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Caralluma tuberculata - Korunması gereken önemli bir tıbbi bitki

Year 2019, Volume: 12 Issue: 1, 189 - 196, 15.04.2019
https://doi.org/10.5505/biodicon.2019.29392

Abstract

Caralluma tuberculata çok yıllık bir bitkidir. Pakistan'ın en çok dağlık bölgelerinde bulunan Asclepiadaceae familyasına aittir. Bitki pişmiş halde, çay olarak tüketilmiş veya kuru toz halinde veya taze çiğnenmiş olarak kullanılır. Çok büyük bir tıbbi öneme sahiptir. Mide problemleri, diyabet, kas ağrısı, cilt tedavisi ve iştah açıcı gibi çeşitli rahatsızlıkları tedavi etmek için yıllarca halk hekimliği olarak birçok topluluk bu bitkiyi kullandı. Modern araştırmalar, çeşitli ilaçların formulasyonunda kullanılabileceğini göstermektedir. Bitki anti-kanser, anti-diyabetik, antioksidan, anti-mikrobiyal aktiviteler ve diğer rahatsızlıklar için test edilmiştir. Bitki sağlık yararları için korunmalıdır. Burada, bu önemli bitkinin tıbbi değerini kısaca tanımlamak ve topluluğun korunmasına ilişkin farkındalık yaratmak için çaba sarf edilmektedir.

