The Relationship of Fractal Dimension and Osseointegration: A Retrospective Radiologic Clinical Trial
Year 2024,
Volume: 13 Issue: 3, 737 - 744, 25.12.2024
Fatma Akkoca
,
Turan Emre Kuzu
,
Günnur İlhan
Abstract
Objective: The objective of this study was to evaluate the density of alveolar bone in the peri-implant area using fractal analysis on orthopantomograms, both prior to and following clinical osseointegration. Material and Methods: Orthopantomograms were performed prior to the implant surgery and again four months postoperatively. Regions of interest at the mesial, distal, and apical sites of the implants were identified for analysis. The method by White and Rudolph was employed to calculate the fractal dimension. Subsequently, fractal dimension values were compared across all recorded measurements. Results: Statistical analyses revealed significant correlations between the mesial measurements before and after surgery, as well as between the distal measurements pre- and post-operatively, compared to the apical measurements over the same periods. Further subgroup analyses identified significant correlations in pre- and post-operative fractal dimension values specifically within the female subgroup, with notable distinctions observed between pre-mesial, post-mesial, and the average values before and after surgery (p<0.05). Moreover, substantial differences were detected between the jaws (p<0.05) and the specific locations within the jaws (p>0.05), regarding the fractal dimensions measured pre- and post-operatively. Conclusion: Fractal analysis has demonstrated its reliability as a method for both clinical and radiological assessment of osseointegration.
Ethical Statement
The Relationship of Fractal Dimension and Osseointegration: A Retrospective Radiologic Clinical Trial adli calismanin yürütülmesinde bilimsel ve etik kurallara uyduğumu, araştırmanın Etik kurul izni gerektiren çalışmalar kapsamına giren bir çalışma olmadığını, etik kurul izni gerektirmediğini ve bu durumu calışmanın yönteminde belirttiğimi beyanederim.
Supporting Institution
YOK
References
- August, M., Chung, K., Chang, Y., & Glowacki, J. (2001). Influence of estrogen status on endosseous implant osseointegration. Journal of oral and maxillofacial surgery, 59(11), 1285-1289.
- Arsan B., Kose T., Cene E., & Ozcan I. (2017) Assessment of the trabecular structure of mandibular condyles in patients with temporomandibular disorders using fractal analysis. Oral Surgery, Oral Medicine, Oral Pathology Oral Radiology, 123(3):382-391.
- Balshi, S. F., Allen, F. D., Wolfinger, G. J., & Balshi, T. J. (2005). A resonance frequency analysis assessment of maxillary and mandibular immediately loaded implants. International Journal of Oral & Maxillofacial Implants, 20(4). https://doi.org/10.11607/jomi.3910
- Bornstein, M. M., Hart, C. N., Halbritter, S. A., Morton, D., & Buser, D. (2009). Early loading of nonsubmerged titanium implants with a chemically modified sand‐blasted and acid‐etched surface: 6‐month results of a prospective case series study in the posterior mandible focusing on peri‐implant crestal bone changes and implant stability quotient (ISQ) values. Clinical Implant Dentistry and Related Research, 11(4), 338-347.
- Cakur, B., Şahin, A., Dagistan, S., Altun, O., Caglayan, F., Miloglu, Ö., & Harorli, A. (2008). Dental panoramic radiography in the diagnosis of osteoporosis. Journal of International Medical Research, 36(4), 792-799. https://doi.org/10.1177/147323000803600422
- Castellanos-Cosano, L., Rodriguez-Perez, A., Spinato, S., Wainwright, M., Machuca-Portillo, G., Serrera-Figallo, M. A., & Torres-Lagares, D. (2019). Descriptive retrospective study analyzing relevant factors related to dental implant failure. Medicina Oral, Patologia Oral, Ciruli Bucal 24(6), e726
- Cesur, E., Bayrak, S., Kursun-Çakmak, E. Ş., Arslan, C., Köklü, A., & Orhan, K. (2020). Evaluating the effects of functional orthodontic treatment on mandibular osseous structure using fractal dimension analysis of dental panoramic radiographs. The Angle Orthodontist, 90(6), 783-793. https://doi.org/10.2319/012020-39.1
- Chen, M. H. M., Lyons, K., Tawse-Smith, A., & Ma, S. (2019). Resonance frequency analysis in assessing implant stability: a retrospective analysis. The International Journal of Prosthodontics, 32(4), 317-326.
