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Effects of Second Trimester Maternal Hemoglobin Levels on Birth Weight and Birth Time

Year 2010, Volume: 2010 Issue: 3, 156 - 160, 01.03.2010
https://doi.org/10.5174/tutfd.2008.00910.3

Abstract

Objectives: The aim of our study is to investigate the effects of anemia at the second trimester on birth weight and birth time. Patients and Methods: The medical reports of 1116 pregnant women who attended and delivered at our clinic between January 2005 and October 2007 were analyzed retrospectively. The patients were divided into two groups as having <9 gr/dl hemoglobin or ≥9 gr/dl hemoglobin levels. The gestational and the perinatal outcomes of the normal and anemic groups were compared. Results: The age and the parity were higher in the non-anemic group than in the anemic pregnants. (p=0.03, p=0.001). There was no statistically significant difference in the mode of birth and gestational complications between the two groups. While there was no statistically significant difference in the gestational age at delivery and birth weight, prematurity and oligohydramnios ratios were significantly higher in the anemic group compared to the group with Hb>9 gr/dL (p=0.041, p=0.004, respectively). Conclusion: The anemia of second trimester is related with prematurity and increased rate of oligohydramnios. Iron supplementation should be given during pregnancy to improve pregnancy outcomes. Amaç: Bu çalışmanın amacı ikinci trimester anemisinin doğum ağırlığı ve doğum haftasına etkisini araştırmaktır. Hastalar ve Yöntemler: Ocak 2005 ve Ekim 2007 tarihleri arasında kliniğimizde takip edilen ve doğum yapan 1116 hastanın kayıtları retrospektif olarak incelendi. Hastalar ikinci trimester hemoglobin değerleri <9 gr/dl olanlar ve ≥9 gr/dl olmak üzere iki gruba ayrıldı. Anemik olan ve normal hemoglobin seviyelerine sahip gebelerin gebelik seyri ve perinatal sonuçları karşılaştırıldı. Bulgular: Anemik olmayan grupta yaş ve parite anemik gebelere kıyasla yüksekti (sırasıyla p=0.03, p=0.001). Gruplar arasında doğum şekilleri ve gestasyonel komplikasyonlar açısından anlamlı bir farklılık görülmedi. Ortalama doğum zamanı ve doğum kilosu açısından anlamlı bir farklılık görülmezken ikinci trimester anemisi olan grupta prematurite ve oligohidramnios oranı daha fazla görüldü ve bu fark istatistiksel olarak anlamlı bulundu (p=0.041, p=0.004). Sonuç: İkinci trimester anemisi prematürite ve artan oligohidramnios oranlarıyla ilişkili olabilmektedir. Gebelik sonuçlarını iyileştirmek için gebelik süresince demir desteği yapılmalıdır.

References

  • Hallberg L. Perspectives on nutritional iron deficiency. Annu Rev Nutr 2001;21:1-21.
  • Müngen E. Iron supplementation in pregnancy. J Perinat Med 2003;31:420-6.
  • Hallberg L. Results of surveys to assess iron status in Europe. Nutr Rev 1995;53:314-22.
  • Looker AC, Dallman PR, Carroll MD, Gunter EW, Johnson CL. Prevalence of iron deficiency in the United States. JAMA 1997;277:973-6.
  • DeMaeyer EM. Preventing and controlling iron deficiency anaemia through primary health care. Geneva: World Health Organization; 1989.
  • Di Renzo GC, Roura LC, European Association of Perinatal Medicine-Study Group on Preterm Birth. Guidelines for the management of spontaneous preterm labor. J Perinat Med 2006;34:359-66.
  • Ott WJ. Reevaluation of the relationship between amniotic fluid volume and perinatal outcome. Am J Obstet Gynecol 2005;192:1803-9.
  • Lee JI, Kang SA, Kim SK, Lim HS. A cross sectional study of maternal iron status of Korean women during pregnancy. Nutr Res 2002;22:1377-88.
  • Steer PJ. Maternal hemoglobin concentration and birth weight. Am J Clin Nutr 2000;71(5 Suppl):1285S-7S.
  • Levy A, Fraser D, Katz M, Mazor M, Sheiner E. Maternal anemia during pregnancy is an independent risk factor for low birthweight and preterm delivery. Eur J Obstet Gynecol Reprod Biol 2005;122:182-6.
  • Klebanoff MA, Shiono PH, Selby JV, Trachtenberg AI, Graubard BI. Anemia and spontaneous preterm birth. Am J Obstet Gynecol 1991;164:59-63.
  • Scholl TO, Hediger ML, Fischer RL, Shearer JW. Anemia vs iron deficiency: increased risk of preterm delivery in a prospective study. Am J Clin Nutr 1992;55:985-8.
  • Lee HS, Kim MS, Kim MH, Kim YJ, Kim WY. Iron status and its association with pregnancy outcome in Korean pregnant women. Eur J Clin Nutr 2006;60:1130-5.
  • Milman N, Agger AO, Nielsen OJ. Iron status markers and serum erythropoietin in 120 mothers and newborn infants. Effect of iron supplementation in normal pregnancy. Acta Obstet Gynecol Scand 1994;73:200-4.
  • Krafft A, Breymann C, Streich J, Huch R, Huch A. Hemoglobin concentration in multiple versus singleton pregnancies--retrospective evidence for physiology not pathology. Eur J Obstet Gynecol Reprod Biol 2001;99:184-7.
  • Graves BW, Barger MK. A "conservative" approach to iron supplementation during pregnancy. J Midwifery Womens Health 2001;46:159-66.
  • Keverenge-Ettyang GA, van Marken Lichtenbelt W, Esamai F, Saris W. Maternal nutritional status in pastoral versus farming communities of West Pokot, Kenya: differences in iron and vitamin A status and body composition. Food Nutr Bull 2006;27:228-35.
  • Shobeiri F, Begum K, Nazari M. A prospective study of maternal hemoglobin status of Indian women dur- ing pregnancy and pregnancy outcome. Nutr Res 2006;26:209-13.
  • Lu ZM, Goldenberg RL, Cliver SP, Cutter G, Blankson M. The relationship between maternal hematocrit and preg- nancy outcome. Obstet Gynecol 1991;77:190-4.
  • Little MP, Brocard P, Elliott P, Steer PJ. Hemoglobin con- centration in pregnancy and perinatal mortality: a London- based cohort study. Am J Obstet Gynecol 2005;193:220-6.

