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HEMOPTİZİ: TANISAL YÖNTEMLERİN KARŞILAŞTIRILMASI VE AKCİĞER KANSERİ İÇİN RİSK FAKTÖRLERİNİN BELİRLENMESİ Hemoptysis: Comparison of Diagnostic Modalities, and Prediction of Risk Factors of Lung Cancer

Year 2016, Volume: 6 Issue: 2, 38 - 47, 19.12.2016

Abstract

Amaç: Hemoptizinin farklı etyolojik nedenlerinin sıklığını, bilgisayarlı akciğer tomografisi, bronkoskopinin

tanısal başarısını ve cut-off değerleriyle akciğer kanseri için risk faktörlerini belirlemeye

çalıştık.

Gereç ve Yöntemler: Bozok Üniversitesi ve Yozgat Devlet Hastanesinde mayıs 2009 ve ocak 2012

tarihleri arasında hemoptizisi olan 80 hasta retrospektif incelendi.

Bulgular: Hastalar yaş ortalaması 48.1±10.71 (21-71) yıl olan 47 (58.8%) erkek ve 33(41.2%) kadından

oluşmaktadır. Hemoptizinin ana etyolojisi bronşiektazi (42.5%) takiben akciğer kanseri

(17.5%), pnömoni (15%), akciğer absesi (8.8%) ve idiopatik (16.2%) idi. Akciğer tomografisinin tanısal

başarısı 52.5% ve bronkoskopinin 37.5% iken beraber kullanıldıklarında başarı 83.8% olmaktadır.

Kanser ve kanser-dışı grup arasında yaş (p<0.001), hemoptizi miktarı (p=0.011), hemoptizi

süresi (p<0.001) ve sigara içiciliği paket/yıl (p<0.001) açısından istatistiksel anlamlı fark vardı. Akciğer

kanseri hastalarında hemopizi süresi için 10 gün (Se: 92.86%; Sp: 81.82), kanama miktarı için 40

ml (Se: 92.86%; Sp: 45.45), sigara için 18 paket/yıl (Se: 92.86%; Sp: 96.97%) ve yaş için 56 yıl (Se:

100%; Sp: 100%) cut-off değerleri bulundu.

Sonuç: Hemoptizinin en sık nedenleri olarak bronşiektazi ve akciğer kanserini bulduk. Teşhis için

akciğer tomografisi ve bronkoskopi tamamlayıcı yöntemlerdir. Akciğer kanseri tanısını atlamamak

için tanımlanmış rsik faktörleri akılda tutulmalıdır.



ABSTRACT

Background: We aimed to identify the relative frequency of different etiologies of hemoptysis,

diagnostic yield of computerized chest tomography, bronchoscopy and risk factors for lung cancer

with their cut-off levels.

Method: We reviewed 80 patients with hemoptysis retrospectively at the Yozgat State Hospital

and Bozok University Hospital, Yozgat, Turkey between May 2009 and January 2012.

Results: There were 47 male (58.8%) and 33 female (41.2%) patients with a mean age of 48.1±10.71

(21-71) years. The main etiology of hemoptysis was bronchiectasis (42.5%), followed by lung

cancer (17.5%), pneumonia (15%), lung abscess (8.8%) and idiopathic (16.2%). The diagnostic yield

of chest CT was 52.5% and that of bronchoscopy was 37.5% while the yield was 83.8% together.

There was statistically significant difference between cancer and non-cancer group patients in

terms of age (p<0.001), volume of hemoptysis (p=0.011), duration of hemoptysis (p<0.001), and

smoking duration package/years (p<0.001). The cut-off value in the lung cancer patients was

found for the duration of hemoptysis as 10 days (Se: 92.86%; Sp: 81.82), the amount of bleeding

as 40 ml (Se: 92.86%; Sp: 45.45), package/years for smoking as 18 (Se: 92.86%; Sp: 96.97%), and

the age as 56 years (Se: 100%; Sp: 100%).

Conclusion: We found that bronchiectasis and lung cancer were the most common reasons for

hemoptysis. CT of the chest and bronchoscopy are complementary modalities for the diagnosis.

Defined risk factors should be kept in mind not to skip the diagnosis of lung cancer.

