Case Report
BibTex RIS Cite

Treatment of giant benign fibrous histiocytoma of the forelimb in a Husky cross breed dog

Year 2026, Accepted Papers, 1 - 6
https://doi.org/10.33988/auvfd.1714194

Abstract

Presented case was an eight-year-old, male husky cross dog. According to the owner’s history, several months earlier, a drug had been injected into the left forelimb, after which localized swelling developed and progressed to an open wound. Although the wound was treated conservatively for an extended period, the swelling continued to enlarge. Clinical examination revealed a large-volume mass with a firm to slightly compressible consistency encompassing the entire left forelimb. Following medical therapy to control the underlying tissue infection, the entire mass was surgically excised. The resulting defect was closed using the remaining healthy skin. The dog achieved full recovery within 10 days postoperatively. Histopathological examination of the excised tissue confirmed a diagnosis of benign fibrous histiocytoma (BFH). BFH is a benign neoplasm composed of a mixture of fibroblastic and histiocytic cells. It most commonly occurs in the dermis but can also be found sporadically in soft tissues and parenchymal organs. In this case, a large, infected soft tissue tumor was successfully removed, and the wound healed without complications. To our knowledge, no prior reports have described a benign fibrous histiocytoma of such volume, with concurrent secondary infection and open wound formation, affecting an elderly dog’s limb. Therefore, this case is considered to contribute novel information to existing veterinary literature.

Ethical Statement

This study is not subject to the permission of HADYEK in accordance with the “Regulation on Working Procedures and Principles of Animal Experiments Ethics Committees” 8 (k). The data, information and documents presented in this article were obtained within the framework of academic and ethical rules. Also, all owners presenting cases to the faculty are requested to sign a consent form confirming their authorization for the use of data obtained from their animals for scientific and academic purposes. The relevant document has been uploaded to the system under the heading 'Ethics Committee Approval'.

Supporting Institution

This study wasn’t supported

References

  • 1Al-Jamali J, Gerlach UV, Zajonc H (2010): Benign fibrous histocytoma of the distal radius: a report of a case and a review of the literature. Hand Surg, 15, 127–129.
  • Bielamowicz S, Dauer MS, Chang B, et al (1995): Noncutaneous benign fibrous histiocytoma of the head and neck. Otolaryngol Head Neck Surg, 113,140–146.
  • Choi H, Kwon Y, Chang J, et al (2011): Undifferentiated Pleomorphic Sarcoma (Malignant Fibrous Histiocytoma) of the Head in a Dog. J Vet Med Sci, 73, 235-239.
  • Ertaş Ü, Büyükkurt MC, Çiçek Y (2003): Benign Fibrous Histiocytoma: Report of Case. J Contemp Dent Pract, 4, 74-79.
  • He S, Wen, Z (2024): A Clinical and histopathological analysis of 147 cases of dermatofibroma (benign fibrous histiocytoma). Adv Biosci Biotechnol, 15, 590-601.
  • Hendrick MJ (2017): Mesenchymal Tumors of the Skin and Soft Tissues. 142–175. In D. J. Meuten (Ed.), John Wiley & Sons, Iowa.
  • Heo, MS, Cho, HJ, Kwon, KJ, et al (2004): Benign fibrous histiocytoma in the mandible. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 97, 276-280.
  • Klijanienko, J, Caillaud, JM, Lagacé, R (2004). Fine‐needle aspiration of primary and recurrent benign fibrous histiocytoma: classic, aneurysmal, and myxoid variants. Diagn Cytopathol, 31, 387-391.
  • Mcpherson T (2004): Benign tumors of fibrous tissue and adipose tissue of the hand. Hand Ther, 18, 53–54.
  • Pessoa MCP, Maia FCI, Nardi AB, et al (2008): Aspectos clínicos, diagnóstico e tratamento dos histiocitomas caninos. Med Vet, 2, 42–53.
  • Prisse LA, Jayasooriya PR, Mendis BRRN, et al (2015): Benign fibrous histiocytomas of the oral mucosa: report on three cases and review of the literature. Dermatopathol, 2, 52–60.
  • Rapisarda G, Marino F, Ferrara G, et al (2004): Benign fibrous histiocytoma of prepuce in the mule. Reprod Domest Anim, 39, 61-63.
  • Reesink HL, Parente EJ, Sertich PL, Engiles JB (2009): Malignant fibrous histiocytoma of the mammary gland in a mare. Equine Vet Educ, 21, 467-472.
  • Skoulakis CE, Papadakis CE, Datseris GE, et al (2007): Subcutaneous benign fibrous histiocytoma of the cheek. Case report and review of the literature. Acta Otorhinolaryngol Ital, 27, 90–93.
  • Tanimoto T, Ohtsuki Y, Sonobe H, et al (1988): Malignant fibrous histiocytoma in the spleen of a pig. Vet Pathol, 25, 330-332.
  • Wouters EGH, Nimwegen SA, Ryan S, et al (2012): Skin and Subcutaneus Tumors 92-143 In: Kudnig ST, Séguin B, Carlson D (Eds), Veterinary Surgical Oncology. Wiley-Blackwell Pub, New Jersey.
  • Zibetti FL, Leão MS de, Trindade Júnior WP da, et al (2022): Histiocitoma em caninos e felinos: Revisão. Pubvet, 16, 1–5.
There are 17 citations in total.

