed WD, Stern RD. Eddleston ALW Williams R Detection of hepatitis B antigen by radioimmunoassay in chrom liver cliseose and hepatocelluler carcmoma In Great Britain Lancet 11, 690, 1973
  • 20 — Cullinan ER, King RC, Rivers JS theproglosis of Infective hepatitis Brit Med. J. 1: 1315, 1958
  • 21 — Zieve L, Hill E, Nesbitt S, Zieve B the incidence of residuals of viral hepatitis Gastroenterology 25: 495, 1953.
  • 22 — Chuttam HK, Sldhu AS, Gupta Ill Ramanligaswani V. Follow - up study of cases from the Delhi epidemic of Infections hepatitis Bri. Med. J. 11.676 1966
  • 23 — Dudley F.T, O'shea M.J, A.J. dukiewiez Ave Sherlock S. Serum autoantibodies and immunglobillus in hepatitis - associated autlgen (HAAJ - posi- tive and negative liver disease Gut 14: 360, 1973.
  • 24 — Bolun T.D. Davis E.A. ve Liddelow A b Liver diseare and cell wediated Immunity Inhepotitis associated (HA A) Corriers. Gut 14. 365, 1973.
  • 25 Mackay IR. The cauceptof autommune luver disease. Bull. N.Y. Acad. Med. 52, 453, 1976.
  • 4 — Mac Kay. L I. Chronic hepatitis Can. Med. Ass J. 106 : 518, 1972
  • 5 Thaler H, Nature] history of chronic hepatitis. In the liver and its disease. Intercontinental Med Book Pub New York 1974, S. 207 - 209 6 — Mac Kay, I R Morris J. P. Association of outoimmune active chronichepatitis with HI -8 Lancet 2: 793,1971
  • 7 — Alptuna E, TürkvanM, Koca Y, Uzunalimožlu Ö. Konrimmunelektroroforezme todu ile Avustralya antijeni arastmlmasmda yenibirtampon solusyon denenmesi Ank. Üniv. TIP Fak. Mec. 25: 601,1972
  • 8 — Sherlock S. Cronic hepatitis Gut. 15: 581,1974
  • 9 — Baggenstoss A. H, Summershill W.H.J. and Ammon H.V. The morpho- logy of chronic hepatitis the liver and its disease. intercontinental med. Book Pub. Newyor 1974, I. 189 - 206.
  • 10 — Summerskill WHJ. Chronic active liver disease reexamined, prognosis hopeful Gastroenterology 66: 450, 1974
  • 11 — Becker M D - Schener PJ? Baptista A, et 01. Prognosis of chronic persistant hepatitis Lancet I: 53, 1970.
  • 12 — Uzunalimožlu O. Kronik hepatit ve Avustralya antijeni Ak. Üni. TIP Fak.. mec. 25: sup No: 61, 1972.
There are 22 citations in total.

Details

Primary Language Turkish
Subjects Gastroenterology Surgery, Gastroenterology and Hepatology
Journal Section Articles
Authors

Zafer Paykoç This is me

Project Number -
Publication Date September 30, 1976
Published in Issue Year 1976 Volume: 29 Issue: 3

Cite

APA Paykoç, Z. (1976). Türkiye’de Kronik Hepatitin Özellikleri ve Etyolojik Faktörler. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 29(3), 613-622.
AMA Paykoç Z. Türkiye’de Kronik Hepatitin Özellikleri ve Etyolojik Faktörler. Ankara Üniversitesi Tıp Fakültesi Mecmuası. September 1976;29(3):613-622.
Chicago Paykoç, Zafer. “Türkiye’de Kronik Hepatitin Özellikleri Ve Etyolojik Faktörler”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 29, no. 3 (September 1976): 613-22.
EndNote Paykoç Z (September 1, 1976) Türkiye’de Kronik Hepatitin Özellikleri ve Etyolojik Faktörler. Ankara Üniversitesi Tıp Fakültesi Mecmuası 29 3 613–622.
IEEE Z. Paykoç, “Türkiye’de Kronik Hepatitin Özellikleri ve Etyolojik Faktörler”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 29, no. 3, pp. 613–622, 1976.
ISNAD Paykoç, Zafer. “Türkiye’de Kronik Hepatitin Özellikleri Ve Etyolojik Faktörler”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 29/3 (September1976), 613-622.
JAMA Paykoç Z. Türkiye’de Kronik Hepatitin Özellikleri ve Etyolojik Faktörler. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1976;29:613–622.
MLA Paykoç, Zafer. “Türkiye’de Kronik Hepatitin Özellikleri Ve Etyolojik Faktörler”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 29, no. 3, 1976, pp. 613-22.
Vancouver Paykoç Z. Türkiye’de Kronik Hepatitin Özellikleri ve Etyolojik Faktörler. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1976;29(3):613-22.