- Geraets, W. G., & Van Der Stelt, P. F. (2000). Fractal properties of bone. Dentomaxillofacial Radiology, 29(3),144-153. https://doi.org/10.1038/sj/dmfr/4600524 29(3)
- Gupta R., Gupta N., Kurt K., & Weber D., Bioceramics Calcium Phosphate. Dental Implants, 2023;115–30.
Heo, M. S., Park, K. S., Lee, S. S., Choi, S. C., Koak, J. Y., Heo, S. J., & Kim, J. D. (2002). Fractal analysis of mandibular bony healing after orthognathic surgery. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 94(6), 763-767.
https://doi.org/10.1067/moe.2002.128972
- Ibrahim, N., Parsa, A., Hassan, B., van der Stelt, P., Aartman, I. H., & Wismeijer, D. (2014). Accuracy of trabecular bone microstructural measurement at planned dental implant sites using cone‐beam CT datasets. Clinical Oral Implants Research, 25(8), 941-945.
- Jeong, K. I., Kim, S. G., Oh, J. S., & Jeong, M. A. (2013). Consideration of various bone quality evaluation methods. Implant Dentistry, 22(1), 55-59.
https://doi.org/10.1097/id.0b013e31827778d9
- Koh, K. J., Park, H. N., & Kim, K. A. (2012). Prediction of age-related osteoporosis using fractal analysis on panoramic radiographs. Imaging science in dentistry, 42(4), 231.
- Lee, D. H., Ku, Y., Rhyu, I. C., Hong, J. U., Lee, C. W., Heo, M. S., & Huh, K. H. (2010). A clinical study of alveolar bone quality using the fractal dimension and the implant stability quotient. Journal of Periodontal & Implant Science, 40(1), 19.
https://doi.org/10.5051/jpis.2010.40.1.19
- Oliveira, M. L., Pedrosa, E. F. N. C., Cruz, A. D., Haiter-Neto, F., Paula, F. J. A., & Watanabe, P. C. A. (2013). Relationship between bone mineral density and trabecular bone pattern in postmenopausal osteoporotic Brazilian women. Clinical Oral Investigations, 17, 1847-1853.
https://doi.org/10.1007/s00784-012-0882-2
- Mandelbrot, B. B., & Mandelbrot, B. B. (1982). The Fractal Geometry of Nature (Vol. 1, pp. 25-74). New York: WH freeman.
- Mangano, F. G., Oskouei, S. G., Paz, A., Mangano, N., & Mangano, C. (2018). Low serum vitamin D and early dental implant failure: Is there a connection? A retrospective clinical study on 1740 implants placed in 885 patients. Journal of Dental Research, Dental Clinics, Dental Prospects, 12(3), 174.
https://doi.org/10.15171/joddd.2018.027
- Milillo, L., Fiandaca, C., Giannoulis, F., Ottria, L., Lucchese, A., Silvestre, F., & Petruzzi, M. (2016). Immediate vs non-immediate loading post-extractive implants: A comparative study of Implant Stability Quotient (ISQ). Oral & Implantology, 9(3), 123.
- Mu, T. J., Lee, D. W., Park, K. H., & Moon, I. S. (2013). Changes in the fractal dimension of peri-implant trabecular bone after loading: a retrospective study. Journal of Periodontal & Implant Science, 43(5), 209
.
Obamiyi, S., Malik, S., Wang, Z., Singh, S., Rossouw, E. P., Fishman, L., & Tallents, R. H. (2018). Radiographic features associated with temporomandibular joint disorders among African, White, Chinese, Hispanic, and Indian racial groups. Nigerian Journal of Clinical Practice, 21(11), 1495-1500.
- Wilding, R. J. C., Slabbert, J. C. G., Kathree, H., Owen, C. P., Crombie, K., & Delport, P. (1995). The use of fractal analysis to reveal remodelling in human alveolar bone following the placement of dental implants. Archives of Oral Biology, 40(1), 61-72.
https://doi.org/10.1016/0003-9969(94)00138-2
- Parkinson H. Fazzalari N L, and. 1996. “Fractal Dimension and Architecture of Trabecular Bone.” The Journal of pathology 178(1): 100–105.
