Levels of medium-molecular-weight peptides in the cerebral cortex of rats of different ages and nervous system types under high-protein and protein-free diets

Samira Ibrahimova

doi:10.33988/auvfd.1627124

Levels of medium-molecular-weight peptides in the cerebral cortex of rats of different ages and nervous system types under high-protein and protein-free diets

Abstract

The aim of this study was to investigate the effects of high-protein and protein-free diets on the levels of medium-molecular-weight peptides (MMPs) in specific brain regions of rats of different ages and nervous system types. The animals were divided into stress-resistant and stress-sensitive groups. A control was selected from each group and maintained under vivarium conditions. The experimental animals were divided into two subgroups and were fed a special diet for periods of 10, 20, or 30 days. In the first subgroup, the dietary components were completely preserved (protein-based diet), whereas in the second subgroup casein was excluded from the diet (protein-free diet). At the end of the specified feeding periods, levels of MMPs in tissue homogenates of the bilateral limbic and orbital cortices (left and right hemispheres) of control and experimental rats were determined. In 3-month-old animals, MMP levels increased on both high-protein and protein-free diets. In contrast, in 12-month-old animals, MMP levels decreased under both conditions. Also, with both protein-containing and protein-free nutrition, interhemispheric asymmetry was observed in the MMPs content of the limbic and orbital cortices of the left and right hemispheres in 3- and 12-month-old stress-resistant and stress-sensitive animals.

Keywords

References

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Details

Primary Language

English

Subjects

Veterinary Sciences (Other)

Journal Section

Research Article

Authors

Samira Ibrahimova ^*
0000-0001-7548-6170
Azerbaijan

Early Pub Date

December 2, 2025

Publication Date

January 1, 2026

Submission Date

February 5, 2025

Acceptance Date

November 9, 2025

Published in Issue

Year 2026 Volume: 73 Number: 1

DOI

https://doi.org/10.33988/auvfd.1627124

IZ

https://izlik.org/JA82YT95BL

Cite

RIS / Bibtex

APA

Ibrahimova, S. (2026). Levels of medium-molecular-weight peptides in the cerebral cortex of rats of different ages and nervous system types under high-protein and protein-free diets. Ankara Üniversitesi Veteriner Fakültesi Dergisi, 73(1), 93-101. https://doi.org/10.33988/auvfd.1627124

AMA

1.Ibrahimova S. Levels of medium-molecular-weight peptides in the cerebral cortex of rats of different ages and nervous system types under high-protein and protein-free diets. Ankara Univ Vet Fak Derg. 2026;73(1):93-101. doi:10.33988/auvfd.1627124

Chicago

Ibrahimova, Samira. 2026. “Levels of Medium-Molecular-Weight Peptides in the Cerebral Cortex of Rats of Different Ages and Nervous System Types under High-Protein and Protein-Free Diets”. Ankara Üniversitesi Veteriner Fakültesi Dergisi 73 (1): 93-101. https://doi.org/10.33988/auvfd.1627124.

EndNote

Ibrahimova S (January 1, 2026) Levels of medium-molecular-weight peptides in the cerebral cortex of rats of different ages and nervous system types under high-protein and protein-free diets. Ankara Üniversitesi Veteriner Fakültesi Dergisi 73 1 93–101.

IEEE

[1]S. Ibrahimova, “Levels of medium-molecular-weight peptides in the cerebral cortex of rats of different ages and nervous system types under high-protein and protein-free diets”, Ankara Univ Vet Fak Derg, vol. 73, no. 1, pp. 93–101, Jan. 2026, doi: 10.33988/auvfd.1627124.

ISNAD

Ibrahimova, Samira. “Levels of Medium-Molecular-Weight Peptides in the Cerebral Cortex of Rats of Different Ages and Nervous System Types under High-Protein and Protein-Free Diets”. Ankara Üniversitesi Veteriner Fakültesi Dergisi 73/1 (January 1, 2026): 93-101. https://doi.org/10.33988/auvfd.1627124.

JAMA

1.Ibrahimova S. Levels of medium-molecular-weight peptides in the cerebral cortex of rats of different ages and nervous system types under high-protein and protein-free diets. Ankara Univ Vet Fak Derg. 2026;73:93–101.

MLA

Ibrahimova, Samira. “Levels of Medium-Molecular-Weight Peptides in the Cerebral Cortex of Rats of Different Ages and Nervous System Types under High-Protein and Protein-Free Diets”. Ankara Üniversitesi Veteriner Fakültesi Dergisi, vol. 73, no. 1, Jan. 2026, pp. 93-101, doi:10.33988/auvfd.1627124.

Vancouver

1.Samira Ibrahimova. Levels of medium-molecular-weight peptides in the cerebral cortex of rats of different ages and nervous system types under high-protein and protein-free diets. Ankara Univ Vet Fak Derg. 2026 Jan. 1;73(1):93-101. doi:10.33988/auvfd.1627124