The volume fraction method for the evaluation of kidney: A stereological study

Abstract

It is known that the kidney size is related to body height, body surface area and body weight. In the present study we propose the volume fraction approach of stereological methods that eliminate the effects of body size over the quantitative evaluation of cortex, medulla and pelvis of kidney. Kidneys were removed from 20 Kivircik sheeps and their volumes were measured using the Archimedean principle. The total volume and volume of its components and the volume fraction of cortex, medulla and the pelvis were estimated stereologically. The mean kidney volumes were 61.3±12.7cm3 and 59.7±12.8cm3, using the Archimedean and the Cavalieri principles, respectively. The obtained values were not found to be significantly different (p>0.05). The kidney was composed of 69.7±3.0% cortex, 27.1±2.9% medulla and 3.2±0.7% pelvis. Our results show that the stereological method applied in this study provides unbiased data about the volumetric characteristics of kidney and can be used on physical section of the evaluation of the volume and volume fractions of kidney and its subcomponents

Keywords

• Cavalieri principle
• renal cortex
• renal medulla
• renal pelvis
• stereology

Böbrek değerlendirmesi için hacimsel oran metodu: Stereolojik çalışma

Abstract

Böbrek büyüklüğünün, vücut yüksekliği, vücut yüzey alanı ve vücut ağırlığı ile ilişkili olduğu bilinmektedir. Yapılan bu çalışmada, korteks, medulla ve böbrek pelvisinin rakamsal değerlendirilmesi üzerinde vücut büyüklüğünün etkilerini elimine etmek amacı ile, stereolojik metodlardan hacimsel oran yaklaşımı kullanılmıştır. Materyal olarak 20 adet Kıvırcık koyunundan elde edilen böbreklerin hacmi Arşimed prensibi kullanılarak ölçülmüştür. Ayrıca bu böbreklerin toplam hacmi ve korteks, medulla ve pelvis bölümlerinin hacmi stereolojik olarak tahmin edilmiştir. Arşimed ve Cavalier metodları kullanılarak elde edilen ortalama böbrek hacimleri sırası ile, 61.3±12.7 cm3 ve 59.7±12.8 cm3 olarak ölçülmüştür. Elde edilen veriler istatistiki olarak önemli bulunmamıştır (p>0,05). Böbrek, %69.7±3.0 korteks, %27.1±2.9 medulla ve %3.2±0.7 pelvis’den oluşmaktadır. Sonuçlarımız gösterir ki, bu çalışmada kullanılan stereolojik metodlar, böbreğin hacimsel karakteristikleri hakkında ön yargısız bilgi sağlar ve böbrek hacmi, hacimsel oranları ve alt bölümlerinin değerlendirilmesinde kullanılabilir

Keywords

• Cavalier prensibi
• cortex renalis
• medulla renalis
• pelvis renalis
• stereoloji

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