İkinci Trimester Maternal Hemoglobin Seviyesinin Doğum Ağırlığı ve Haftasına Etkisi

Year 2010, Volume: 2010 Issue: 3, 156 - 160, 01.03.2010
https://doi.org/10.5174/tutfd.2008.00910.3

Abstract

Amaç: Bu çalışmanın amacı ikinci trimester anemisinin
doğum ağırlığı ve doğum haftasına etkisini
araştırmaktır.
Hastalar ve Yöntemler: Ocak 2005 ve Ekim
2007 tarihleri arasında kliniğimizde takip edilen ve
doğum yapan 1116 hastanın kayıtları retrospektif
olarak incelendi. Hastalar ikinci trimester hemoglobin
değerleri

References

  • Hallberg L. Perspectives on nutritional iron deficiency. Annu Rev Nutr 2001;21:1-21.
  • Müngen E. Iron supplementation in pregnancy. J Perinat Med 2003;31:420-6.
  • Hallberg L. Results of surveys to assess iron status in Europe. Nutr Rev 1995;53:314-22.
  • Looker AC, Dallman PR, Carroll MD, Gunter EW, Johnson CL. Prevalence of iron deficiency in the United States. JAMA 1997;277:973-6.
  • DeMaeyer EM. Preventing and controlling iron deficiency anaemia through primary health care. Geneva: World Health Organization; 1989.
  • Di Renzo GC, Roura LC, European Association of Perinatal Medicine-Study Group on Preterm Birth. Guidelines for the management of spontaneous preterm labor. J Perinat Med 2006;34:359-66.
  • Ott WJ. Reevaluation of the relationship between amniotic fluid volume and perinatal outcome. Am J Obstet Gynecol 2005;192:1803-9.
  • Lee JI, Kang SA, Kim SK, Lim HS. A cross sectional study of maternal iron status of Korean women during pregnancy. Nutr Res 2002;22:1377-88.
  • Steer PJ. Maternal hemoglobin concentration and birth weight. Am J Clin Nutr 2000;71(5 Suppl):1285S-7S.
  • Levy A, Fraser D, Katz M, Mazor M, Sheiner E. Maternal anemia during pregnancy is an independent risk factor for low birthweight and preterm delivery. Eur J Obstet Gynecol Reprod Biol 2005;122:182-6.
  • Klebanoff MA, Shiono PH, Selby JV, Trachtenberg AI, Graubard BI. Anemia and spontaneous preterm birth. Am J Obstet Gynecol 1991;164:59-63.
  • Scholl TO, Hediger ML, Fischer RL, Shearer JW. Anemia vs iron deficiency: increased risk of preterm delivery in a prospective study. Am J Clin Nutr 1992;55:985-8.
  • Lee HS, Kim MS, Kim MH, Kim YJ, Kim WY. Iron status and its association with pregnancy outcome in Korean pregnant women. Eur J Clin Nutr 2006;60:1130-5.
  • Milman N, Agger AO, Nielsen OJ. Iron status markers and serum erythropoietin in 120 mothers and newborn infants. Effect of iron supplementation in normal pregnancy. Acta Obstet Gynecol Scand 1994;73:200-4.
  • Krafft A, Breymann C, Streich J, Huch R, Huch A. Hemoglobin concentration in multiple versus singleton pregnancies--retrospective evidence for physiology not pathology. Eur J Obstet Gynecol Reprod Biol 2001;99:184-7.
  • Graves BW, Barger MK. A "conservative" approach to iron supplementation during pregnancy. J Midwifery Womens Health 2001;46:159-66.
  • Keverenge-Ettyang GA, van Marken Lichtenbelt W, Esamai F, Saris W. Maternal nutritional status in pastoral versus farming communities of West Pokot, Kenya: differences in iron and vitamin A status and body composition. Food Nutr Bull 2006;27:228-35.
  • Shobeiri F, Begum K, Nazari M. A prospective study of maternal hemoglobin status of Indian women dur- ing pregnancy and pregnancy outcome. Nutr Res 2006;26:209-13.
  • Lu ZM, Goldenberg RL, Cliver SP, Cutter G, Blankson M. The relationship between maternal hematocrit and preg- nancy outcome. Obstet Gynecol 1991;77:190-4.
  • Little MP, Brocard P, Elliott P, Steer PJ. Hemoglobin con- centration in pregnancy and perinatal mortality: a London- based cohort study. Am J Obstet Gynecol 2005;193:220-6.
There are 20 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Özgür Dündar This is me

