Changes in plasma levels of vitamin A and β-carotene in dogs with the nervous form of canine distemper

Abstract

In this study, changes in plasma vitamin A and β-carotene levels were investigated in dogs with the nervous form of canine distemper virus infection. Totally 20 dogs were used in study. Ten dogs with clinically showed the distemper disorders and this diagnosis were strengthen with immunohistochemistry were used as trial group. Ten healthy dogs with no clinical signs were used as control group. Plasma vitamin A concentrations in infected and healthy dogs 1.74±0.45 µg/dL and 2.26±0.53 µg/dL, respectively, β-carotene concentrations 12.32±2.43 µg/dL and 15.80±3.66 µg/dL were found. Plasma vitamin A and β-carotene levels in infected dogs with canine distemper virus were lower (p

Keywords

• Beta-carotene
• canine distemper
• dog
• plasma
• vitamin A

Köpek gençlik hastalığının sinirsel formundaki köpeklerin plazmasında vitamin A ve beta-karotin düzeylerindeki değişiklikler

Abstract

Bu çalışmada, köpek gençlik hastalığının (distemper) sinirsel formundaki köpeklerde plazma vitamin A ve beta-karotin (β-karotin) düzeylerindeki değişiklikler araştırıldı. Çalışmada toplam 20 adet köpek kullanıldı. Klinik muayene sonucunda köpek gençlik hastalığının sinirsel formu bulgularını gösteren ve histopatolojik ve immunohistokimyasal olarak sinirsel formda olduğu doğrulanan 10 adet köpek çalışmanın deneme grubunu oluşturdu. Herhangi bir klinik şikayeti olmayan sağlıklı 10 adet köpek ise kontrol grubuna alındı. Hastalıklı ve sağlıklı köpeklerde plazma vitamin A derişimleri sırası ile 1.74±0.45 µg/dL ve 2.26±0.53 µg/dL, β-karotin derişimleri ise 12.32±2.43 µg/dL ve 15.80±3.66 µg/dL bulundu. Köpek Gençlik Hastalığı virusu ile enfekte köpeklerin plazma vitamin A ve β-karotin düzeylerinin, sağlıklı köpeklere göre istatistik olarak daha düşük olduğu belirlendi (p

Keywords

• Beta-karotin
• köpek
• köpek gençlik hastalığı
• plazma
• vitamin A

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