- Ruggiero, S. L., Mehrotra, B., Rosenberg, T. J., & Engroff, S. L. (2004). Osteonecrosis of the jaws associated with the use of bisphosphonates: a review of 63 cases. Journal of Oral and Maxillofacial Surgery, 62(5), 527-534.
- Sánchez, I., & Uzcátegui, G. (2011). Fractals in dentistry. Journal of Dentistry, 39(4), 273-292.
- Sansare, K., Singh, D., & Karjodkar, F. (2012). Changes in the fractal dimension on pre-and post-implant panoramic radiographs. Oral Radiology, 28, 15-23.
- Soğur, E., & Baksı, B. G. (2014). Imaging systems used for diagnosis of periodontal pathology Part 2: Alternative Imaging Systems and Image Processing Methods. Journal of Ege University School of Dentistry 35(1), 10-18. https://doi.org/10.5505/eudfd.2014.47364
- Soylu, E., Coşgunarslan, A., Çelebi, S., Soydan, D., Demirbaş, A. E., & Demir, O. (2021). Fractal analysis as a useful predictor for determining osseointegration of dental implant? A retrospective study. International Journal of Implant Dentistry, 7, 1-8.
- Tözüm, T. F., Bal, B. T., Turkyilmaz, I., Gülay, G., & Tulunoglu, I. (2010). Which device is more accurate to determine the stability/mobility of dental implants? A human cadaver study. Journal of Oral Rehabilitation, 37(3), 217-224.
https://doi.org/10.1111/j.1365-2842.2009.02038.x
- Zeytinoğlu, M., İlhan, B., Dündar, N., & Boyacioğlu, H. (2015). Fractal analysis for the assessment of trabecular peri-implant alveolar bone using panoramic radiographs. Clinical Oral Investigations, 19, 519-524.
https://doi.org/10.1007/s00784-014-1245-y
Fraktal Boyut ve Ossentegrasyon İlişkisi: Retrospektif Radyolojik Klinik Deneme
Year 2024,
Volume: 13 Issue: 3, 737 - 744, 25.12.2024
Fatma Akkoca
,
Turan Emre Kuzu
,
Günnur İlhan
Abstract
Amaç: Bu çalışmanın amacı, klinik ossentegrasyon öncesi ve sonrasında ortopantomogramlar üzerinde fraktal analiz kullanarak alveolar kemik yoğunluğunu değerlendirmektir. Gereç ve Yöntem: İmplant cerrahisi öncesinde ve ameliyattan dört ay sonra ortopantomogramlar çekildi. İmplantların mezial, distal ve apikal bölgelerinde analiz için ilgi alanları belirlendi. Fraktal boyut hesaplamak için White ve Rudolph yöntemi kullanıldı. Daha sonra, kaydedilen tüm ölçümlerde fraktal boyut değerleri karşılaştırıldı. Bulgular: İstatistiksel analizler, cerrahi öncesi ve sonrası mezial ölçümler arasında, aynı dönemlerde apikal ölçümlere kıyasla distal ölçümler arasında önemli korelasyonlar ortaya koydu. Daha fazla alt grup analizleri, özellikle kadın alt grubu içinde cerrahi öncesi ve sonrası fraktal boyut değerlerinde önemli korelasyonlar saptadı; cerrahi öncesi-mezial, cerrahi sonrası-mezial ve cerrahi öncesi ve sonrası ortalama değerler arasında belirgin farklar gözlemlendi (p<0.05). Ayrıca, çeneler arasında (p<0.05) ve çeneler içindeki spesifik lokasyonlar arasında (p>0.05), cerrahi öncesi ve sonrası ölçülen fraktal boyutlar açısından önemli farklar tespit edildi. Sonuç: Fraktal analiz, klinik ve radyolojik ossentegrasyon değerlendirmesi için güvenilir bir yöntem olarak kendini kanıtlamıştır.
References
- August, M., Chung, K., Chang, Y., & Glowacki, J. (2001). Influence of estrogen status on endosseous implant osseointegration. Journal of oral and maxillofacial surgery, 59(11), 1285-1289.