References

  • 1. Dorland’s Illustrated Medical Dictionary. 28th ed. Philadelphia: W.B. Saunders Company, 1994. pg. 750.
  • 2. Ozlu T. Massif Hemoptizi. In: Ekim N, Türktaş H (edit). Göğüs Hastalıkları Acilleri. 1st ed., Ankara, Bilimsel Tıp Yayınevi, 2000. p. 241-6.
  • 3. Fishman AP. Approach to the patient with respiratory symptoms. In: Fishman AP (edit). Fishman’s pulmonary diseases and disorders. 4th ed., New York, McGraw-Hill, 2008. p. 387-425.
  • 4. Hirshberg B, Biran I, Glazer M, Kramer MR. Haemoptysis Aetiology, evaluation and outcome in a tertiary referal hospital. Chest. 1997;112(2):440-4.
  • 5. Fidan A, Ozdogan S, Oruç O, et al. Hemoptysis: A retrospective analysis 108 cases. Respir Med. 2002;96(9):677-80.
  • 6. Santiago S, Tobias J, Wiiliams AJ. A reappraisal of the causes of haemoptysis. Arch Intern Med. 1991;151(12):2449-2451.
  • 7. McGuinness G, Beacher JR, Harkin TJ. Hemoptysis: Prospective high-resolution CT/ bronchoscopic correlation. Chest. 1994;105(4):1155-62.
  • 8. Tsoumakidou M, Chrysofakis G, Tsiligianni I, et al. A prospective analysis of 184 hemoptysis cases: diagnostic impact of chest X-ray, computed tomography, bronchoscopy. Respiration. 2006;73(6):808-14.
  • 9. Prasad R, Garg R, Singhal S, Srivastava P. Lessons from patients with hemoptysis attending a chest clinic in India. Ann Thorac Med. 2009;4(1):10-2.
  • 10. Abal AT, Nair PC and Cherian J. Haemoptysis: Aetiology, evaluation and outcome a prospective study in a third world country. Respir Med. 2001;95(7):548-52.
Year 2016, Volume: 6 Issue: 2, 38 - 47, 19.12.2016

Abstract

References

  • 1. Dorland’s Illustrated Medical Dictionary. 28th ed. Philadelphia: W.B. Saunders Company, 1994. pg. 750.
  • 2. Ozlu T. Massif Hemoptizi. In: Ekim N, Türktaş H (edit). Göğüs Hastalıkları Acilleri. 1st ed., Ankara, Bilimsel Tıp Yayınevi, 2000. p. 241-6.
  • 3. Fishman AP. Approach to the patient with respiratory symptoms. In: Fishman AP (edit). Fishman’s pulmonary diseases and disorders. 4th ed., New York, McGraw-Hill, 2008. p. 387-425.
  • 4. Hirshberg B, Biran I, Glazer M, Kramer MR. Haemoptysis Aetiology, evaluation and outcome in a tertiary referal hospital. Chest. 1997;112(2):440-4.
  • 5. Fidan A, Ozdogan S, Oruç O, et al. Hemoptysis: A retrospective analysis 108 cases. Respir Med. 2002;96(9):677-80.
  • 6. Santiago S, Tobias J, Wiiliams AJ. A reappraisal of the causes of haemoptysis. Arch Intern Med. 1991;151(12):2449-2451.
  • 7. McGuinness G, Beacher JR, Harkin TJ. Hemoptysis: Prospective high-resolution CT/ bronchoscopic correlation. Chest. 1994;105(4):1155-62.
  • 8. Tsoumakidou M, Chrysofakis G, Tsiligianni I, et al. A prospective analysis of 184 hemoptysis cases: diagnostic impact of chest X-ray, computed tomography, bronchoscopy. Respiration. 2006;73(6):808-14.
  • 9. Prasad R, Garg R, Singhal S, Srivastava P. Lessons from patients with hemoptysis attending a chest clinic in India. Ann Thorac Med. 2009;4(1):10-2.
  • 10. Abal AT, Nair PC and Cherian J. Haemoptysis: Aetiology, evaluation and outcome a prospective study in a third world country. Respir Med. 2001;95(7):548-52.
There are 10 citations in total.

