Hydroxyapatite crystallization in the presence of pentanoic acid

Abstract

The effect of pentanoic acid, an important fatty acid, on hydroxyapatite crystallization was investigated in this study. The crystallization experiments were performed in pure media and in the presence of three different pentanoic acid concentrations as 100, 500 and 1000 ppm in a batch system. The hydroxyapatite crystals obtained were characterized by XRD, SEM, particle size, BET, FTIR, zeta potential and TG analysis techniques. Compared to pure media, the particle size of the hydroxyapatite obtained in pentanoic acid media increased, significant changes in crystal morphology were determined. The results of FTIR showed that pentanoic acid used as the additive adsorbed onto the surface of the hydroxyapatite crystals and this result was supported by zeta potential measurements. While the zeta potential of hydroxyapatite crystals obtained in pure media was -20.9 ± 1.1 mV, this value was + 2.1 ± 1.3 mV for 1000 ppm pentanoic acid media. In addition, the thermal decomposition kinetics of hydroxyapatite crystal was investigated using Kissinger and Coats-Redfern models. The average activation energy value for the decomposition of crystals was 538.51 kJ / mol. This value was calculated as 580.99 kJ / mol for crystals obtained in pentanoic acid media. According to the Coats Redfern kinetic model, the 3D diffusion model was determined to be the best model to characterize the thermal decomposition behavior of the hydroxyapatite crystals.

Keywords

• Hydroxyapatite,crystallization,pentanoic acid,characterization

Hidroksiapatit kristalizasyonunun pentanoik asit varlığında incelenmesi

Abstract

Bu çalışmada önemli bir yağ asidi olan pentanoik asidin hidroksiapatit kristalizasyonu üzerine olan etkisi incelenmiştir. Bu amaçla kristalizasyon deneyleri saf ortamda ve 100, 500 ve 1000 ppm olmak üzere üç farklı pentanoik asit konsantrasyonunda kesikli bir sistemde yürütülmüştür. Elde edilen hidroksiapatit kristalleri, XRD, SEM, tane boyutu, BET, FTIR, zeta potansiyeli ve TG analiz yöntemleri kullanılarak karakterize edilmiştir. Pentanoik asit varlığında, hidroksiapatit kristallerin ortalama tane boyutunun saf ortama göre arttığı, kristal morfolojisinde önemli değişiklikler meydana geldiği belirlenmiştir. FTIR analiz sonuçları, katkı maddesi olarak kullanılan pentanoik asidin kristal yüzeyine tutunduğunu göstermiş ve bu sonuçlar zeta potansiyeli ölçümleri ile desteklenmiştir. Saf ortamda üretilen hidroksiapatit kristallerinin zeta potansiyeli -20,9±1,1 mV iken kristallerin yüzey yükleri 1000 ppm pentanoik asit konsantrasyonunda +2,1±1,3 mV değerine ulaşmıştır. Ayrıca hidroksiapatit kristallerinin termal bozunma kinetiği Kissinger ve Coats-Redfern yöntemleri kullanılarak incelenmiştir. Saf ortamda elde edilen hidroksiapatit kristallerinin termal bozunması sırasında gerekli olan ortalama aktivasyon enerjisi Kissinger modeli kullanılarak 538,51 kJ/mol olarak belirlenmiştir. Bu değer pentanoik asit ortamında üretilen kristaller için ise 580,99 kJ/mol olarak hesaplanmıştır. Coats Redfern kinetik modeline göre hem saf hem de katkı ortamı için 3D difüzyon modelinin hidroksiapatitin termal bozunma sürecini en iyi karakterize eden mekanizma olduğu belirlenmiştir.

Keywords

• Hidroksiapatit,kristalizasyon,pentanoik asit,karakterizasyon

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