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Biological Activity and Chemical Composition of Jujuba (Ziziphus jujuba) Fruit

Year 2022, Volume: 11 Issue: Supplement 1 - Veterinary Pharmacology Congress Special Issue, 44 - 50, 01.12.2022
https://doi.org/10.53424/balikesirsbd.1159940

Abstract

Jujuba (Ziziphus jujuba) has a long history of usage as a fruit and remedy. The main biologically active components are vitamin C, phenolics, flavonoids, triterpenic acids, and polysaccharides. Many phytochemical studies of jujuba fruits indicate that Z. jujuba has important biological effects, such as the anticancer, anti-inflammatory, antiobesity, immunostimulant, antioxidant, hepatoprotective, neuroprotective and gastrointestinal protective activities. This review aims to explain bioactive characteristics of Z. jujuba by several examples of studies.

References

  • Chang SC, Hsu BY, Chen BH. Structural characterization of polysaccharides from Zizyphus jujuba and evaluation of antioxidant activity. Int J Biol Macromol, 2010, 47:445−453.
  • Chen J, Liu X, Li Z, Qi A, Yao P, Zhou Z, Dong TTX, Tsim KWK. A review of dietary Ziziphus jujuba fruit (Jujube): Developing health food supplements for brain protection. Evid Based Complement Alternat Med, 2017, 3019568:1-10.
  • Chen J, Maiwulanjiang M, Lam KYC, Zhang WL, Zhan JYX, Lam CTW, Xu SL,Zhu KY, Yao P, Lau DTW, Dong TTX, TSim KWK. A standardized extract of the fruit of Ziziphus jujuba (Jujube) induces neuronal differentiation of cultured PC12 cells: A signaling mediated by protein kinase A. J Agric Food Chem, 2014, 62:1890−1897.
  • Cui G, Zhang w, Wang Q, Zhang A, Mu H, Bai H, Duan J. Extraction optimization, characterization and immunity activity of polysaccharides from Fructus Jujubae. Carbohydr Polym, 2014, 111:245–255.
  • Guo S, Duan JA, Tang Y, Su S, Shang E, Ni S, Qian D. High-performance liquid chromatography–two wavelength detection of triterpenoid acids from the fruits of Ziziphus jujuba containing various cultivars in different regions and classification using chemometric analysis. J Pharm Biomed Anal, 2009, 49:1296–1302.
  • Guo S, Duan JA, Tang, YP, Yang NY, Qian DW, Su SL, Shang EX. Characterization of triterpenic acids in fruits of Ziziphus species by HPLC-ELSD-MS. J Agric Food Chem, 2010, 58:6285–6289.
  • Ji X, Peng Q, Yuan Y, Shen J, Xie X, Wang M. Isolation, structures and bioactivities of the polysaccharides from jujube fruit (Ziziphus jujuba Mill.): A review. Food Chem, 2017, 227:349–357.
  • Ji X, Liu F, Ullah N, Wang M. Isolation, purification, and antioxidant activities of polysaccharides from Ziziphus Jujuba cv. Muzao. Int J Food Prop, 2018, 21:1-11.
  • Kawabata K, Kitamura K, Irie K, Naruse S, Matsuura T, Uemae T, Taira S, Ohigashi H, Murakami S, Takahashi M, Kaido Y, Kawakami B. Triterpenoids isolated from Ziziphus jujuba enhance glucose uptake activity in skeletal muscle cells. J Nutr Sci Vitaminol, 2017, 63:193-199.
  • Li JW, Fan LP, Ding SD, Ding XL. Nutritional composition of five cultivars of chinese jujube. Food Chem, 2007, 103:454–460.
  • Mahajan RT, Chopda MZ. Phyto-pharmacology of Ziziphus jujuba Mill. - A plant review. Pharmacogn Rev, 2009, 3(6):320-329.
  • San B, Yildirim AN. Phenolic, α-tocopherol, β-carotene and fatty acid composition of four promising jujube (Ziziphus jujuba Miller) selections. J Food Comp Anal, 2010, 23:706–710.
  • Sun YF, Liang ZS, Shan CJ, Viernstein H, Unger F. Comprehensive evaluation of natural antioxidants and antioxidant potentials in Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex H. F. Chou fruits based on geographical origin by TOPSIS method. Food Chem, 2011, 124:1612−1619.
  • Wang BN, Liu HF, Zheng JB, Fan MT, Cao W. Distribution of phenolic acids in different tissues of jujube and their antioxidant activity. J Agric Food Chem, 2011, 59:1288−1292.
  • Wang, M., Gao, Q. H., Shen, J., Wang, X. Q., & Ji, X. L. (2016). The jujube (Ziziphus jujuba Mill.) fruit: a review of current knowledge of fruit composition and health benefits. Chinese Dates, 53-82.
  • Wang Y, Liu X, Zhang J, Liu G, Liu Y, Wang K, Yang M, Cheng H. Structural characterization and in vitro antitumor activity of polysaccharides from Zizyphus jujuba cv. Muzao. RSV Adv, 2015, 5:7860-7867.

