VENTRAL HERNİ ONARIMINDA POLİPROPİLEN VE SİLİKON KAPLI POLİPROPİLEN YAMANIN RAT MODELİNDE KARŞILAŞTIRILMASI Comparison of Polypropylene and Silicone-Coated Polypropylene Mesh in Repair of Ventral Hernia in a Rat Model

Yılmaz Ünal; Arif Hakan Demirel; Berkay Küçük; Salih Tuncal; Muzaffer Çaydere

doi:10.16919/bozoktip.444360

VENTRAL HERNİ ONARIMINDA POLİPROPİLEN VE SİLİKON KAPLI POLİPROPİLEN YAMANIN RAT MODELİNDE KARŞILAŞTIRILMASI Comparison of Polypropylene and Silicone-Coated Polypropylene Mesh in Repair of Ventral Hernia in a Rat Model

Abstract

ÖZET

Amaç: Bu çalışma ventral herni tamirinde polipropilen bir yama ile silikon tabaka ve silikon kaplı

polipropilen yamanın etkinliğini karşılaştırmayı amaçlamaktadır.

Gereç ve Yöntem: Toplam 45 Wistar Albino rat 3 eşit gruba ayrıldı(polipropilen yama grubu, silikon

tabaka grubu ve silikon kaplı polipropilen yama grubu). Tüm ratlara 3 cm’lik orta hat insizyonu yapılarak

abdominal defekt oluşturuldu. Defektler polipropilen yama, silikon tabaka ve silikon kaplı

polipropilen yama ile onarıldı. Yamalar doğrudan intraabdominal organlar üzerine yerleştirildi.

Tüm ratlar postoperatif 28.günde sakrifiye edildi. İntraabdominal yapışıklıklar değerlendirildi ve

dokuların kopma kuvvetleri ölçüldü. Histopatolojik değerlendirme için doku örnekleri alındı.

Bulgular: Silikon kaplı polipropilen yama grubunda ortalama adezyon skoru, polipropilen yama

ve silikon tabaka grubundaki ortalama adezyon skorundan anlamlı olarak daha düşük bulundu.

Silikon tabaka grubunda yaranın histopatolojik maturasyon derecesi diğer iki gruptan anlamlı olarak

daha düşüktü. Yama materyallerinin kopma kuvvetleri karşılaştırıldığında; polipropilen yama

grubundaki kopma kuvvetleri diğer iki gruptaki kopma kuvvetlerinden anlamlı olarak daha yüksek

tespit edildi.

Sonuç: Ventral herni tamirinde silikon kaplı bir polipropilen yamanın kullanımı yama ve bağırsaklar

arasında yapışıklığa sebep olmadı ve yama ile omental yapılar arasındaki yapışıklıkları da azalttı.

Anahtar Sözcükler: Cerrahi yama; Ventral herni; Polipropilen; Silikon; Yapışıklıklar

ABSTRACT

Objective: The aim of this study was to compare the efficacy of a silicone sheet(SS) and siliconecoated

polypropylene mesh( SCPM) with a polypropylene mesh(PM) in ventral hernia repair.

Materials and methods: A total of 45 Wistar Albino rats were randomly separated into 3 groups of

15(PM group, SS group and SCPM group). An abdominal defect was created in all the rats using a 3

cm midline incision. The defects were repaired with SS, PM or SCPM meshes which were placed

directly over the abdominal organs. All the rats were sacrificed on postoperative day 28. The intraabdominal

adhesions were evaluated and the breaking strength of the tissues was measured.

Tissue samples were taken from the mesh-fascia junction for the histopathological evaluation.

Results: The mean adhesion score of the SCPM group was found to be significantly lower than

that of the SS and the PM groups. The histopathological wound maturation degree in the SS group

was significantly lower than that of the other two groups. Comparison of the breaking strength

of the mesh materials determined significantly higher breaking strength values in the PM group

compared with the other two groups.

Conclusion: In the repair of ventral hernia, the use of a SCPM did not cause adhesions between

the mesh and the intestines and reduced adhesions between the mesh and omental structures.

