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MEDİAL MENİSKAL EKSTRÜZYON İLE DEJENERATİF ARTRİTİN NEDEN SONUÇ İLİŞKİSİ BAKIMINDAN İNCELENMESİ Investigation of the Cause-Effect Relationship Between Degenerative Arthritis and Medial Meniscal Extrusion

Year 2020, Volume: 10 Issue: 2, 16 - 22, 08.06.2020

Abstract

ÖZET
Amaç: Diz ekleminde önemli bir biyomekanik etkiye sahip olan menisküsün yapısal bozukluklar ile, erişkin
bireylerde sık rastlanan osteoartrit süreci ile olan ilişkisinin neden-sonuç ilişkisi bakımından irdelemek.
Yöntem: 46 kadın ve 48 erkekten oluşan hastalara ait 94 diz MR tetkiki retrospektif olarak gözden geçirildi.
Bu olgularda medial meniskal yer değişiklikleri-ekstrüzyonlar ve aynı zamanda MR görüntülerde tibiofemoral
kartilaj kalınlıkları, eklem mesafeleri ve medial menisküsü destekleyen temel ligamanlardan olan MCL’nin
durumu ya da hasar dereceleri değerlendirildi ve bulgular karşılaştırıldı.
Bulgular: Yaş ortalaması 47,9±12,7 olan 46 kadın ve 48 erkek hastaya ait toplamda 94 diz MR değerlendirildi.
Olguların yaş ortalamaları arttıkça medial eklem aralığı ve medial menisküs ekstrüzyon (MME) derecesi arasında
anlamlı korelasyon saptandı. Medial eklem mesafesi ile medial ve lateral kartilaj kalınlıkları arasında
ve lateral eklem aralığı arasında pozitif korelasyon saptandı. Medial menisküs hasar derecesi arttıkça medial
kartilaj kalınlıkları azalırken MME derecesi artmakta idi. Ayrıca lateral kartilaj kalınlıkları ile lateral meniskal
ekstrüzyon (LME) derecesi arasında negatif korelasyon saptandı. MCL hasar derecelerine göre gruplar arasında
medial ekstrüzyon (MME) açısından istatistiksel olarak anlamlı fark saptandı (p<0,001).
Sonuç: Meniskal ekstrüzyon yaş ile artan dejeneratif süreçlerin de birlikteliğinde oldukça sık görülmektedir.
Meniskal ekstrüzyon oranı, MCL gibi komşu ligaman hasarlarında da artmaktadır. Gerek osteoartrit gerek
meniskopati ve gerekse ligaman hasarları bir arada görülebilmekle birlikte meniskal ekstrüzyon, kartilaj hasarını
kolaylaştırdığından dejeneratif artrit gelişiminin nedenlerinden sayılabilir.
Anahtar sözcükler: Manyetik rezonans görüntüleme; Menisküsler; Medial; Menisküsler; Lateral; Osteoartrit;
Diz; ligamentler.
ABSTRACT
Objective: The aim of this study was to investigate the relationship between the structural disorders of the
meniscus with a significant biomechanical effect in the knee joint with the common osteoarthritis process
in adult subjects.
Methods: Knee MRI images of 94 females and 48 males were retrospectively evaluated in this study. In
these cases, medial meniscal displacements-extrusions, as well as the tibiofemoral cartilage thickness and
injury of the MCL, one of the basic ligaments supporting the knee medially, joint distances and meniscus
injury were investigated, and the findings were compared.
Results: A total of 94 knee MRIs of 46 female and 48 male patients with a mean age of 47.9 ± 12.7 were
evaluated. There was a significant correlation between medial joint space and medial meniscus extrusion
(MME) degree as the mean age of the patients increased. There was a positive correlation between medial
joint distance and medial and lateral cartilage thicknesses and lateral joint space. As the medial meniscus
damage degree increased, the medial cartilage thickness decreased and the MME degree was increased. In
addition, there was a negative correlation between lateral cartilage thickness and lateral meniscal extrusion
(LME) degree. There was a statistically significant difference between the groups with MME and MCL injury
(p <0,001).
Conclusion: Meniscal extrusion is a common finding with degenerative processes that increase with age.
The meniscal extrusion ratio is also increased in adjacent ligament damage such as MCL. Although both OA
and meniscopathy and ligament damage can be seen together, meniscal extrusion can be considered as a
cause of degenerative arthritis because it facilitates cartilage damage.
Keywords: Magnetic Resonance Imaging; Meniscus; osteoarthritis; Knee joint; Ligaments; MME

