Obsesif Kompulsif Bozukluk Tanılı Hastalarda Alkol Kullanım Bozukluğu ile İntihar Arasındaki İlişki

Yıl 2023, Cilt: 24 Sayı: 1, 53 - 60, 31.03.2023

Mahmut Onur Karaytuğ , Lut Tamam , Mehmet Emin Demirkol , Zeynep Namlı

https://doi.org/10.51982/bagimli.1148182

Öz

Amaç: Obsesif kompulsif bozukluk (OKB) tanılı hastalarda alkol kullanım bozukluğu ve özkıyım ilişkisine yönelik veriler sınırlıdır. Bu çalışmada OKB tanılı hastalarda alkol kullanım bozukluğu ile özkıyım arasında bir ilişki olabileceği hipotezimizi araştırmayı amaçladık.
Yöntem: Çalışmaya 92 OKB tanılı hasta alındı. Hastaların genel sosyodemografik ve klinik özellikleri değerlendirildi. OKB hastalarına Yale-Brown Obsesyon Kompulsiyon Ölçeği (Y-BOKÖ),Beck İntihar Düşüncesi öçeği uygulandı.
Bulgular: Örneklem 54 kadın, 38 erkekten oluşmaktadır. Hastaların geçmiş özkıyım girişim oranı %19,6 olarak tespit edilmiştir. 16 hastada Alkol Kullanım Bozukluğu eştanısı mevcuttu. Alkol kullanım Bozukluğu olan grupta sigara kullanım , ailede ruhsal hastalık öyküsü oranı ve Beck İntihar Düşüncesi Ölçek skoru anlamlı olarak daha yüksekti. Özkıyım girişimi olan grupta sigara kullanım, alkol kullanım oranı, ailede ruhsal hastalık öyküsü oranı ve Beck İntihar Düşüncesi Ölçek skoru anlamlı olarak daha yüksekti.
Sonuç: Bu çalışmanın sonucunda OKB tanılı hastalarda alkol kullanım bozukluğu eştanısının geçmişteki özkıyım düşünce ve girişimleri ile ilişkili olabildiği gösterilmiştir. Muayenede alkol kullanım bozukluğu saptadığımız OKB tanılı hastaların özkıyım açısından daha sık aralıklarla izlenmesi uygun olabilir. 

Anahtar Kelimeler

Obsesif Kompulsif Bozukluk, Alkol Kullanım Bozukluğu, Özkıyım, Obsessive compulsive disorder, alcohol use disorder, suicide

The Relationship Between Alcohol Use Disorder and Suicide in Patients with Obsessive Compulsive Disorder

Öz

Objective: Data on the relationship between alcohol use disorder and suicide in patients with obsessive-compulsive disorder (OCD) are limited. The aim of this study was to investigate our hypothesis that there may be a relationship between alcohol use disorder and suicide in patients with OCD.
Method: The study included 92 patients with OCD. General sociodemographic and clinical characteristics of the patients were evaluated. Yale-Brown Obsession Compulsion Scale (Y-BOCS) and Beck Suicidal Ideation Scale were administered to OCD patients.
Results: The sample consisted of 54 women and 38 men. The rate of past suicide attempts was 19.6%. 16 patients were comorbid with Alcohol Use Disorder. Smoking, family history of mental illness and Beck Suicidal Ideation Scale score were significantly higher in the group with Alcohol Use Disorder. Smoking, alcohol use, family history of mental illness and Beck Suicidal Ideation Scale score were significantly higher in the group with suicide attempt.
Conclusion: The results of this study showed that comorbid alcohol use disorder may be associated with past suicidal thoughts and attempts in patients with OCD. It may be appropriate to follow up OCD patients with alcohol use disorder more frequently in terms of suicide.