Keywords: Surgical mesh; Ventral hernia; Polypropylene; Silicone; Adhesions

Keywords

VENTRAL HERNİ ONARIMINDA POLİPROPİLEN VE SİLİKON KAPLI POLİPROPİLEN YAMANIN RAT MODELİNDE KARŞILAŞTIRILMASI Comparison of Polypropylene and Silicone-Coated Polypropylene Mesh in Repair of Ventral Hernia in a Rat Model

References

1. De Guzman LJ, Nyhus LM, Yared G, Schlesinger PK. Colocutananeous fistula formation following polypropylene mesh placement for repair of a ventral hernia: diagnosis by colonoscopy. Endoscopy 1995; 27: 459-61. 2. Aziz F, Zaeem M. Chronic abdominal pain secondery to mesh erosion into ceacum following incisional hernia repair a case report and lterature review. J Clin Med Res. 2014; 6: 153-5. 3. Norton C, Culver A, Mostafa G. Intraluminal mesh migration after ventral hernia repair. J Gastrointest Surg. 2016; 20: 1920-2. 4. Amid PK, Shulman AG, Liechtenstein IL, Sostrin S, Yong J, Hakakha M. Experimental evaluation of a new composite mesh with the selective property of incorporation to the abdominal wall without adhering to the intestines. J Biomed Mater Res. 1994; 28: 373-5. 5. Baracs J, Takacs I, Shahram GS. Biological behavior of polypropylene meshes suitable for intra-abdominal implantation in animal model. Magy Seb. 2003; 56: 171-6. 6. Takacs I, Horvath S, Balatonyi B, Javor S, Molnar A, Gaspar S et al. Tissue integration of various silicone coated polypropylene surgical mesh. Magy Seb. 2010; 63: 340-6. 7. Becker JM, Dayton MT, Fazio VW, Beck DE, Stryker SJ, Wexner SD et al. Prevention of postoperative abdominal adhesions by a sodium hyaluronate-based bioresorbable membrane: a prospective, randomized, double-blind multicenter study. J Am Coll Surg. 1996; 183: 297-306. 8. De Bord JR. The historical development of prosthetics in hernia surgery. Surg Clin North Am. 1998; 78: 973-1006. 9. Read RC. Milestones in the history of hernia surgery: prosthetic repair. Hernia. 2004; 8: 8-14. 10. Burger JW, Luijendijik RW, Hop WC, Halm JA, Verdaasdonk EG, Jeekel J. Long-term follow up of a randomized controlled trial of suture versus repair of incisional hernia. Ann Surg. 2004; 240: 578-85.

Details

Primary Language

Turkish

Subjects

-

Journal Section

Research Article

Authors

Yılmaz Ünal This is me

Arif Hakan Demirel This is me

Berkay Küçük This is me

Salih Tuncal This is me

Muzaffer Çaydere This is me

Publication Date

March 26, 2019

Submission Date

March 1, 2019

Acceptance Date

-

Published in Issue

Year 2019 Volume: 9 Number: 1

DOI

https://doi.org/10.16919/bozoktip.444360

IZ

https://izlik.org/JA76JP84ED

Cite

RIS / Bibtex

APA

Ünal, Y., Demirel, A. H., Küçük, B., Tuncal, S., & Çaydere, M. (2019). VENTRAL HERNİ ONARIMINDA POLİPROPİLEN VE SİLİKON KAPLI POLİPROPİLEN YAMANIN RAT MODELİNDE KARŞILAŞTIRILMASI Comparison of Polypropylene and Silicone-Coated Polypropylene Mesh in Repair of Ventral Hernia in a Rat Model. Bozok Tıp Dergisi, 9(1), 35-41. https://doi.org/10.16919/bozoktip.444360

AMA

1.Ünal Y, Demirel AH, Küçük B, Tuncal S, Çaydere M. VENTRAL HERNİ ONARIMINDA POLİPROPİLEN VE SİLİKON KAPLI POLİPROPİLEN YAMANIN RAT MODELİNDE KARŞILAŞTIRILMASI Comparison of Polypropylene and Silicone-Coated Polypropylene Mesh in Repair of Ventral Hernia in a Rat Model. Bozok Tıp Dergisi. 2019;9(1):35-41. doi:10.16919/bozoktip.444360

