Conjunctival leiomyosarcoma in a dog

Abstract

In the case, leiomyosarcoma is described pathomorphologically in conjuctiva of a 5 years old male dog. Macroscopically, the mass were weight of 14 g, 4x4x3 cm in diameter, grayish-white and firm consistency. On cut section, there were generally grayish white color but included haemorrhagic foci in some areas. Histologically, anaplastic muscle cells, were seen ovoid or spindle shape, had architecture of bundles in different way or whorles. The cells were differentiated by staining red in Masson’s trichrome method. In addition, haemorrhagic areas were get along with these cells

Keywords

• Conjunctiva
• dog
• leiomyosarcoma

Bir köpekte konjunktival leiomyosarkom

Abstract

Bu olguda, sol gözün alt kapağında şişlik şikayeti bulunan 5 yaşlı, erkek bir köpeğin konjunktivasından alınan biyopsi örneğinde leiomyosarkom olgusu patomorfolojik olarak tanımlandı. Tümöral kitle makroskobik olarak, 14 gr ağırlığında, 4x4x3 cm boyutlarında ve elastik kıvamlıydı. Kesit yüzü ise boz-beyaz renkte ve yer yer küçük kanama alanları mevcuttu. Histolojik olarak ise çeşitli yönlere kollar veren bantlar veya girdaplar yapmış, Masson’un trikrom boyası ile kırmızı renkte boyanan, oval veya uzunca görünüşlü anaplazik kas hücrelerinden oluşan yapılara kanama alanlarının eşlik ettiği görüldü

Keywords

• Köpek
• konjunktiva
• leiomyosarkom

References

1. Cohen M, Post GS, Wright JC (2003): Gastrointestinal leiomyosarcoma in 14 dogs. J Vet Intern Med, 17, 107-110.
2. Cooper BJ, Valentine BA (2002): Tumors of Muscle. In: DJ Meuton, (ed), Tumors in Domestic Animals. 4 th ed. pp. 319-363. Iowa State Press, Iowa.
3. Hayden DW, Klausner JS, Waters DJ (1999): Prostatic leiomyosarcoma in a dog. J Vet Diagn Invest, 11, 283-286.
4. Kapatkin AS, Mullen HS, Matthiesen DT, Patnaik AK (1992): Leiomyosarcoma in dogs: 44 cases (1983-1988). J Am Vet Med Assoc, 201, 1077-1079.
5. McCowan C, Stanley RG (2004): Pigmented squamous cell carcinoma of the conjunctiva of a horse. Vet Ophthalmol, 7, 421-423.
6. Moore CP, Collins BK, Linton LL, Collier LL (2000): Conjunctival malignant melanoma in a horse. Vet Ophthalmol, 3, 201-206.
7. Multari D, Vascellari M, Mutinelli F (2002): Hemangiosarcoma of the third eyelid in a cat. Vet Ophthalmol, 5, 273-276.
8. Murphy CJ, Bellhorn RW, Buyukmihci NC (1989): Bilateral conjunctival masses in two dogs. J Am Vet Med Assoc, 195, 225-228.

9. Penninck DG (1998): Characterization of gastrointestinal tumors. Vet Clin North Am Small Anim Pract, 28, 777-797.
10. Pirie CG, Knollinger AM, Thomas CB, Dubielzig RR (2006): hemangiosarcoma: a retrospective evaluation of 108 cases (1989-2004). Vet Ophthalmol, 9, 215-226.
11. Reis-Filho JS, Gonçalves C, Gärtner F (2003): Rectal
12. leiomyosarcoma in a dog and review of gastrointestinal stromal tumours. Vet Rec, 153, 215-217.
13. Sato T, Aoki K, Shibuya H, Machida T, Watari T (2003): Leiomyosarcoma of the kidney in a Dog. J Vet Med, 50, 366-369.