References

  • Jaffri, S. M. (1966). Flora of Karachi. Karachi: The Book Corporation.
  • Meve, U., & Liede, S. (2004). Subtribal division of Ceropegieae (Apocynaceae Asclepiadoideae). Taxon, 53, 61-72.
  • Saxena, A. K., & Sarbhai, R. P. (1975). A Text Book of Botany. High Court Road, Kitab Ghar: Oxford Press.
  • Sattar, E. A. (2009). Antiplasmodial and antitrypanosomal activity of plants from the Kingdom of Saudi Arabia. J. Nat. Med., 63, 232-239.
  • Adnan, M., Jan, S., Mussarat, S., Tariq, A., Begum, S., Afroz, A., & Shinwari, Z. K. (2014). A review on ethnobotany, phytochemistry and pharmacology of plant genus Caralluma R.Br. Journal of Pharmacy and Pharmacology, 66(10), 1351-1368.
  • Mustafa, K. A. (2014). Report on ‘Domestication of wild Caralluma tuberculata’. Department of Botany, Kohat Univeristy of Science and Technology, Kohat, Pakistan.
  • Ahmad, B., Abbas, S. J., Hussain, F., Bashir, S., & Ahmad, D. (2014). Study on Caralluma tuberculata nutritional composition and its importance as medicinal plant. Pak. J. Bot., 46(5), 1677-1684.
  • Lokhande, R. (2010). Study of some Indian medicinal plants by application of INAA and AAS techniques. Natural Science, 02, 26-32.
  • Adnan, M., Hussain, J., Shah, M. T., Shinwari, Z. K., Ullah, F., Bahader, A., ... Watanabe, T. (2010). Proximate and nutrient composition of medicinal plants of humid and sub-humid regions in North-west Pakistan. Journal of Medicinal Plants Research, 4(4), 339-345.
  • Seiler, H. G., Sigel, A., & Sigel, H. (1994). Handbook on metals in clinical and analytical chemistry. Marcel Dekker Incorporated.
  • Bader, A., Braca, A., Tommasi, N. D., & Morelli, I. (2003). Further constituents from Caralluma negevensis. Phytochemistry, 62, 1277-1281.
  • Bensuzan, K. (2009). Taxonomy and conservation status of Moroccan stapeliads (Apocynaceae Asclepiadoideae-Ceropegieae Stapeliinae). Bulletin de l’Institut Scientifique, Rabat, section Sciences de la Vie, 31, 67-77.
  • Formisano, C., Senatore, F., & Porta, G. D. (2009). Headspace volatile composition of the flowers of Caralluma europaea N.E.Br. (Apocynaceae). Molecules, 14, 4597-4613.
  • Waheed, A., Barker, J., Barton, S. J., & Khan, G. M. (2011). Novel acylated steroidal glycosides from Caralluma tuberculata induce caspase dependent apoptosis in cancer cells. J. Ethnopharmacol., 137, 1189-1196.
  • Ahmed, S., Owen, C. P., Waheed, A., Nisa, S., Bibic, Y., & Chaudhary, M. F. (2009). Biochemical evaluation of extracts from Caralluma tuberculata against hormone-dependent breast cancer cells. Journal of Pharmacy and Pharmacology, 61(S1), A135.
  • Rizwani, G. H. (1991). Phytochemical and biological studies on medicinal herbs, C. tuberculata and C. edulis. Ph D thesis, Department of Pharmacogonosy, Faculty of Pharmacy, University of Karachi.
  • Rauf, A., Muhammad, N., Barkatullah, Khan H., & Abbas, H. F. (2013). Antinociceptive, sedative and muscle relaxants activity of Caralluma tuberculata N.E. Brown. Orthop. Muscul. Syst., 2, 131.
  • Rauf. A., Rahman, W., Jan, M. R., & Muhammad, N. (2013). Phytochemical, phytotoxic and antioxidant profile of Caralluma tuberculata N.E. Brown Wudpecker. Journal of Pharmacy and Pharmacology, 2(2), 021-025.
  • Oyama, M., Ibrahim, I., Toshiyuki, T., Munekazu, I. et al. (2007). Five new steroidal glycosides from Caralluma dalzielii. Helv. Chim. Acta, 90, 63-71.
  • Venkatesh, S., Reddy, G. D., Reddy, B. M., Ramesh, M., Rao, A. V. N. (2003). Anti-hyperglycemic activities of Caralluma attenuate. Fitoterapia, 74, 274-279.
  • Ahmed, M. M., & Shaikh, M. M. (1989). Improvement in glucose tolerance by Caralluma tuberculata, Acacia nilotica and Papaver somniferum alcoholic extract. Pak. J. Zool., 21, 325332.
  • Durrani, M. J., Manzoor, M., & Irfan, S. (2009). Folk uses of some plants of Quetta, Pakistan. Pak. J. Plant Sci., 15(1), 1-6.
  • Lawrence, R. M., & Choudhary, S. (2004). Caralluma fimbriata in the treatment of obesity. 12th annual congress on anti-aging medicine. Winter session December 2-5. Las Vegas NV, USA.