Details

Primary Language English
Subjects Veterinary Surgery
Journal Section Case Report
Authors

Zeynep Bozkan Ünal 0000-0003-4233-6496

Ezgi Sude Aybak 0000-0001-5701-6159

S. Serap Birincioğlu This is me 0000-0001-5815-6508

Early Pub Date October 9, 2025
Publication Date October 16, 2025
Submission Date June 12, 2025
Acceptance Date September 30, 2025
Published in Issue Year 2026 Accepted Papers

Cite

APA Bozkan Ünal, Z., Aybak, E. S., & Birincioğlu, S. S. (2025). Treatment of giant benign fibrous histiocytoma of the forelimb in a Husky cross breed dog. Ankara Üniversitesi Veteriner Fakültesi Dergisi1-6. https://doi.org/10.33988/auvfd.1714194
AMA Bozkan Ünal Z, Aybak ES, Birincioğlu SS. Treatment of giant benign fibrous histiocytoma of the forelimb in a Husky cross breed dog. Ankara Univ Vet Fak Derg. Published online October 1, 2025:1-6. doi:10.33988/auvfd.1714194
Chicago Bozkan Ünal, Zeynep, Ezgi Sude Aybak, and S. Serap Birincioğlu. “Treatment of Giant Benign Fibrous Histiocytoma of the Forelimb in a Husky Cross Breed Dog”. Ankara Üniversitesi Veteriner Fakültesi Dergisi, October (October 2025), 1-6. https://doi.org/10.33988/auvfd.1714194.
EndNote Bozkan Ünal Z, Aybak ES, Birincioğlu SS (October 1, 2025) Treatment of giant benign fibrous histiocytoma of the forelimb in a Husky cross breed dog. Ankara Üniversitesi Veteriner Fakültesi Dergisi 1–6.
IEEE Z. Bozkan Ünal, E. S. Aybak, and S. S. Birincioğlu, “Treatment of giant benign fibrous histiocytoma of the forelimb in a Husky cross breed dog”, Ankara Univ Vet Fak Derg, pp. 1–6, October2025, doi: 10.33988/auvfd.1714194.
ISNAD Bozkan Ünal, Zeynep et al. “Treatment of Giant Benign Fibrous Histiocytoma of the Forelimb in a Husky Cross Breed Dog”. Ankara Üniversitesi Veteriner Fakültesi Dergisi. October2025. 1-6. https://doi.org/10.33988/auvfd.1714194.
JAMA Bozkan Ünal Z, Aybak ES, Birincioğlu SS. Treatment of giant benign fibrous histiocytoma of the forelimb in a Husky cross breed dog. Ankara Univ Vet Fak Derg. 2025;:1–6.
MLA Bozkan Ünal, Zeynep et al. “Treatment of Giant Benign Fibrous Histiocytoma of the Forelimb in a Husky Cross Breed Dog”. Ankara Üniversitesi Veteriner Fakültesi Dergisi, 2025, pp. 1-6, doi:10.33988/auvfd.1714194.
Vancouver Bozkan Ünal Z, Aybak ES, Birincioğlu SS. Treatment of giant benign fibrous histiocytoma of the forelimb in a Husky cross breed dog. Ankara Univ Vet Fak Derg. 2025:1-6.