Anahtar Kelimeler

Obsessive compulsive disorder, alcohol use disorder, suicide

Kaynakça

• 1. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th edition, Washington: American Psychiatric Publishing, 2013.
• 2. Kugler BB, Lewin AB, Phares V, et al. Quality of life in obsessive-compulsive disorder: The role of mediating variables. Psychiatry Res 2013 ;206(1): 43–49.
• 3. Balci V, Sevincok L. Suicidal ideation in patients with obsessive-compulsive disorder. Psychiatry Res 2010 ;175(1–2): 104–108.
• 4. Sabancioğullari S, Avci D, Doğan S, et al.Psikiyatri kliniğinde yatan hastalarda intihar olasılığı ve etkileyen etkenler. Anadolu Psikiyatr Derg 2015 ;16(3): 164–172.
• 5. Hollander E, Greenwald S, Neville D, et al.Uncomplicated and Comorbid Obsessive-Compulsive Disorder in an Epidemiologic Sample. CNS Spectr 1998 ;3(S1): 10–18. 6. Özgüven HD. İntihar davranışı riskinin değerlendirilmesi. Turkiye Klinikleri J Psychiatry-Special Topics 2008; 1: 8-14.
• 7. Torres AR, Ramos-Cerqueira, ATA, Ferrão YA, et al.Suicidality in obsessive-compulsive disorder: Prevalence and relation to symptom dimensions and comorbid conditions. Journal of Clinical Psychiatry 2011; 72(1): 203-214.
• 8. Prakash Kamath DPM, Reddy Y, Kandavel T. Suicidal behavior in obsessive-compulsive disorder. J Clin Psychiatry 2007; 68(11): 1741-1750.
• 9. Alonso P, Segalàs C, Real E, et al. Suicide in patients treated for obsessive-compulsive disorder: A prospective follow-up study. J Affect Disord 2010; 124(3):300–308.
• 10. World Health Organization. Global status report on alcohol and health. World Health Organization 2006.
• 11. Lopez AD, Mathers CD, Ezzati M, et al.Measuring the Global Burden of Disease and Risk Factors, 1990–2001 Global Burden of Disease and Risk Factors 2006; 1: 1-14.
• 12. World Health Organization. Global status report on alcohol and health 2018. World Health Organization 2019.
• 13. Suzuki K, Muramatsu T, Takeda A, Shirakura K. Co-occurrence of obsessive-compulsive personality traits in young and middle-aged Japanese alcohol-dependent men. Alcohol Clin Exp Res 2002; 26(8): 1223–1227.
• 14. Anton RF, Moak DH, Latham PK. The obsessive compulsive drinking scale: A new method of assessing outcome in alcoholism treatment studies. Arch Gen Psychiatry 1996 ;53(3): 225–231.
• 15. McKeehan MB, Martin D. Assessment and treatment of anxiety disorders and co-morbid alcohol/other drug dependency. Alcohol Treat Q 2002; 20(1): 45–59.
• 16. Del Barrio V. Diagnostic and statistical manual of mental disorders. In: The Curated Reference Collection in Neuroscience and Biobehavioral Psychology 2016.
• 17. Beck AT, Kovacs M, Weissman A. Assessment of suicidal intention: The Scale for Suicide Ideation. J Consult Clin Psychol 1979; 47(2): 343–352.
• 18. Ozcelik HS, Ozdel K, Bulut SD, Orsel S. Measuring suicidal ideation: Validity and reliability of the turkish version of the beck scale for suicide ideation among patients who presented at a psychiatry clinic with suicidal ideations. Klin Psikofarmakol Bul 2015; 25(2): 142–50.
• 19. Goodman WK, Price LH, Rasmussen SA,et al. The Yale-Brown Obsessive Compulsive Scale: I. Development, Use, and Reliability. Arch Gen Psychiatry 1989; 46(11): 1006–1011.
• 20. Tek C, Uluǧ B, Rezaki BG,et al. Yale‐Brown Obsessive Compulsive Scale and US National Institute of Mental Health Global Obsessive Compulsive Scale in Turkish: reliability and validity. Acta Psychiatr Scand 1995; 91(6): 410–413.
• 21. Dell’Osso B, Benatti B, Arici C, et al. Prevalence of suicide attempt and clinical characteristics of suicide attempters with obsessive-compulsive disorder: A report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS). CNS Spectr 2018; 23(1): 59–66.
• 22. Karakuş G, Tamam L. Obsesif kompulsif bozuklukta uyku ve özkıyım ilişkisi. Anadolu Psikiyatr Derg 2018 ;19(1): 37–44.
• 23. Sher L. The impact of the COVID-19 pandemic on suicide rates. QJM: An International Journal of Medicine 2020; 113(10): 707–712.
• 24. Gunnell D, Appleby L, Arensman E, et al. Suicide risk and prevention during the COVID-19 pandemic.The Lancet Psychiatry 2020; 7(6): 468-471.
• 25. Yaryura-Tobias JA, Grunes MS, Todaro J, et al.Nosological insertion of Axis I disorders in the etiology of obsessive-compulsive disorder. J Anxiety Disord 2000 ;14(1): 19–30.
• 26. Gentil AF, Mathis MA de, Torresan RC, et al. Alcohol use disorders in patients with obsessive-compulsive disorder: The importance of appropriate dual-diagnosis. Drug Alcohol Depend 2009; 100(1–2): 173–177.
• 27. Karno M, Golding JM, Sorenson SB, Burnam MA. The Epidemiology of Obsessive-Compulsive Disorder in Five US Communities. Arch Gen Psychiatry 1988; 45(12): 1094–1099.
• 28. Torres AR, Prince MJ, Bebbington PE, et al. Obsessive-compulsive disorder: Prevalence, Comorbidity, impact, and help-seeking in the British National Psychiatric Morbidity Survey of 2000. Am J Psychiatry 2006;163(11):1978–1985.
• 29. Bystritsky A, Liberman RP, Hwang S, et al. Social functioning and quality of life comparisons between obsessive-compulsive and schizophrenic disorders. Depress Anxiety 2001;14(4):214–218.
• 30. World Health Organization. Global status report on alcohol and health. World Health Organization 2004.
• 31. Nock MK, Hwang I, Sampson NA, Kessler RC. Mental disorders, comorbidity and suicidal behavior: Results from the national comorbidity survey replication. Mol Psychiatry 2010; 15(8): 868–876.
• 32. Borges G, Walters EE, Kessler RC. Associations of substance use, abuse, and dependence with subsequent suicidal behavior. Am J Epidemiol 2000; 151(8): 781–789.
• 33. Petteri Sokero T, Melartin TK, Rytsälä HJ, et al.Suicidal ideation and attempts among psychiatric patients with major depressive disorder. J Clin Psychiatry 2003; 64(9): 1094–1100.
• 34. Brady J. The association between alcohol misuse and suicidal behaviour.Alcohol and Alcoholism 2006; 41(5): 473–478.
• 35. Gilpin NW, Koob GF. Neurobiology of alcohol dependence: Focus on motivational mechanisms.Alcohol Res Health 2008; 31(3): 185–195.