  • Tareen, R. B., Bibi, T., Khan, M. A., Ahmad, M., & Zafar, M. (2010). Indigenous knowledge of folk medicine by the women of Kalat and Khuzdar regions of Balochistan, Pakistan. Pak. J. Bot., 42, 1465-1485.
  • Ramesh, M., Nageshwwr, Y. R., Rao, A. N. N., Prbhakar, M. C., Rao, C. S., Muralidhar, N., & Reddy, B. M. (1998). Anti-nociceptive and anti-inflammatory activity of a flavonoid isolated from Caralluma attenuata. Journal of Ethnopharmacology, 62, 63-66.
  • Safa, O., Soltanipoor, Ma., & Rastegar, S. (2013). An ethnobotanical survey on Hormozgan Province, Iran. Avicenna J. Phytomed., 3, 64-81.
  • Shah, A., Marwat, S. K., Gohar, F., & Khan, A. (2013). Ethnobotanical study of medicinal plants of semi-tribal area of Makerwal & Gulla Khel (lying between Khyber Pakhtunkhwa and Punjab Provinces), Pakistan. Am. J. Plant Sci., 4, 98-116.
  • Yahya, M. A., Mossa J. S., Al-Mashal I. A., Tariq, M., & Al-Badr, A. A. (1984). Phytochemical and Biological studies on Saudi plants. Vol. 3, Reports submitted to Saudi National Center for Science and Technology.
  • Ozturk, M., Altay, V., Latiff, A., Asad Ziaee, M., Choudhry, M. I., Shaheen, F., & Durmuşkahya, C. (2018). A Comparative Analysis of the Medicinal Plants Used for Diabetes Mellitus in the Traditional Medicine in Turkey, Pakistan and Malaysia. In: Ozturk, M. & Hakeem, K. H. (eds.), Plant and Human Health, Volume 1, Chapter 11, Ethnobotany and Physiology: Springer Nature, pp. 409-461.
  • Kumar, A. S., Kavimani, S., & Jayaveera, K. N. (2011). A review on medicinal plants with potential anti diabetic activity. Int. J. Phytopharmacol., 2, 53-60.
  • Wadood, A., Wadood, N., & Shah, S. A. (1989). Effect of Acacia arabica and Caralluma edulis on blood glucose levels of normal and allox a diabetic rabbits. J. Pak. Med. Assoc., 9, 208-212.
  • Manzoor, M., Ayesha, A., & Durrani, M. J. (2013). Uses of fruits, vegetables and herbs for the treatment of diabetes by the people of Quetta city. Sci. Technol. Dev., 32, 24-27.
  • Najam-us-Saqib, Q., Rahila Qayyum, R., & Abdul Waheed, A. (2013). Acute and chronic toxicity study of ethyl acetate fraction of Caralluma tuberculata in mice. International Journal of Pharmacology and Clinical Sciences, 2(4), 99-104.
  • Sultan, K., Zakir, M., Khan, H., Khan, I. U., Rehman, A., Akber, N. U., Muhammad, N., & Khan, M. A. (2014). The effect of extract/fractions of Caralluma tuberculata on blood glucose levels and body weight in alloxan-induced diabetic rabbits. Journal of Evidence-Based Complementary & Alternative Medicine, 19(3), 195-199.
  • Poodineh, J., Feizabad, A. K., & Nakhaee, A. (2015). Antioxidant activities of Caralluma tuberculata on Streptozotocin-Induced Diabetic Rats. Drug Development Research, 76, 40-47.
  • Ozturk, M., Altay, V., Latiff, A., Shareef, S., Shaheen, F., & Choudhry, M. I. (2018). Potential Medicinal Plants Used in the Hypertension in Turkey, Pakistan and Malaysia. In: Ozturk, M., & Hakeem, K. R. (eds.), Plant and Human Health, Volume 1, Ethnobotany and Physiology. Chapter 16, Springer Nature, Springer Nature, pp. 595-618.
  • Karuppusamy, S. (2007). Medicinal plants used by Palyan tribe of Sirumalai Hills of Southern India. Nat. Prod. Radiance, 6, 436-442.
  • Marwat, S. K., Marwat, S. K., & Khan, I. U. (2012). Tracing the useful ethno phyto-medicinal recipes of angiosperms used against jaundice and hepatitis in Indo-Pak subcontinent. World Appl. Sci. J., 18, 1243-1252.
  • Al-Yahya, M. A., Abdel-Sattar, E., & Guittet, E. (2000). Pregnane glycosides from Caralluma russeliana. J. Nat. Prod., 63, 1451-1453.
  • Naik, R. M., Vaishnavi, V., & Preethi, K. (2012). Nutritive value and mineral composition of edible Caralluma and Boucerosia species from the arid areas of Karnataka. Int. J. Agric. Environ. Biotechnol., 5, 117-125.