Chicago

Ünal, Yılmaz, Arif Hakan Demirel, Berkay Küçük, Salih Tuncal, and Muzaffer Çaydere. 2019. “VENTRAL HERNİ ONARIMINDA POLİPROPİLEN VE SİLİKON KAPLI POLİPROPİLEN YAMANIN RAT MODELİNDE KARŞILAŞTIRILMASI Comparison of Polypropylene and Silicone-Coated Polypropylene Mesh in Repair of Ventral Hernia in a Rat Model”. Bozok Tıp Dergisi 9 (1): 35-41. https://doi.org/10.16919/bozoktip.444360.

EndNote

Ünal Y, Demirel AH, Küçük B, Tuncal S, Çaydere M (March 1, 2019) VENTRAL HERNİ ONARIMINDA POLİPROPİLEN VE SİLİKON KAPLI POLİPROPİLEN YAMANIN RAT MODELİNDE KARŞILAŞTIRILMASI Comparison of Polypropylene and Silicone-Coated Polypropylene Mesh in Repair of Ventral Hernia in a Rat Model. Bozok Tıp Dergisi 9 1 35–41.

IEEE

[1]Y. Ünal, A. H. Demirel, B. Küçük, S. Tuncal, and M. Çaydere, “VENTRAL HERNİ ONARIMINDA POLİPROPİLEN VE SİLİKON KAPLI POLİPROPİLEN YAMANIN RAT MODELİNDE KARŞILAŞTIRILMASI Comparison of Polypropylene and Silicone-Coated Polypropylene Mesh in Repair of Ventral Hernia in a Rat Model”, Bozok Tıp Dergisi, vol. 9, no. 1, pp. 35–41, Mar. 2019, doi: 10.16919/bozoktip.444360.

ISNAD

Ünal, Yılmaz - Demirel, Arif Hakan - Küçük, Berkay - Tuncal, Salih - Çaydere, Muzaffer. “VENTRAL HERNİ ONARIMINDA POLİPROPİLEN VE SİLİKON KAPLI POLİPROPİLEN YAMANIN RAT MODELİNDE KARŞILAŞTIRILMASI Comparison of Polypropylene and Silicone-Coated Polypropylene Mesh in Repair of Ventral Hernia in a Rat Model”. Bozok Tıp Dergisi 9/1 (March 1, 2019): 35-41. https://doi.org/10.16919/bozoktip.444360.

JAMA

1.Ünal Y, Demirel AH, Küçük B, Tuncal S, Çaydere M. VENTRAL HERNİ ONARIMINDA POLİPROPİLEN VE SİLİKON KAPLI POLİPROPİLEN YAMANIN RAT MODELİNDE KARŞILAŞTIRILMASI Comparison of Polypropylene and Silicone-Coated Polypropylene Mesh in Repair of Ventral Hernia in a Rat Model. Bozok Tıp Dergisi. 2019;9:35–41.

MLA

Ünal, Yılmaz, et al. “VENTRAL HERNİ ONARIMINDA POLİPROPİLEN VE SİLİKON KAPLI POLİPROPİLEN YAMANIN RAT MODELİNDE KARŞILAŞTIRILMASI Comparison of Polypropylene and Silicone-Coated Polypropylene Mesh in Repair of Ventral Hernia in a Rat Model”. Bozok Tıp Dergisi, vol. 9, no. 1, Mar. 2019, pp. 35-41, doi:10.16919/bozoktip.444360.

Vancouver

1.Yılmaz Ünal, Arif Hakan Demirel, Berkay Küçük, Salih Tuncal, Muzaffer Çaydere. VENTRAL HERNİ ONARIMINDA POLİPROPİLEN VE SİLİKON KAPLI POLİPROPİLEN YAMANIN RAT MODELİNDE KARŞILAŞTIRILMASI Comparison of Polypropylene and Silicone-Coated Polypropylene Mesh in Repair of Ventral Hernia in a Rat Model. Bozok Tıp Dergisi. 2019 Mar. 1;9(1):35-41. doi:10.16919/bozoktip.444360