Hünnap (Ziziphus jujuba) Meyvesinin Biyolojik Etkinliği ve Kimyasal Bileşimi

Year 2022, Volume: 11 Issue: Supplement 1 - Veterinary Pharmacology Congress Special Issue, 44 - 50, 01.12.2022
https://doi.org/10.53424/balikesirsbd.1159940

Abstract

Hünnap (Ziziphus jujuba), meyve ve ilaç olarak uzun bir kullanım geçmişine sahiptir. Biyolojik olarak etkin olan ana bileşenleri C vitamini, fenolik bileşikler, flavonoidler, triterpenik asitler ve polisakkaritlerdir. Hünnap meyvelerinin birçok fitokimyasal incelenmesi sonucunda; antikanser, anti-inflammatuvar, anti-obezite, immunstimülan, antioksidan, başta karaciğer olmak üzere, gastrointestinal ve sinir sistemlerini korumak gibi önemli biyolojik etkilere sahip oldukları gösterilmiştir. Bu derleme, hünnapın biyo-etkin özelliklerini örnek çalışmalarla açıklamayı amaçlamıştır.

References

  • Chang SC, Hsu BY, Chen BH. Structural characterization of polysaccharides from Zizyphus jujuba and evaluation of antioxidant activity. Int J Biol Macromol, 2010, 47:445−453.
  • Chen J, Liu X, Li Z, Qi A, Yao P, Zhou Z, Dong TTX, Tsim KWK. A review of dietary Ziziphus jujuba fruit (Jujube): Developing health food supplements for brain protection. Evid Based Complement Alternat Med, 2017, 3019568:1-10.
  • Chen J, Maiwulanjiang M, Lam KYC, Zhang WL, Zhan JYX, Lam CTW, Xu SL,Zhu KY, Yao P, Lau DTW, Dong TTX, TSim KWK. A standardized extract of the fruit of Ziziphus jujuba (Jujube) induces neuronal differentiation of cultured PC12 cells: A signaling mediated by protein kinase A. J Agric Food Chem, 2014, 62:1890−1897.
  • Cui G, Zhang w, Wang Q, Zhang A, Mu H, Bai H, Duan J. Extraction optimization, characterization and immunity activity of polysaccharides from Fructus Jujubae. Carbohydr Polym, 2014, 111:245–255.
  • Guo S, Duan JA, Tang Y, Su S, Shang E, Ni S, Qian D. High-performance liquid chromatography–two wavelength detection of triterpenoid acids from the fruits of Ziziphus jujuba containing various cultivars in different regions and classification using chemometric analysis. J Pharm Biomed Anal, 2009, 49:1296–1302.
  • Guo S, Duan JA, Tang, YP, Yang NY, Qian DW, Su SL, Shang EX. Characterization of triterpenic acids in fruits of Ziziphus species by HPLC-ELSD-MS. J Agric Food Chem, 2010, 58:6285–6289.
  • Ji X, Peng Q, Yuan Y, Shen J, Xie X, Wang M. Isolation, structures and bioactivities of the polysaccharides from jujube fruit (Ziziphus jujuba Mill.): A review. Food Chem, 2017, 227:349–357.
  • Ji X, Liu F, Ullah N, Wang M. Isolation, purification, and antioxidant activities of polysaccharides from Ziziphus Jujuba cv. Muzao. Int J Food Prop, 2018, 21:1-11.
  • Kawabata K, Kitamura K, Irie K, Naruse S, Matsuura T, Uemae T, Taira S, Ohigashi H, Murakami S, Takahashi M, Kaido Y, Kawakami B. Triterpenoids isolated from Ziziphus jujuba enhance glucose uptake activity in skeletal muscle cells. J Nutr Sci Vitaminol, 2017, 63:193-199.
  • Li JW, Fan LP, Ding SD, Ding XL. Nutritional composition of five cultivars of chinese jujube. Food Chem, 2007, 103:454–460.
  • Mahajan RT, Chopda MZ. Phyto-pharmacology of Ziziphus jujuba Mill. - A plant review. Pharmacogn Rev, 2009, 3(6):320-329.
  • San B, Yildirim AN. Phenolic, α-tocopherol, β-carotene and fatty acid composition of four promising jujube (Ziziphus jujuba Miller) selections. J Food Comp Anal, 2010, 23:706–710.
  • Sun YF, Liang ZS, Shan CJ, Viernstein H, Unger F. Comprehensive evaluation of natural antioxidants and antioxidant potentials in Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex H. F. Chou fruits based on geographical origin by TOPSIS method. Food Chem, 2011, 124:1612−1619.
  • Wang BN, Liu HF, Zheng JB, Fan MT, Cao W. Distribution of phenolic acids in different tissues of jujube and their antioxidant activity. J Agric Food Chem, 2011, 59:1288−1292.
  • Wang, M., Gao, Q. H., Shen, J., Wang, X. Q., & Ji, X. L. (2016). The jujube (Ziziphus jujuba Mill.) fruit: a review of current knowledge of fruit composition and health benefits. Chinese Dates, 53-82.
  • Wang Y, Liu X, Zhang J, Liu G, Liu Y, Wang K, Yang M, Cheng H. Structural characterization and in vitro antitumor activity of polysaccharides from Zizyphus jujuba cv. Muzao. RSV Adv, 2015, 5:7860-7867.
There are 16 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Derlemeler
Authors

Serkan Korkut 0000-0003-0849-0617

Şahver Ege Hişmioğulları 0000-0002-0868-502X

Adnan Adil Hismioğulları 0000-0001-7459-6319

Publication Date December 1, 2022
Submission Date August 9, 2022
Published in Issue Year 2022 Volume: 11 Issue: Supplement 1 - Veterinary Pharmacology Congress Special Issue

Cite

APA Korkut, S., Hişmioğulları, Ş. E., & Hismioğulları, A. A. (2022). Hünnap (Ziziphus jujuba) Meyvesinin Biyolojik Etkinliği ve Kimyasal Bileşimi. Balıkesir Sağlık Bilimleri Dergisi, 11(Supplement 1), 44-50. https://doi.org/10.53424/balikesirsbd.1159940

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