Some Important Medicinal Mushrooms in Asian Traditional Medicine Detected on Liquidambar orientalis Mill.

Year 2024, Volume: 5 Issue: 3, 85 - 97, 31.12.2024

Selime Semra Erol , Hakan Allı

https://doi.org/10.53445/batd.1552964

Abstract

Purpose: Mycotherapy can be defined as the use of medicinal fungi as an adjuvant treatment method within the scope of Traditional and Complementary Medicine (GETAT) practices. A comprehensive understanding of mycotherapy applications is of great importance for its integration with modern medicine. The aim of this study was to identify the medicinal mushroom species growing on Liquidambar orientalis Mill. used in mycotherapy applications and to investigate their use in folk medicine.

Materials and methods: The material of the study consisted of 6 medicinal mushroom species identified on Liquidambar orientalis growing in Muğla province. The identification of the identified species was carried out according to the existing literature using appropriate mycological techniques.

Results: The medicinal mushroom species identified were Ganoderma lucidum (Curtis) P. Karst., Trametes versicolor (L.) Lloyd, Auricularia auricula-judae (Bull.) Quél, Fomes fomentarius (L.) Fr., Schizophyllum commune Fr., Lentinus tigrinus (Bull.) Fr.

Conclusion: The medicinal mushrooms described are important species in Asian traditional medicine. Although these medicinal mushrooms have been used in Asian traditional medicine since ancient times, they are not well known in Türkiye. In this study, 6 medicinal mushroom species identified in Türkiye, which are frequently used in Asian Traditional Medicine, were identified; the common uses of these species in Asian Traditional Medicine and the knowledge of local people about the identified species were given.

Keywords

Traditional and complementary medicine, folk medicine, mycotherapy, medicinal mushrooms

Liquidambar orientalis Mill. Üzerinde Tespit Edilen Asya Geleneksel Tıbbında Önemli Bazı Tıbbi Mantarlar

Abstract

Amaç: Mikoterapi, Geleneksel ve Tamamlayıcı Tıp (GETAT) uygulamaları kapsamında tıbbi mantarların adjuvan tedavi yöntemi olarak kullanılması şeklinde tanımlanabilir. Mikoterapi uygulamalarının kapsamlı bir şekilde anlaşılması, modern tıp ile entegrasyonu açısından büyük önem taşımaktadır. Bu çalışmanın amacı, mikoterapi uygulamalarında kullanılan, Liquidambar orientalis Mill. üzerinde yetişen tıbbi mantar türlerini tanımlamak ve halk hekimliğinde kullanımlarını araştırmaktır.

Materyal ve metot: Çalışmanın materyalini Muğla ili sınırları içerisinde yetişen Liquidambar orientalis üzerinde belirlenen 6 tıbbi mantar türü oluşturmaktadır. Tespit edilen türlerin tanımlamaları uygun mikolojik teknikler kullanılarak mevcut literatüre göre yapılmıştır.

Bulgular: Tanımlanan tıbbi mantar türleri; Ganoderma lucidum (Curtis) P. Karst., Trametes versicolor (L.) Lloyd, Auricularia auricula-judae (Bull.) Quél, Fomes fomentarius (L.) Fr., Schizophyllum commune Fr., Lentinus tigrinus (Bull.) Fr.’dir.

Sonuç: Tanımlanan tıbbi mantarlar Asya geleneksel tıbbında önemli türlerdir. Bu tıbbi mantarlar, Asya geleneksel tıbbında eski çağlardan beri kullanılmasına rağmen, Türkiye’de iyi bilinmemektedir. İlgili çalışmada, ülkemizde tespit edilen ve özellikle Asya Geleneksel Tıbbında sıklıkla kullanılan 6 tıbbi mantar türü tanımlanmış; bu türlerin Asya Geleneksel Tıbbında yaygın kullanım alanları ve yöre halkının tespit edilen türlere ilişkin bilgi birikimi verilmiştir.