  • Shinwari, Z. K., Rehman, M., Watanabe, T., & Yoshikawa, Y. (2006). Medicinal and aromatic plants of Pakistan (A Pictorial Guide). Kohat University of Science and Technology, Kohat, Pakistan.
  • Ali, H., Sannai, J., Sher, H., & Rashid, A. (2011). Ethnobotanical profile of some plant resources in Malam Jabba valley of Swat, Pakistan. J. Med. Plants Res., 5, 4676-4687.
  • Ahmad, R., Sheikh, T. U., Ahmed, A., & Ahmad, M. (1993). Medicinal importance of essential oils. Hamdard Medicus, 36, 101-115.
  • Ozturk, M., & Hakeem, K. R. (2018). Plant and Human Health-Volume 1. Ethnobotany and Physiology. Springer Nature.
  • Altay, V., Karahan, F., Sarcan, Y. B., & İlçim, A. (2015). An ethnobotanical research on wild plants sold in Kırıkhan district (Hatay/Turkey) herbalists and local markets. Biological Diversity and Conservation, 8(2), 81-91.
  • Altay, V., Karahan, P., Karahan, F., & Öztürk, M. (2018). Pollen analysis of honeys from Hatay/Turkey. Biological Diversity and Conservation, 11(3), 209-222.
  • Karahan F., & İlçim, A. (2017). The potential benefits of medicinal and aromatic plants in cancer patients undergoing radiotherapy. Biological Diversity and Conservation, 10(2), 51-61.
  • Raftery, L., & Goldberg, R. M. (2010). Optimal delivery of cytotoxic chemotherapy for colon cancer. Cancer J., 16(3), 214-219.
  • Ashwini, S., Ezhilarasan, D., & Anitha, R. (2017). Cytotoxic effect of Caralluma fimbriata against human colon cancer cells. Pharmacogn. J., 9(2), 204-207.
  • Zito, P., Sajeva, M., Bruno, M., Maggio, A., & Rosselli, S. (2010). Essential oil composition of stems and fruits of Caralluma europaea N.E.Br. (Apocynaceae). Molecules, 15, 627-638.
  • Abdel-Sattar, E., Hossam, M. A., Alaa, K., Abdel-Naim, A. B., & ShehataI, A. (2013). Anti-hyperglycemic activity of Caralluma tuberculata in streptozotocin-induced diabetic rats. Food Chem. Toxicol., 59, 111-117.
  • Raziq, N., Raziq, N., Naveed Muhammad, N., Kamran Ahmad Chishti, K. A., Saeed, M., Rahman, S., & Khan, H. (2011). Correlation of the antioxidant capacity with the phenolic contents of Hypericum monogynum and Hypericum perforatum. Afr. J. Pharm. Pharmacol., 5, 1872-1876.
  • Vajha, M., Amrutha, V., & Audipudi, M. K. S. R. (2010). Evaluation of immune stimulating activities of Caralluma species. Int. J. Pharmacognosy Phytochem. Res., 2, 1-4.
  • Kulkarni, A., Vaishali, S. M., Suchita, P., & Gadekar, A. S. (2012). Evaluation of antibacterial activity of Caralluma adscendens Roxb. Stem. Int. Res. J. Pharm., 3(9), 269-270.
  • Abdel-Sattar, E., Harraz, F. M., Al-Ansari, S. M., El-Mekkawy, S., Ichino, C., Kiyohara, H., Otoguro, K., Omura, S., & Yamada, H. (2009). Antiplasmodial and antitrypanosomal activity of plants from the Kingdom of Saudi Arabia. Journal of Natural Medicines, 63(2), 232-239.
  • Deepak, D., Khare, A., & Khare, M. P. (1989). Plant Pregnanes. Phytochemistry, 28, 3255-3263.
  • Kuppusamy, P., Yusoff, M. M., Maniam, G. P., Ichwan, S. J., Soundharrajan, I., & Govindan, N. (2014). Nutraceuticals as potential therapeutic agents for colon cancer: A review. Acta Pharm. Sin. B., 4(3), 173-181.
  • Priya, D., Rajaram, K., & Kumar, P. S. (2011). Phytochemical studies and GCMS analysis of Caralluma fimbriata Wall. Int. J. Pharm. Res. Dev., 10, 105-110.
  • Shinwari, A., Khan, A., & Nakaike, T. (eds) (2003). Medicinal and other useful plants of District Swat. WWF Pakistan.
  • Hussain, W. (2012). Tradable and conservation status of medicinal plants of Kurram Valley, Parachinar, Pakistan. J. Appl. Pharma. Sci., 2, 66-70.
  • Shinwari, Z. K., Gilani, S. S., & Shaukat, M. (2002). Ethnobotanical resources and implication for curriculum. In: Shinwari, Z. K., Hamilto, A., & Khan, A. A. (eds.), Proceeding of workshop on curriculum development in Applied Ethnobotany. WWF Pakistan, pp. 21-34.
  • Ramakrishnan, R., Periyasamy, R., Lakkakula, S., Subramani, P., Arockiam, S. R. et al. (2017). In vitro propagation and conservation of useful endangered medicinal plants with anticancer activity. J. Mol. Biol. Biotech., 2(3), 8.

