Spinal Meningothelial Meningioma in a Dog

Abstract

The objective of this study is to report clinical, MRI, surgical, and histological findings of spinal meningothelial meningioma in a dog. The study material was a 9 years old, spayed dog with a history of progressive nonambulatory tetraparesis. The dog had intact cranial and spinal reflexes and deep pain perception. Magnetic resonance images revealed a mass located at the left side C2-C3 level, hyperintense in T1W, isointense on T2W, and well contrast enhancing on postcontrast T1. The mass was microsurgically resected and sub-gross. The dog’s neurological status was improved at one week and survived for 15 months without signs of metastasis. Histological and histochemical workup revealed grade I, meningothelial meningioma. Surgical intervention for spinal meningioma can be suggested as the sole treatment in dogs.

Keywords

• Dog
• Meningotheliomatous Meningioma
• MRI
• Neurosurgery

References

1. Asano K, Kadosawa T, Mori T, et al (2005): Ventilatory failure and successful management for a dog with severe cervical meningioma. J Vet Med Sci, 67, 599–602.
2. Barresi V, Caffo M, Tuccari G (2016): Classification of human meningiomas: lights, shadows, and future perspectives. J Neurosci Res, 94, 1604-1612.
3. Besalti O, Caliskan M, Can P, et al (2016): Imaging and surgical outcomes of spinal tumors in 18 dogs and one cat. J Vet Sci, 17, 225-234.
4. Boomker J, Kloeck PE, Schaap D (1978): Meningioma in a dog. J S Afr Vet Assoc, 49, 133-135.
5. Fingeroth JM, Prata RG, Patnaik AK (1987): Spinal meningiomas in dogs: 13 cases (1972-1987). JAVMA, 191, 720-726.
6. Hasegawa D, Kobayashi M, Fujıta M, et al (2008): A meningioma with hyperintensity on T1-weighted images in a dog. J Vet Med Sci, 70, 615-617.
7. Higgins RJ, Bollen AW, Dickinson PJ, et al (2017): Tumors of the Nervous System. 864-869. In: DJ Meuten (Ed), Tumors in Domestic Animals. Wiley Blackwell, USA.
8. McDonnell JJ, Tidwell AS, Faissler D, et al (2005): Magnetic resonance imaging features of cervical spinal cord meningiomas. Vet Radiol Ultrasound, 46, 368–374.

9. Montoliu P, Anor S, Vidal E, et al (2006): Histological and Immunohistochemical Study of 30 Cases of Canine Meningioma. J Comp Pathol, 135, 200-207.
10. Ober CA, Chai O, Milgram J, et al (2018): Meningioma in cervical spinal cord segment 6 of a dog–a case report. Acta Vet Brno, 87, 225-229.
11. Petersem SA, Sturges BK, Dickinson PJ, et al (2008): Canine intraspinal meningiomas: imaging features, histopathologic classification, and long‐term outcome in 34 dogs. J Vet Intern Med, 22, 946-953.
12. Ramos-Vara JA, Borst LB (2017): Immunohistochemistry Fundamentals and Applications in Oncology. 65-85. In: DJ Meuten (Ed), Tumors in Domestic Animals. Wiley Blackwell, USA.
13. Roberto JL, Fuente CDL, Pumarola M, et al (2013): Spinal meningiomas in dogs: description of 8 cases including a novel radiological and histopathological presentation. Can Vet J, 54, 948-954.
14. Sessums K, Mariani C (2009): Intracranial meningioma in dogs and cats: a comparative review. Compend Contin Educ Vet, 31, 330-339.
15. Sturges BK, Dickinson PJ, Bollen AW, et al (2008): Magnetic resonance imaging and histological classification of intracranial meningiomas in 112 dogs. J Vet Intern Med, 22, 586-595.
16. Tommaso B, Bernardini M, Cherubini G, et al (2017): Texture analysis of magnetic resonance images to predict the histologic grade of meningiomas in dogs. Am J Vet Res, 78, 1156-1162.