SALIVARY GL AND VIRUS DISEASE IN GUINEA PIGS

Abstract

A virus disease of man and animals characterized by intranuclear and intracytoplasmic inelusion bodies in greatly hypertrophied ce lls primarily in the salivary glands and several organs was described many years ago. Strains of the vırus are species-specific, although the similarity of the morphologie changes they produce suggests that theyare biologically elosely relatcd. it is now well recognized that there exist in man, monkey and seveal rodents elosdy related viruses called cytomegaloviruse~, also salivary gland, submaxillary gland, and eytomegalic inelusion disease viruses which may lie dormant in the salivary glands, but are capable of causing fatal generalized infection in guinea pigs. A generalized blood dyscrasia, congenital defects such as microcephaly, cerebral cakification and hepatosplenomcgaly has been noted in infants by a number of investigators 3, ıı, 1 4 • Salivary gland disease İn a 4-week-old dog with degeneration of the ductal epithdium of the submaxyllary gland and eosinophilic intranuelear inelusion bodies was reported by Haberman at all 4. This is probbably the first recorded case of domesticated animals.

Keywords

• SALIVARY
• VIRUS
• PIGS

References

1. Ankara Üniversitesi- Ankara Üniversitesi Veteriner Fakültesi Dergisi