Insight into effects of Axillarin and Verbascoside isolated from Tanacetum alyssifolium and Plantago euphratica on probiotic properties of Lactobacillus acidophilus and Lactobacillus rhamnosus

Year 2020, Volume: 29 Issue: 1, 47 - 54, 30.06.2020

Nasip Ümran Turan Hasan Ufuk Çelebioğlu Hüseyin Akşit Recep Taş

https://doi.org/10.38042/biost.2020.29.01.06

Cited By: 1

Abstract

Phenolic compounds are found in the seeds, flowers, leaves, stems, branches, and fruits of plants. They have an important place in human nutrition as many fruits and vegetables have phenolic compounds. Recently, many phenolic compounds have been used as functional foods and research of new phenolic compounds that are candidate to become functional foods is ongoing. Probiotics which are beneficial microorganisms, are living microbes that benefit the host when taken in sufficient amounts and they have an important role in human gastrointestinal microbiota. The present study aims to investigate effects of Axillarin and Verbascoside, two phenolic compounds isolated from Tanacetum alyssifolium and Plantago euphratica, respectively, on two very common probiotic bacteria Lactobacillus acidophilus and Lactobacillus rhamnosus. For this, growth kinetics, auto-aggregation, and microbial adhesion to solvents, which are some critical properties of probiotics, were investigated. Axillarin and verbascoside showed significant improvement on growths of Lactobacillus acidophilus LA-5 and Lactobacillus rhamnosus GG depending on the dose. Auto-aggregation properties were enhanced by these phenolic compounds, even though surface hydrophobicities were decreased. In conclusion, the present study indicates that the vital conditions of the probiotics could be modulated by Axillarin and/or Verbascoside, consequently their adhesion and colonization capabilities could be altered.

Keywords

Aggregation, MATS assay, Phenolic compounds, Probiotics

References

• Akdemir, Z. Ş., Tatli, I. I., Bedir, E., & Khan, I. A. (2004). Iridoid and phenylethanoid glycosides from Verbascum lasianthum. Turkish Journal of Chemistry, 28(2), 227-234.
• Alasalvar, C., Grigor, J. M., Zhang, D., Quantick, P. C., & Shahidi, F. (2001). Comparison of Volatiles, Phenolics, Sugars, Antioxidant Vitamins, and Sensory Quality of DifferentColored Carrot Varieties. Journal of Agricultural and Food Chemistry, 49(3), 1410–1416.
• Alander, M., Korpela, R., Saxelin, M., Vilpponen-Salmela, T., Matilla-Sandholm, T., & Wright, A. (1997). Recovery of Lactobacillus rhamnosus GG from human colonic biopsies. Letters in Applied Microbiology, 24, 361–364.
• Arceusz, A., Wesolowski, M., & Konieczynski, P. (2013). Methods for Extraction and Determination of Phenolic Acids in Medicinal Plants: A Review. Natural Product Communications, 8(12), 1821-29.
• Arjmandi, B. H. (2014). The Role of Prebiotics and Probiotics in Human Health. Journal of Food & Nutritional Disorders, 1(2), 108.
• Avila, J. G., de Liverant, J. G., Martınez, A., Martınez, G., Munoz, J. L., Arciniegas, A., & de Vivar, A. R. (1999). Mode of action of Buddleja cordata verbascoside against Staphylococcus aureus. Journal of Ethnopharmacology, 66(1), 75-78.
• Balasundram, N., Sundram, K., & Samman, S. (2006). Phenolic compounds in plants and agri-industrial by-products: Antioxidant activity, occurrence, and potential uses. Food Chemistry, 99(1), 191–203.
• Bellon-Fontaine, M.-N., Rault, J., & van Oss, C.J. (1996) Microbial adhesion to solvents: a novel method to determine the electron-donor⁄ electron-acceptor or Lewis acid-base properties of microbial cells. Colloid Surface B, 7, 47–53.