New Views On The Biotransformation Of Anesthetic Drugs And Their Application

Year 1975, Volume: 28 Issue: 1-2, 449 - 458, 30.06.1975

Refik Paykoç

Abstract

Unusual reaction to anesthetic agents is not a rare entity in Practice of Anesthesia some of the clinically important reactions include Halothane Hepatotoxicity, Methoxyflurane Nefrotoxicity and the malignant Hyperthermia.
In this article new concepts of anesthetic biotransformation and its application to clinical practice is explained. For the time being, the effects of metabolism on clinical toxicity of genera] anesthetic agents seems like a valid hypothesis.

Keywords

ANESTHETIC DRUGS , BIOTRANSFORMATION , ANESTHESIA

Supporting Institution

ankara university school of medicine

Anestezik İlaçların Biyotransformasyonu ve Uygulama Yönünden Yeni Görüşler

Abstract

Anestezi uygulamasında anestezik aianlara karsl anormal reaksiyonlarln görülmesi nadir dežildir. Bu reaksiyonlar araslnda klinik önemi olanlar halotan hepatotoksisitesi, methoxyflurane nefrotoksisitesi ve malign hipertermidir.
Bu makalede anestezik maddelerin biyotransformasyonunda yeni görüsler ve bunun klinik uygulamaya olan etkisi izah edilmege çall}llmaktadlr. Bugün için anestezik maddelere karsl görülen anormal reaksiyonlarln metabolik etki ile izahl geçerli bir hipotez gibi görülmektedir.

Keywords

ANESTEZİK İLAÇLAR , BİYOTRANSFORMASYON , ANESTEZİ

Supporting Institution

ankara üniversitesi tıp fakültesi

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