- Arsan B., Kose T., Cene E., & Ozcan I. (2017) Assessment of the trabecular structure of mandibular condyles in patients with temporomandibular disorders using fractal analysis. Oral Surgery, Oral Medicine, Oral Pathology Oral Radiology, 123(3):382-391.
- Balshi, S. F., Allen, F. D., Wolfinger, G. J., & Balshi, T. J. (2005). A resonance frequency analysis assessment of maxillary and mandibular immediately loaded implants. International Journal of Oral & Maxillofacial Implants, 20(4). https://doi.org/10.11607/jomi.3910
- Bornstein, M. M., Hart, C. N., Halbritter, S. A., Morton, D., & Buser, D. (2009). Early loading of nonsubmerged titanium implants with a chemically modified sand‐blasted and acid‐etched surface: 6‐month results of a prospective case series study in the posterior mandible focusing on peri‐implant crestal bone changes and implant stability quotient (ISQ) values. Clinical Implant Dentistry and Related Research, 11(4), 338-347.
- Cakur, B., Şahin, A., Dagistan, S., Altun, O., Caglayan, F., Miloglu, Ö., & Harorli, A. (2008). Dental panoramic radiography in the diagnosis of osteoporosis. Journal of International Medical Research, 36(4), 792-799. https://doi.org/10.1177/147323000803600422
- Castellanos-Cosano, L., Rodriguez-Perez, A., Spinato, S., Wainwright, M., Machuca-Portillo, G., Serrera-Figallo, M. A., & Torres-Lagares, D. (2019). Descriptive retrospective study analyzing relevant factors related to dental implant failure. Medicina Oral, Patologia Oral, Ciruli Bucal 24(6), e726
- Cesur, E., Bayrak, S., Kursun-Çakmak, E. Ş., Arslan, C., Köklü, A., & Orhan, K. (2020). Evaluating the effects of functional orthodontic treatment on mandibular osseous structure using fractal dimension analysis of dental panoramic radiographs. The Angle Orthodontist, 90(6), 783-793. https://doi.org/10.2319/012020-39.1
- Chen, M. H. M., Lyons, K., Tawse-Smith, A., & Ma, S. (2019). Resonance frequency analysis in assessing implant stability: a retrospective analysis. The International Journal of Prosthodontics, 32(4), 317-326.
- Geraets, W. G., & Van Der Stelt, P. F. (2000). Fractal properties of bone. Dentomaxillofacial Radiology, 29(3),144-153. https://doi.org/10.1038/sj/dmfr/4600524 29(3)
- Gupta R., Gupta N., Kurt K., & Weber D., Bioceramics Calcium Phosphate. Dental Implants, 2023;115–30.
Heo, M. S., Park, K. S., Lee, S. S., Choi, S. C., Koak, J. Y., Heo, S. J., & Kim, J. D. (2002). Fractal analysis of mandibular bony healing after orthognathic surgery. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 94(6), 763-767.
https://doi.org/10.1067/moe.2002.128972
- Ibrahim, N., Parsa, A., Hassan, B., van der Stelt, P., Aartman, I. H., & Wismeijer, D. (2014). Accuracy of trabecular bone microstructural measurement at planned dental implant sites using cone‐beam CT datasets. Clinical Oral Implants Research, 25(8), 941-945.
- Jeong, K. I., Kim, S. G., Oh, J. S., & Jeong, M. A. (2013). Consideration of various bone quality evaluation methods. Implant Dentistry, 22(1), 55-59.
https://doi.org/10.1097/id.0b013e31827778d9
- Koh, K. J., Park, H. N., & Kim, K. A. (2012). Prediction of age-related osteoporosis using fractal analysis on panoramic radiographs. Imaging science in dentistry, 42(4), 231.