Keywords

Geleneksel ve tamamlayıcı tıp, halk hekimliği, mikoterapi, tıbbi mantarlar

References

• Akalın, K. H. (2016). Mitlerin Yaşamamış İnsan-Tanrılarından İncillerdeki Tek Tanrı-İnsanı Sembolik İsa’ya Geçiş. Iğdır Üniversitesi İlahiyat Fakültesi Dergisi, (7), 171-223.
• Aung, S. K. (2005). The clinical use of mushrooms from a Traditional Chinese Medical perspective. International Journal of Medicinal Mushrooms, 7(3).
• Bao, X., Liu, C., Fang, J., and Li, X. (2001). Structural and immunological studies of a major polysaccharide from spores of Ganoderma lucidum (Fr.) Karst. Carbohydrate research, 332(1), 67-74.
• Breitenbach, J. ve Kränzlin, F. (1984). Fungi of Switzerland. Vol.1, Verlag Mykologia Lucerne, Switzerland.
• Breitenbach, J. ve Kränzlin, F. (1986). Fungi of Switzerland. Vol.2, Verlag Mykologia Lucerne, Switzerland.
• Breitenbach, J. ve Kränzlin, F. (1991). Fungi of Switzerland. Vol.3, Verlag Mykologia Lucerne, Switzerland.
• Breitenbach, J. ve Kränzlin, F. (1995). Fungi of Switzerland. Vol.4, Verlag Mykologia Lucerne, Switzerland.
• Breitenbach, J. ve Kränzlin, F. (2000). Fungi of Switzerland. Vol.5, Verlag Mykologia Lucerne, Switzerland.
• Cao, L. Z., and Lin, Z. B. (2002). Regulation on maturation and function of dendritic cells by Ganoderma lucidum polysaccharides. Immunology letters, 83(3), 163-169.
• Chen, W., Zhao, Z., and Li, Y. (2011). Simultaneous increase of mycelial biomass and intracellular polysaccharide from Fomes fomentarius and its biological function of gastric cancer intervention. Carbohydrate Polymers, 85(2), 369-375.
• Dai, Y. C., Yang, Z. L., Cui, B. K., Yu, C. J., and Zhou, L. W. (2009). Species diversity and utilization of medicinal mushrooms and fungi in China. International journal of medicinal mushrooms, 11(3).
• Dulay, R. M. R., Miranda, L. A., Malasaga, J. S., Kalaw, S. P., Reyes, R. G., and Hou, C. T. (2017). Antioxidant and antibacterial activities of acetonitrile and hexane extracts of Lentinus tigrinus and Pleurotus djamour. Biocatalysis and Agricultural Biotechnology, 9, 141-144.
• Elkhateeb, W., Elnahas, M. O., Paul, W., and Daba, G. M. (2020). Fomes fomentarius and Polyporus squamosus models of marvel medicinal mushrooms. Biomed. Res. Rev, 3(1), 1-4.
• Erol, S. S., ve Allı, H. (2024). Armutlu (Yalova) Yöresinin Ekonomik Değere Sahip Makromantarları. Mantar Dergisi, 15(2), 87-93.
• Erol, S. S., Akata, I., and Kaya, E. (2020). Use of Macrofungi in Traditional and Complementary Medicine Practices: Mycotherapy. International Journal of Traditional and Complementary Medicine Research, 1(2), 70-78.
• Gafforov, Y., İnci, Ş., Rašeta, M., Cazabonne, J., Erol S, S., Yarasheva, M., and Rapior, S. (2023). Morchella esculenta (L.) Pers.; Morchella steppicola Zerova-MORCHELLACEAE. In Ethnobiology of Uzbekistan: Ethnomedicinal Knowledge of Mountain Communitie (pp. 1285-1308). Cham: Springer International Publishing.
• Gafforov, Y., Rašeta, M., Rapior, S., Yarasheva, M., Wang, X., Zhou, L., and Chen, J. (2023). Macrofungi as medicinal resources in Uzbekistan: biodiversity, ethnomycology, and ethnomedicinal practices. Journal of Fungi, 9(9), 922.
• Geleneksel ve Tamamlayıcı Tıp Uygulamaları Yönetmeliği. (2014). T.C. Resmî Gazete, 29158.
• Geneva, W. H. O. (2000). World health organization general guidelines for methodologies on research and evaluation of traditional medicine. WHO: Geneva, 82.
• He, Y., Liu, S., and Newburg, D. S. (2021). Musarin, a novel protein with tyrosine kinase inhibitory activity from Trametes versicolor, inhibits colorectal cancer stem cell growth. Biomedicine and Pharmacotherapy, 144, 112339.
• Hobbs, C. (2005). The chemistry, nutritional value, immunopharmacology, and safety of the traditional food of medicinal split-gill fugus Schizophyllum commune Fr.: Fr. (Schizophyllaceae). A literature review. International Journal of Medicinal Mushrooms, 7(1and2).
• Hoey, M. T., and Parks, C. R. (1991). Isozyme divergence between eastern Asian, north American, and Turkish species of Liquidambar (Hamamelidaceae). American Journal of Botany, 78(7), 938-947.
• Karahancı, O. N., Öztoprak, Ü. Y., Ersoy, M., Ünsal, Ç. Z., Hayırlıdağ, M., and Büken, N. Ö. (2015). Geleneksel ve tamamlayıcı tıp uygulamaları yönetmeliği ile yönetmelik taslağının karşılaştırılması. Türkiye Biyoetik Dergisi, 2(2), 117-26.
