HEP ATITIS CO NT AGIOSA CANIS

Abstract

The first cases in Turkey on H. c. c. were observed eight years ago in Ankara (I 5). Rcccntly the disease was again diagnosed on a four months and six months old setter dogs at post - mortem examination. Macroscopically, the visceral - and superficial lymph nodes were edematous, petechial hcmorrhages were present in the thymus, and mucous bran of the gaıı bladder. In addition the waıı of the gaıı bladder was ederr.atous. The spleen was moderately enlarged. The histologieal changes in the liver eonsisted of laeunar eetasia of the sinusoids, eentro - lobuler neerosis and intranudear indusion bodies in the liver eeııs, in the sinusoidal endothelial eeııs and Kupffer eeııs. Similar indusion bodies were found in the retieulo endothelial eeııs of the spleen, and lymph nodes; in the endothelial eeııs of the glomerular tufta, and in the eapillary endothclium of the brain. Perivaseular euffing and eoııection of neuroglia eells were noted partieularly in the meduııa oblongata. An attempt to transmitt the disease with liver suspension of this ease was made. Six puppies. were inoeulated subeutaneously, and intravenously (6). Three out of Six showed mieroseopieally typical lesions of H. e. e.

Keywords

• HEP
• ATITIS
• AGIOSA