- Lee, D. H., Ku, Y., Rhyu, I. C., Hong, J. U., Lee, C. W., Heo, M. S., & Huh, K. H. (2010). A clinical study of alveolar bone quality using the fractal dimension and the implant stability quotient. Journal of Periodontal & Implant Science, 40(1), 19.
https://doi.org/10.5051/jpis.2010.40.1.19
- Oliveira, M. L., Pedrosa, E. F. N. C., Cruz, A. D., Haiter-Neto, F., Paula, F. J. A., & Watanabe, P. C. A. (2013). Relationship between bone mineral density and trabecular bone pattern in postmenopausal osteoporotic Brazilian women. Clinical Oral Investigations, 17, 1847-1853.
https://doi.org/10.1007/s00784-012-0882-2
- Mandelbrot, B. B., & Mandelbrot, B. B. (1982). The Fractal Geometry of Nature (Vol. 1, pp. 25-74). New York: WH freeman.
- Mangano, F. G., Oskouei, S. G., Paz, A., Mangano, N., & Mangano, C. (2018). Low serum vitamin D and early dental implant failure: Is there a connection? A retrospective clinical study on 1740 implants placed in 885 patients. Journal of Dental Research, Dental Clinics, Dental Prospects, 12(3), 174.
https://doi.org/10.15171/joddd.2018.027
- Milillo, L., Fiandaca, C., Giannoulis, F., Ottria, L., Lucchese, A., Silvestre, F., & Petruzzi, M. (2016). Immediate vs non-immediate loading post-extractive implants: A comparative study of Implant Stability Quotient (ISQ). Oral & Implantology, 9(3), 123.
- Mu, T. J., Lee, D. W., Park, K. H., & Moon, I. S. (2013). Changes in the fractal dimension of peri-implant trabecular bone after loading: a retrospective study. Journal of Periodontal & Implant Science, 43(5), 209
.
Obamiyi, S., Malik, S., Wang, Z., Singh, S., Rossouw, E. P., Fishman, L., & Tallents, R. H. (2018). Radiographic features associated with temporomandibular joint disorders among African, White, Chinese, Hispanic, and Indian racial groups. Nigerian Journal of Clinical Practice, 21(11), 1495-1500.
- Wilding, R. J. C., Slabbert, J. C. G., Kathree, H., Owen, C. P., Crombie, K., & Delport, P. (1995). The use of fractal analysis to reveal remodelling in human alveolar bone following the placement of dental implants. Archives of Oral Biology, 40(1), 61-72.
https://doi.org/10.1016/0003-9969(94)00138-2
- Parkinson H. Fazzalari N L, and. 1996. “Fractal Dimension and Architecture of Trabecular Bone.” The Journal of pathology 178(1): 100–105.
- Ruggiero, S. L., Mehrotra, B., Rosenberg, T. J., & Engroff, S. L. (2004). Osteonecrosis of the jaws associated with the use of bisphosphonates: a review of 63 cases. Journal of Oral and Maxillofacial Surgery, 62(5), 527-534.
- Sánchez, I., & Uzcátegui, G. (2011). Fractals in dentistry. Journal of Dentistry, 39(4), 273-292.
- Sansare, K., Singh, D., & Karjodkar, F. (2012). Changes in the fractal dimension on pre-and post-implant panoramic radiographs. Oral Radiology, 28, 15-23.
- Soğur, E., & Baksı, B. G. (2014). Imaging systems used for diagnosis of periodontal pathology Part 2: Alternative Imaging Systems and Image Processing Methods. Journal of Ege University School of Dentistry 35(1), 10-18. https://doi.org/10.5505/eudfd.2014.47364
- Soylu, E., Coşgunarslan, A., Çelebi, S., Soydan, D., Demirbaş, A. E., & Demir, O. (2021). Fractal analysis as a useful predictor for determining osseointegration of dental implant? A retrospective study. International Journal of Implant Dentistry, 7, 1-8.
- Tözüm, T. F., Bal, B. T., Turkyilmaz, I., Gülay, G., & Tulunoglu, I. (2010). Which device is more accurate to determine the stability/mobility of dental implants? A human cadaver study. Journal of Oral Rehabilitation, 37(3), 217-224.
https://doi.org/10.1111/j.1365-2842.2009.02038.x
- Zeytinoğlu, M., İlhan, B., Dündar, N., & Boyacioğlu, H. (2015). Fractal analysis for the assessment of trabecular peri-implant alveolar bone using panoramic radiographs. Clinical Oral Investigations, 19, 519-524.
https://doi.org/10.1007/s00784-014-1245-y