Bovine Herpesvirus-1 (BHV-1) ve Subtipleri

Abstract

Sığırların Herpesvirus (BHV-1) enfeksiyonları, sığırlarda üst solunum yolu (Infectious Bovine Rhinotracheitis-IBR) ve genital kanal enfeksiyonu (Infectitious Pustuler Vulvovaginitis-IPV, Infectitious Pustuler Balanoposthitis-IPB)’na sebep olan bulaşıcı latent seyirli viral bir enfeksiyondur. BHV-1, sığırların yanısıra koyun, keçi gibi hayvan türlerinde ateş, solunum sayısının artması, öksürük, burun akıntısı (önce seröz daha sonra mukopurulent), burun mukozasında hiperemi, bazen konjuktivitis, salya artışı, anoreksi, süt veriminde azalma gibi klinik bulgulara yol açabilen dünya çapında oldukça yaygın bir patojendir. Ülkemizde geçmiş yıllarda yapılan virolojik ve serolojk çalışmalarda bu virusun yaygınlığı belirlenmiştir. Ancak virusun moleküler karakterizasyonu ve subtiplendirilmesi ile ilgili çok az çalışma bulunmaktadır. Bu derlemede BHV-1 ve subtiplendirilmesi hakkında detaylı bilgiler sunulmuştur.

Keywords

• Bovine Herpesvirus
• sığır
• subtiplendirme
• latent enfeksiyon

Bovine Herpesvirus-1 (BHV-1) and Subtypes

Abstract

Bovine Herpesvirus (BHV-1) is a latent viral infection that causes upper respiratory tract (Infectious Bovine Rhinotracheitis-IBR) and genital canal infection (Infectious Pustuler Vulvovaginitis-IPV, Infectious Pustuler Balanoposthitis-IPB) in cattle. BHV may cause clinical symptoms such as fever, increased respiratory rate, cough, runny nose (first serous then mucopurulent), hyperemia in nasal mucosa, sometimes conjunctivitis, increased saliva, anorexia, decreased milk yield in cattle, as well as sheep and goats, it is a common pathogen worldwide. The prevalence of this virus has been determined in virological and serological studies in our country in the past years. However, there are very few studies on molecular characterization and subtyping of the virus. In this review, detailed information about BHV-1 and its subtyping is presented.

Keywords

• Bovine Herpesvirus
• cattle
• subtyping
• latent infection

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