Caralluma tuberculata - An important medicinal plant to be conserved

Year 2019, Volume: 12 Issue: 1, 189 - 196, 15.04.2019
https://doi.org/10.5505/biodicon.2019.29392

Abstract

Caralluma tuberculata N.E. Brown is a perennial herb. It belongs to Asclepiadaceae family, mostly found in the mountainous regions of Pakistan. The plant is used as vegetable in cooked form, consumed as tea or used in the dry powder form or chewed fresh. It is of great medicinal importance. Many communities have used this plant - as folk medicine for years to cure various ailments such as stomach problems, diabetes, muscle pain and skin treatment and as appetizer. Modern research suggests that it can be used in the formulation of various drugs. The plant has been tested for its anticancer, anti-diabetic, antioxidant, antimicrobial activities and other ailments. The plant must be conserved for its health benefits. An effort is made here to briefly describe the medicinal value of this important plant and create awareness in the community regarding its conservation.

References

  • Jaffri, S. M. (1966). Flora of Karachi. Karachi: The Book Corporation.
  • Meve, U., & Liede, S. (2004). Subtribal division of Ceropegieae (Apocynaceae Asclepiadoideae). Taxon, 53, 61-72.
  • Saxena, A. K., & Sarbhai, R. P. (1975). A Text Book of Botany. High Court Road, Kitab Ghar: Oxford Press.
  • Sattar, E. A. (2009). Antiplasmodial and antitrypanosomal activity of plants from the Kingdom of Saudi Arabia. J. Nat. Med., 63, 232-239.
  • Adnan, M., Jan, S., Mussarat, S., Tariq, A., Begum, S., Afroz, A., & Shinwari, Z. K. (2014). A review on ethnobotany, phytochemistry and pharmacology of plant genus Caralluma R.Br. Journal of Pharmacy and Pharmacology, 66(10), 1351-1368.
  • Mustafa, K. A. (2014). Report on ‘Domestication of wild Caralluma tuberculata’. Department of Botany, Kohat Univeristy of Science and Technology, Kohat, Pakistan.
  • Ahmad, B., Abbas, S. J., Hussain, F., Bashir, S., & Ahmad, D. (2014). Study on Caralluma tuberculata nutritional composition and its importance as medicinal plant. Pak. J. Bot., 46(5), 1677-1684.
  • Lokhande, R. (2010). Study of some Indian medicinal plants by application of INAA and AAS techniques. Natural Science, 02, 26-32.
  • Adnan, M., Hussain, J., Shah, M. T., Shinwari, Z. K., Ullah, F., Bahader, A., ... Watanabe, T. (2010). Proximate and nutrient composition of medicinal plants of humid and sub-humid regions in North-west Pakistan. Journal of Medicinal Plants Research, 4(4), 339-345.
  • Seiler, H. G., Sigel, A., & Sigel, H. (1994). Handbook on metals in clinical and analytical chemistry. Marcel Dekker Incorporated.
  • Bader, A., Braca, A., Tommasi, N. D., & Morelli, I. (2003). Further constituents from Caralluma negevensis. Phytochemistry, 62, 1277-1281.
  • Bensuzan, K. (2009). Taxonomy and conservation status of Moroccan stapeliads (Apocynaceae Asclepiadoideae-Ceropegieae Stapeliinae). Bulletin de l’Institut Scientifique, Rabat, section Sciences de la Vie, 31, 67-77.
  • Formisano, C., Senatore, F., & Porta, G. D. (2009). Headspace volatile composition of the flowers of Caralluma europaea N.E.Br. (Apocynaceae). Molecules, 14, 4597-4613.
  • Waheed, A., Barker, J., Barton, S. J., & Khan, G. M. (2011). Novel acylated steroidal glycosides from Caralluma tuberculata induce caspase dependent apoptosis in cancer cells. J. Ethnopharmacol., 137, 1189-1196.
