The effect of tibial dyschondroplasia on metabolic parameters in broiler chickens

Abstract

Tibial dyschondroplasia (TD) deteriorates the welfare of broiler chickens and causes economic loss. The present study was aimed at the investigation of the effect of TD on metabolic parameters and the demonstration of the aetiology of this disorder. For this purpose, blood serum mineral, lipid, protein, glucose, uric acid and enzyme levels, and histopathological alterations in the tissues of the tibiotarsal joint were determined. Ten broiler chickens suffering from TD and 10 healthy broiler chickens, all which were of the Ross 308 breed, constituted the material of the study. Analyses showed that calcium, phosphorus and free fatty acid blood serum levels were lower, whilst triglyceride, cholesterol, low density lipoproteins (LDL), very low density lipoproteins (VLDL) rates and uric acid and creatinine levels were higher in animals suffering from tibial dyschondroplasia, compared to healthy animals (P<0.05). No statistically significant difference existed between the glucose and amylase levels and alanine aminotransferase (ALT), aspartate aminotransferase (AST), γ-glutamyltransferase (GGT), and alkaline phosphatase (ALP), activities of broilers diagnosed with tibial dyschondroplasia and healthy broilers. The histopathological examination of the tissues of the tibiotarsal joint of the animals diagnosed with TD revealed degenerative alterations characterized by the dominance of hypertrophy and the lack of urate crystals and calcification in chondrocytes. In animals with TD, calcium and phosphorus blood serum levels were low, whilst the lipid profile and amount of uric acid were high. On the other hand, ALP enzyme activity was determined not to display any alteration

Keywords

• Broiler
• metabolic parameter
• tibial dyschondroplasia

Etçi piliçlerde tibial diskondoplazinin metabolik parametrelere etkisi

Abstract

Tibial diskondoplazi (TD) piliçlerin refahını bozmakta ve ekonomik kayıplara neden olmaktadır. Bu çalışma TD’nin metabolik parametrelere etkisini ve etiyolojisini belirlemek amacıyla yapılmıştır. Bu nedenle hayvanların kan serumlarında mineral, lipit, protein, glikoz, ürik asit ve enzim değerleri ve tibiotarsal eklem dokusundaki histopatolojik değişimler tespit edilmiştir. Araştırmada10 adet TD’li ve 10 adet sağlıklı broiler (Ross 308) kullanılmıştır. Tibial diskondoplazili hayvanların kan serumlarındaki kalsiyum, fosfor seviyesi ve serbest yağ asitleri oranı sağlıklı hayvanlardan düşük; tigliserit, kolesterol, düşük yoğunluklu lipoprotein (LDL), çok düşük yoğunluklu lipoprotein (VLDL) oranları, ürik asit ve kreatinin miktarları ise yüksek bulunmuştur (P<0.05). Tibial diskondoplazili ve sağlıklı broilerin glikoz ve amilaz seviyeleri ile alanin aminotransferaz (ALT), aspartat aminotransferaz (AST), γglutamyltransferaz (GGT), ve alkalin fosfataz (ALP), aktiviteleri arasında ise istatistiksel farklılık tespit edilmemiştir. Araştırmada TD’li hayvanların tibiotarsal eklem dokusunun histopatolojik incelenmesinde dejeneratif değişiklikler, kondrositlerde hipertrofinin baskın olduğu, ürat kristalleri ve kalsifikasyonun ise olmadığı tespit edildi. Tibial diskondoplazili hayvanların kan serumlarında kalsiyum ve fosfor seviyelerinin düşük, lipit profilinin ve ürik asit miktarının yüksek, ALP enzim aktivitesinin ise değişmediği belirlenmiştir

Keywords

• Broyler
• metabolik parameter
• tibiyal diskondroplazi

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