Details

Subjects Health Care Administration
Journal Section Review
Authors

Yavuz Selim İntepe This is me

Yener Aydın This is me

Publication Date December 19, 2016
Published in Issue Year 2016 Volume: 6 Issue: 2

Cite

APA İntepe, Y. S., & Aydın, Y. (2016). HEMOPTİZİ: TANISAL YÖNTEMLERİN KARŞILAŞTIRILMASI VE AKCİĞER KANSERİ İÇİN RİSK FAKTÖRLERİNİN BELİRLENMESİ Hemoptysis: Comparison of Diagnostic Modalities, and Prediction of Risk Factors of Lung Cancer. Bozok Tıp Dergisi, 6(2), 38-47.
AMA İntepe YS, Aydın Y. HEMOPTİZİ: TANISAL YÖNTEMLERİN KARŞILAŞTIRILMASI VE AKCİĞER KANSERİ İÇİN RİSK FAKTÖRLERİNİN BELİRLENMESİ Hemoptysis: Comparison of Diagnostic Modalities, and Prediction of Risk Factors of Lung Cancer. Bozok Tıp Dergisi. December 2016;6(2):38-47.
Chicago İntepe, Yavuz Selim, and Yener Aydın. “HEMOPTİZİ: TANISAL YÖNTEMLERİN KARŞILAŞTIRILMASI VE AKCİĞER KANSERİ İÇİN RİSK FAKTÖRLERİNİN BELİRLENMESİ Hemoptysis: Comparison of Diagnostic Modalities, and Prediction of Risk Factors of Lung Cancer”. Bozok Tıp Dergisi 6, no. 2 (December 2016): 38-47.
EndNote İntepe YS, Aydın Y (December 1, 2016) HEMOPTİZİ: TANISAL YÖNTEMLERİN KARŞILAŞTIRILMASI VE AKCİĞER KANSERİ İÇİN RİSK FAKTÖRLERİNİN BELİRLENMESİ Hemoptysis: Comparison of Diagnostic Modalities, and Prediction of Risk Factors of Lung Cancer. Bozok Tıp Dergisi 6 2 38–47.
IEEE Y. S. İntepe and Y. Aydın, “HEMOPTİZİ: TANISAL YÖNTEMLERİN KARŞILAŞTIRILMASI VE AKCİĞER KANSERİ İÇİN RİSK FAKTÖRLERİNİN BELİRLENMESİ Hemoptysis: Comparison of Diagnostic Modalities, and Prediction of Risk Factors of Lung Cancer”, Bozok Tıp Dergisi, vol. 6, no. 2, pp. 38–47, 2016.
ISNAD İntepe, Yavuz Selim - Aydın, Yener. “HEMOPTİZİ: TANISAL YÖNTEMLERİN KARŞILAŞTIRILMASI VE AKCİĞER KANSERİ İÇİN RİSK FAKTÖRLERİNİN BELİRLENMESİ Hemoptysis: Comparison of Diagnostic Modalities, and Prediction of Risk Factors of Lung Cancer”. Bozok Tıp Dergisi 6/2 (December 2016), 38-47.
JAMA İntepe YS, Aydın Y. HEMOPTİZİ: TANISAL YÖNTEMLERİN KARŞILAŞTIRILMASI VE AKCİĞER KANSERİ İÇİN RİSK FAKTÖRLERİNİN BELİRLENMESİ Hemoptysis: Comparison of Diagnostic Modalities, and Prediction of Risk Factors of Lung Cancer. Bozok Tıp Dergisi. 2016;6:38–47.
MLA İntepe, Yavuz Selim and Yener Aydın. “HEMOPTİZİ: TANISAL YÖNTEMLERİN KARŞILAŞTIRILMASI VE AKCİĞER KANSERİ İÇİN RİSK FAKTÖRLERİNİN BELİRLENMESİ Hemoptysis: Comparison of Diagnostic Modalities, and Prediction of Risk Factors of Lung Cancer”. Bozok Tıp Dergisi, vol. 6, no. 2, 2016, pp. 38-47.
Vancouver İntepe YS, Aydın Y. HEMOPTİZİ: TANISAL YÖNTEMLERİN KARŞILAŞTIRILMASI VE AKCİĞER KANSERİ İÇİN RİSK FAKTÖRLERİNİN BELİRLENMESİ Hemoptysis: Comparison of Diagnostic Modalities, and Prediction of Risk Factors of Lung Cancer. Bozok Tıp Dergisi. 2016;6(2):38-47.
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