  • Ahmed, S., Owen, C. P., Waheed, A., Nisa, S., Bibic, Y., & Chaudhary, M. F. (2009). Biochemical evaluation of extracts from Caralluma tuberculata against hormone-dependent breast cancer cells. Journal of Pharmacy and Pharmacology, 61(S1), A135.
  • Rizwani, G. H. (1991). Phytochemical and biological studies on medicinal herbs, C. tuberculata and C. edulis. Ph D thesis, Department of Pharmacogonosy, Faculty of Pharmacy, University of Karachi.
  • Rauf, A., Muhammad, N., Barkatullah, Khan H., & Abbas, H. F. (2013). Antinociceptive, sedative and muscle relaxants activity of Caralluma tuberculata N.E. Brown. Orthop. Muscul. Syst., 2, 131.
  • Rauf. A., Rahman, W., Jan, M. R., & Muhammad, N. (2013). Phytochemical, phytotoxic and antioxidant profile of Caralluma tuberculata N.E. Brown Wudpecker. Journal of Pharmacy and Pharmacology, 2(2), 021-025.
  • Oyama, M., Ibrahim, I., Toshiyuki, T., Munekazu, I. et al. (2007). Five new steroidal glycosides from Caralluma dalzielii. Helv. Chim. Acta, 90, 63-71.
  • Venkatesh, S., Reddy, G. D., Reddy, B. M., Ramesh, M., Rao, A. V. N. (2003). Anti-hyperglycemic activities of Caralluma attenuate. Fitoterapia, 74, 274-279.
  • Ahmed, M. M., & Shaikh, M. M. (1989). Improvement in glucose tolerance by Caralluma tuberculata, Acacia nilotica and Papaver somniferum alcoholic extract. Pak. J. Zool., 21, 325332.
  • Durrani, M. J., Manzoor, M., & Irfan, S. (2009). Folk uses of some plants of Quetta, Pakistan. Pak. J. Plant Sci., 15(1), 1-6.
  • Lawrence, R. M., & Choudhary, S. (2004). Caralluma fimbriata in the treatment of obesity. 12th annual congress on anti-aging medicine. Winter session December 2-5. Las Vegas NV, USA.
  • Tareen, R. B., Bibi, T., Khan, M. A., Ahmad, M., & Zafar, M. (2010). Indigenous knowledge of folk medicine by the women of Kalat and Khuzdar regions of Balochistan, Pakistan. Pak. J. Bot., 42, 1465-1485.
  • Ramesh, M., Nageshwwr, Y. R., Rao, A. N. N., Prbhakar, M. C., Rao, C. S., Muralidhar, N., & Reddy, B. M. (1998). Anti-nociceptive and anti-inflammatory activity of a flavonoid isolated from Caralluma attenuata. Journal of Ethnopharmacology, 62, 63-66.
  • Safa, O., Soltanipoor, Ma., & Rastegar, S. (2013). An ethnobotanical survey on Hormozgan Province, Iran. Avicenna J. Phytomed., 3, 64-81.
  • Shah, A., Marwat, S. K., Gohar, F., & Khan, A. (2013). Ethnobotanical study of medicinal plants of semi-tribal area of Makerwal & Gulla Khel (lying between Khyber Pakhtunkhwa and Punjab Provinces), Pakistan. Am. J. Plant Sci., 4, 98-116.
  • Yahya, M. A., Mossa J. S., Al-Mashal I. A., Tariq, M., & Al-Badr, A. A. (1984). Phytochemical and Biological studies on Saudi plants. Vol. 3, Reports submitted to Saudi National Center for Science and Technology.
  • Ozturk, M., Altay, V., Latiff, A., Asad Ziaee, M., Choudhry, M. I., Shaheen, F., & Durmuşkahya, C. (2018). A Comparative Analysis of the Medicinal Plants Used for Diabetes Mellitus in the Traditional Medicine in Turkey, Pakistan and Malaysia. In: Ozturk, M. & Hakeem, K. H. (eds.), Plant and Human Health, Volume 1, Chapter 11, Ethnobotany and Physiology: Springer Nature, pp. 409-461.
  • Kumar, A. S., Kavimani, S., & Jayaveera, K. N. (2011). A review on medicinal plants with potential anti diabetic activity. Int. J. Phytopharmacol., 2, 53-60.
  • Wadood, A., Wadood, N., & Shah, S. A. (1989). Effect of Acacia arabica and Caralluma edulis on blood glucose levels of normal and allox a diabetic rabbits. J. Pak. Med. Assoc., 9, 208-212.