• Khojimatov, O. K., Gafforov, Y., and Bussmann, R. W. (Eds.). (2023). Ethnobiology of Uzbekistan: Ethnomedicinal Knowledge of Mountain Communities (pp. 107-159). Berlin/Heidelberg, Germany: Springer.
• Kotowski, M. A. (2019). History of mushroom consumption and its impact on traditional view on mycobiota–an example from Poland. Microbial Biosystems, 4(3), 1-13.
• Lee, K. H., Morris-Natschke, S. L., Yang, X., Huang, R., Zhou, T., Wu, S. F., and Itokawa, H. (2012). Recent progress of research on medicinal mushrooms, foods, and other herbal products used in traditional Chinese medicine. Journal of Traditional and Complementary Medicine, 2(2), 1-12.
• Liu, Q., An, X., Chen, Y., Deng, Y., Niu, H., Ma, R., and Wang, M. (2022). Effects of Auricularia auricula polysaccharides on gut microbiota and metabolic phenotype in mice. Foods, 11(17), 2700.
• Lovy, A., Knowles, B., Labbe, R., and Nolan, L. (2000). Activity of edible mushrooms against the growth of human T4 leukemic cancer cells, HeLa cervical cancer cells, and Plasmodium falciparum. Journal of herbs, spices and medicinal plants, 6(4), 49-57.
• Ming, A. (1996). Chinese-English manual of common-used in traditional Chinese medicine. Guangdong, China: Publishing House of Guangdong Science and Technology.
• Mollahaliloğlu, S., Uğurlu, F. G., Kalaycı, M. Z., and Öztaş, D. (2015). The new period in traditional and complementary medicine. Ankara Medical Journal; Vol 15, No 2 (2015).
• Moser, M., (1983). Keys to Agarics and Boleti. Gustav Fiscer Verlag, Stuttart. 535.
• Ogawa, K., and Yashima, T. (2021). Enhanced water uptake in the longitudinal direction by shiitake mycelium in shiitake cultivation logs: increase in effective diffusion coefficient based on mass of liquid water uptake. Wood science and technology, 55(5), 1237-1267.
• Ooi, V. E., and Liu, F. (2000). Immunomodulation and anti-cancer activity of polysaccharide-protein complexes. Current medicinal chemistry, 7(7), 715-729.
• Phillips, R. (1981). Mushrooms and Other Fungi of Great Britain and Europe. Pan Books Ltd., London. 287.
• Ray, P., Kundu, S., and Paul, D. (2024). Exploring the Therapeutic Properties of Chinese Mushrooms with a Focus on their Anti-Cancer Effects: A Systemic review. Pharmacological Research-Modern Chinese Medicine, 100433.
• Sevindik, M. (2018). Investigation of antioxidant/oxidant status and antimicrobial activities of Lentinus tigrinus. Advances in Pharmacological and Pharmaceutical Sciences, 2018(1), 1718025.
• Stamets, P. (2000). Growing gourmet and medicinal mushrooms. Ten speed press.
• Vu, V., Muthuramalingam, K., Singh, V., Choi, C., Kim, Y. M., Unno, T., and Cho, M. (2022). Schizophyllum commune-derived β-glucan improves intestinal health demonstrating protective effects against constipation and common metabolic disorders. Applied Biological Chemistry, 65(1), 9.
• Wang, L., Li, J. Q., Zhang, J., Li, Z. M., Liu, H. G., and Wang, Y. Z. (2020). Traditional uses, chemical components and pharmacological activities of the genus Ganoderma P. Karst.: a review. RSC advances, 10(69), 42084-42097.
• Wasser, S. J. A. M. B. (2002). Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides. Applied microbiology and biotechnology, 60, 258-274.
• Wasser, S. P. (2005). Shiitake (Lentinus edodes). Encyclopedia of dietary supplements, 653-664.
• Wasson, R. G. (1957). Seeking the magic mushroom. Life, 42(19), 100-120.
• Yuan, Y., Wang, Y. J., Sun, G. P., Wang, Y. R., Cao, L. J., Shen, Y. M., and Huang, L. Q. (2018). Archaeological evidence suggests earlier use of Ganoderma in Neolithic China. Chin. Sci. Bull, 63(13), 1180-1188.
• Zhao, Y., Wang, L., Zhang, D., Li, R., Cheng, T., Zhang, Y., and Gao, S. (2019). Comparative transcriptome analysis reveals relationship of three major domesticated varieties of Auricularia auricula-judae. Scientific reports, 9(1), 78.
• Zhu, X. L., Chen, A. F., and Lin, Z. B. (2007). Ganoderma lucidum polysaccharides enhance the function of immunological effector cells in immunosuppressed mice. Journal of ethnopharmacology, 111(2), 219-226.
• Zong, X., Zhang, H., Zhu, L., Deehan, E. C., Fu, J., Wang, Y., and Jin, M. (2023). Auricularia auricula polysaccharides attenuate obesity in mice through gut commensal Papillibacter cinnamivorans. Journal of Advanced Research, 52, 203-218.