Tolga Çiftpınar This is me

Levent Tütüncü This is me

Ali Rüştü Ergür This is me

Mehmet Vedat Atay This is me

Ercüment Müngen This is me

Yusuf Ziya Yergök This is me

Publication Date March 1, 2010
Published in Issue Year 2010 Volume: 2010 Issue: 3

Cite

APA Dündar, Ö., Çiftpınar, T., Tütüncü, L., Ergür, A. R., et al. (2010). İkinci Trimester Maternal Hemoglobin Seviyesinin Doğum Ağırlığı ve Haftasına Etkisi. Balkan Medical Journal, 2010(3), 156-160. https://doi.org/10.5174/tutfd.2008.00910.3
AMA Dündar Ö, Çiftpınar T, Tütüncü L, Ergür AR, Atay MV, Müngen E, Yergök YZ. İkinci Trimester Maternal Hemoglobin Seviyesinin Doğum Ağırlığı ve Haftasına Etkisi. Balkan Medical Journal. March 2010;2010(3):156-160. doi:10.5174/tutfd.2008.00910.3
Chicago Dündar, Özgür, Tolga Çiftpınar, Levent Tütüncü, Ali Rüştü Ergür, Mehmet Vedat Atay, Ercüment Müngen, and Yusuf Ziya Yergök. “İkinci Trimester Maternal Hemoglobin Seviyesinin Doğum Ağırlığı Ve Haftasına Etkisi”. Balkan Medical Journal 2010, no. 3 (March 2010): 156-60. https://doi.org/10.5174/tutfd.2008.00910.3.
EndNote Dündar Ö, Çiftpınar T, Tütüncü L, Ergür AR, Atay MV, Müngen E, Yergök YZ (March 1, 2010) İkinci Trimester Maternal Hemoglobin Seviyesinin Doğum Ağırlığı ve Haftasına Etkisi. Balkan Medical Journal 2010 3 156–160.
IEEE Ö. Dündar, T. Çiftpınar, L. Tütüncü, A. R. Ergür, M. V. Atay, E. Müngen, and Y. Z. Yergök, “İkinci Trimester Maternal Hemoglobin Seviyesinin Doğum Ağırlığı ve Haftasına Etkisi”, Balkan Medical Journal, vol. 2010, no. 3, pp. 156–160, 2010, doi: 10.5174/tutfd.2008.00910.3.
ISNAD Dündar, Özgür et al. “İkinci Trimester Maternal Hemoglobin Seviyesinin Doğum Ağırlığı Ve Haftasına Etkisi”. Balkan Medical Journal 2010/3 (March 2010), 156-160. https://doi.org/10.5174/tutfd.2008.00910.3.
JAMA Dündar Ö, Çiftpınar T, Tütüncü L, Ergür AR, Atay MV, Müngen E, Yergök YZ. İkinci Trimester Maternal Hemoglobin Seviyesinin Doğum Ağırlığı ve Haftasına Etkisi. Balkan Medical Journal. 2010;2010:156–160.
MLA Dündar, Özgür et al. “İkinci Trimester Maternal Hemoglobin Seviyesinin Doğum Ağırlığı Ve Haftasına Etkisi”. Balkan Medical Journal, vol. 2010, no. 3, 2010, pp. 156-60, doi:10.5174/tutfd.2008.00910.3.
Vancouver Dündar Ö, Çiftpınar T, Tütüncü L, Ergür AR, Atay MV, Müngen E, Yergök YZ. İkinci Trimester Maternal Hemoglobin Seviyesinin Doğum Ağırlığı ve Haftasına Etkisi. Balkan Medical Journal. 2010;2010(3):156-60.