  • Manzoor, M., Ayesha, A., & Durrani, M. J. (2013). Uses of fruits, vegetables and herbs for the treatment of diabetes by the people of Quetta city. Sci. Technol. Dev., 32, 24-27.
  • Najam-us-Saqib, Q., Rahila Qayyum, R., & Abdul Waheed, A. (2013). Acute and chronic toxicity study of ethyl acetate fraction of Caralluma tuberculata in mice. International Journal of Pharmacology and Clinical Sciences, 2(4), 99-104.
  • Sultan, K., Zakir, M., Khan, H., Khan, I. U., Rehman, A., Akber, N. U., Muhammad, N., & Khan, M. A. (2014). The effect of extract/fractions of Caralluma tuberculata on blood glucose levels and body weight in alloxan-induced diabetic rabbits. Journal of Evidence-Based Complementary & Alternative Medicine, 19(3), 195-199.
  • Poodineh, J., Feizabad, A. K., & Nakhaee, A. (2015). Antioxidant activities of Caralluma tuberculata on Streptozotocin-Induced Diabetic Rats. Drug Development Research, 76, 40-47.
  • Ozturk, M., Altay, V., Latiff, A., Shareef, S., Shaheen, F., & Choudhry, M. I. (2018). Potential Medicinal Plants Used in the Hypertension in Turkey, Pakistan and Malaysia. In: Ozturk, M., & Hakeem, K. R. (eds.), Plant and Human Health, Volume 1, Ethnobotany and Physiology. Chapter 16, Springer Nature, Springer Nature, pp. 595-618.
  • Karuppusamy, S. (2007). Medicinal plants used by Palyan tribe of Sirumalai Hills of Southern India. Nat. Prod. Radiance, 6, 436-442.
  • Marwat, S. K., Marwat, S. K., & Khan, I. U. (2012). Tracing the useful ethno phyto-medicinal recipes of angiosperms used against jaundice and hepatitis in Indo-Pak subcontinent. World Appl. Sci. J., 18, 1243-1252.
  • Al-Yahya, M. A., Abdel-Sattar, E., & Guittet, E. (2000). Pregnane glycosides from Caralluma russeliana. J. Nat. Prod., 63, 1451-1453.
  • Naik, R. M., Vaishnavi, V., & Preethi, K. (2012). Nutritive value and mineral composition of edible Caralluma and Boucerosia species from the arid areas of Karnataka. Int. J. Agric. Environ. Biotechnol., 5, 117-125.
  • Shinwari, Z. K., Rehman, M., Watanabe, T., & Yoshikawa, Y. (2006). Medicinal and aromatic plants of Pakistan (A Pictorial Guide). Kohat University of Science and Technology, Kohat, Pakistan.
  • Ali, H., Sannai, J., Sher, H., & Rashid, A. (2011). Ethnobotanical profile of some plant resources in Malam Jabba valley of Swat, Pakistan. J. Med. Plants Res., 5, 4676-4687.
  • Ahmad, R., Sheikh, T. U., Ahmed, A., & Ahmad, M. (1993). Medicinal importance of essential oils. Hamdard Medicus, 36, 101-115.
  • Ozturk, M., & Hakeem, K. R. (2018). Plant and Human Health-Volume 1. Ethnobotany and Physiology. Springer Nature.
  • Altay, V., Karahan, F., Sarcan, Y. B., & İlçim, A. (2015). An ethnobotanical research on wild plants sold in Kırıkhan district (Hatay/Turkey) herbalists and local markets. Biological Diversity and Conservation, 8(2), 81-91.
  • Altay, V., Karahan, P., Karahan, F., & Öztürk, M. (2018). Pollen analysis of honeys from Hatay/Turkey. Biological Diversity and Conservation, 11(3), 209-222.
  • Karahan F., & İlçim, A. (2017). The potential benefits of medicinal and aromatic plants in cancer patients undergoing radiotherapy. Biological Diversity and Conservation, 10(2), 51-61.
  • Raftery, L., & Goldberg, R. M. (2010). Optimal delivery of cytotoxic chemotherapy for colon cancer. Cancer J., 16(3), 214-219.
  • Ashwini, S., Ezhilarasan, D., & Anitha, R. (2017). Cytotoxic effect of Caralluma fimbriata against human colon cancer cells. Pharmacogn. J., 9(2), 204-207.
  • Zito, P., Sajeva, M., Bruno, M., Maggio, A., & Rosselli, S. (2010). Essential oil composition of stems and fruits of Caralluma europaea N.E.Br. (Apocynaceae). Molecules, 15, 627-638.
  • Abdel-Sattar, E., Hossam, M. A., Alaa, K., Abdel-Naim, A. B., & ShehataI, A. (2013). Anti-hyperglycemic activity of Caralluma tuberculata in streptozotocin-induced diabetic rats. Food Chem. Toxicol., 59, 111-117.
  • Raziq, N., Raziq, N., Naveed Muhammad, N., Kamran Ahmad Chishti, K. A., Saeed, M., Rahman, S., & Khan, H. (2011). Correlation of the antioxidant capacity with the phenolic contents of Hypericum monogynum and Hypericum perforatum. Afr. J. Pharm. Pharmacol., 5, 1872-1876.
  • Vajha, M., Amrutha, V., & Audipudi, M. K. S. R. (2010). Evaluation of immune stimulating activities of Caralluma species. Int. J. Pharmacognosy Phytochem. Res., 2, 1-4.
  • Kulkarni, A., Vaishali, S. M., Suchita, P., & Gadekar, A. S. (2012). Evaluation of antibacterial activity of Caralluma adscendens Roxb. Stem. Int. Res. J. Pharm., 3(9), 269-270.
  • Abdel-Sattar, E., Harraz, F. M., Al-Ansari, S. M., El-Mekkawy, S., Ichino, C., Kiyohara, H., Otoguro, K., Omura, S., & Yamada, H. (2009). Antiplasmodial and antitrypanosomal activity of plants from the Kingdom of Saudi Arabia. Journal of Natural Medicines, 63(2), 232-239.
  • Deepak, D., Khare, A., & Khare, M. P. (1989). Plant Pregnanes. Phytochemistry, 28, 3255-3263.
  • Kuppusamy, P., Yusoff, M. M., Maniam, G. P., Ichwan, S. J., Soundharrajan, I., & Govindan, N. (2014). Nutraceuticals as potential therapeutic agents for colon cancer: A review. Acta Pharm. Sin. B., 4(3), 173-181.
  • Priya, D., Rajaram, K., & Kumar, P. S. (2011). Phytochemical studies and GCMS analysis of Caralluma fimbriata Wall. Int. J. Pharm. Res. Dev., 10, 105-110.
  • Shinwari, A., Khan, A., & Nakaike, T. (eds) (2003). Medicinal and other useful plants of District Swat. WWF Pakistan.
  • Hussain, W. (2012). Tradable and conservation status of medicinal plants of Kurram Valley, Parachinar, Pakistan. J. Appl. Pharma. Sci., 2, 66-70.
  • Shinwari, Z. K., Gilani, S. S., & Shaukat, M. (2002). Ethnobotanical resources and implication for curriculum. In: Shinwari, Z. K., Hamilto, A., & Khan, A. A. (eds.), Proceeding of workshop on curriculum development in Applied Ethnobotany. WWF Pakistan, pp. 21-34.
  • Ramakrishnan, R., Periyasamy, R., Lakkakula, S., Subramani, P., Arockiam, S. R. et al. (2017). In vitro propagation and conservation of useful endangered medicinal plants with anticancer activity. J. Mol. Biol. Biotech., 2(3), 8.
There are 62 citations in total.

Details

Primary Language English
Subjects Conservation and Biodiversity
Journal Section Review
Authors

Muhammad Azim Khan This is me

Maqsood Khan This is me

Omer Suha Uslu This is me

Publication Date April 15, 2019
Submission Date June 15, 2018
Acceptance Date April 15, 2019
Published in Issue Year 2019 Volume: 12 Issue: 1

Cite

APA Khan, M. A., Khan, M., & Uslu, O. S. (2019). Caralluma tuberculata - Korunması gereken önemli bir tıbbi bitki. Biological Diversity and Conservation, 12(1), 189-196. https://doi.org/10.5505/biodicon.2019.29392

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❖ Biological Diversity and Conservation/ Biyolojik Çeşitlilik ve Koruma
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