References

  • 1. Conaghan PG, Hunter DJ, Maillefert JF, Reichmann WM, Losina E. Summary and recommendations of the OARSI FDA osteoarthritis assessment of structural change working group. Osteoarthritis Cartilage. 2011;19:606–10. 2. Patel R, Eltgroth M, Souza R, Zhang CA, Majumdar S, Link TM, etal. Loaded versus unloaded magnetic resonance imaging (MRI) of the knee: Effect on meniscus extrusion in healthy volunteers and patients with osteoarthritis. Eur J Radiol Open. 2016;20;3:100-7. 3. Hall J, Laslett LL, Martel-Pelletier J, Pelletier JP, Abram F, Ding CH. Change in knee structure and change intibiofemoral joint space width: a five-year longitudinal population–based study. BMC Musculoskelet Disord. 2016;14:17-25. 4. Arno S, Bell CP, Xia D, Regatte RR, Krasnokutsky S, Samuels J. Relationship between meniscal integrity and risk factors for cartilage degeneration. Knee. 2016;23(4):686-91 5. Kenny C. Radial displacement of the medial meniscus and Fairbank’s signs. Clinical Orthopaedics and Related Research. 1997; 339:163–173. 6. Ohi G, Kimura M, Asagumo H, Kanbayashi S, Kobayashi A,Taki M. The relation between radial displacement of medial meniscus and grade of chondral lesion in early osteoarthritis of the knee. East Japan Journal of Orthopaedic and Traumatology. 2006; Vol. 18: 155–159. 7. Kijima H, Miyakoshi N, Kasukawa Y, Ishikawa Y, Kinoshita H, Ohuchi K et al. Cut-Off Value of Medial Meniscal Extrusion for Knee Pain. Adv Orthop. 2017;2017:6793026. 8. Hada S, Ishijima M, Kaneko H, Kinoshita M, Liu L, Sadatsuki R et al. Association of medial meniscal extrusion with medial tibial osteophyte distance detected by T2 mapping MRI in patients with early-stage knee osteoarthritis. Arthritis Res Ther. 2017; 12;19(1):201. 9.Teichtahl AJ, Cicuttini FM, Abram F, Wang Y, Pelletier JP, Dodin P et al. Meniscal extrusion and bone marrow lesions are associated with incident and progressive knee osteoarthritis. Osteoarthritis Cartilage. 2017;25(7):1076-1083. 10. Roubille C, Martel-Pelletier J, Raynauld JP, Abram F, Dorais M, Delorme P, et al. Meniscal extrusion promotes knee osteoarthritis structural progression: protective effect of strontium ranelate treatment in a phase III clinical trial. Arthritis Res Ther 2015 Mar 23;17(1):82.
Year 2020, Volume: 10 Issue: 2, 16 - 22, 08.06.2020

Abstract

References

  • 1. Conaghan PG, Hunter DJ, Maillefert JF, Reichmann WM, Losina E. Summary and recommendations of the OARSI FDA osteoarthritis assessment of structural change working group. Osteoarthritis Cartilage. 2011;19:606–10. 2. Patel R, Eltgroth M, Souza R, Zhang CA, Majumdar S, Link TM, etal. Loaded versus unloaded magnetic resonance imaging (MRI) of the knee: Effect on meniscus extrusion in healthy volunteers and patients with osteoarthritis. Eur J Radiol Open. 2016;20;3:100-7. 3. Hall J, Laslett LL, Martel-Pelletier J, Pelletier JP, Abram F, Ding CH. Change in knee structure and change intibiofemoral joint space width: a five-year longitudinal population–based study. BMC Musculoskelet Disord. 2016;14:17-25. 4. Arno S, Bell CP, Xia D, Regatte RR, Krasnokutsky S, Samuels J. Relationship between meniscal integrity and risk factors for cartilage degeneration. Knee. 2016;23(4):686-91 5. Kenny C. Radial displacement of the medial meniscus and Fairbank’s signs. Clinical Orthopaedics and Related Research. 1997; 339:163–173. 6. Ohi G, Kimura M, Asagumo H, Kanbayashi S, Kobayashi A,Taki M. The relation between radial displacement of medial meniscus and grade of chondral lesion in early osteoarthritis of the knee. East Japan Journal of Orthopaedic and Traumatology. 2006; Vol. 18: 155–159. 7. Kijima H, Miyakoshi N, Kasukawa Y, Ishikawa Y, Kinoshita H, Ohuchi K et al. Cut-Off Value of Medial Meniscal Extrusion for Knee Pain. Adv Orthop. 2017;2017:6793026. 8. Hada S, Ishijima M, Kaneko H, Kinoshita M, Liu L, Sadatsuki R et al. Association of medial meniscal extrusion with medial tibial osteophyte distance detected by T2 mapping MRI in patients with early-stage knee osteoarthritis. Arthritis Res Ther. 2017; 12;19(1):201. 9.Teichtahl AJ, Cicuttini FM, Abram F, Wang Y, Pelletier JP, Dodin P et al. Meniscal extrusion and bone marrow lesions are associated with incident and progressive knee osteoarthritis. Osteoarthritis Cartilage. 2017;25(7):1076-1083. 10. Roubille C, Martel-Pelletier J, Raynauld JP, Abram F, Dorais M, Delorme P, et al. Meniscal extrusion promotes knee osteoarthritis structural progression: protective effect of strontium ranelate treatment in a phase III clinical trial. Arthritis Res Ther 2015 Mar 23;17(1):82.
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Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Original Research
Authors

Nilüfer Aylanç This is me

Şenay Bengin Ertem This is me

Publication Date June 8, 2020
Published in Issue Year 2020 Volume: 10 Issue: 2

Cite

APA Aylanç, N., & Ertem, Ş. B. (2020). MEDİAL MENİSKAL EKSTRÜZYON İLE DEJENERATİF ARTRİTİN NEDEN SONUÇ İLİŞKİSİ BAKIMINDAN İNCELENMESİ Investigation of the Cause-Effect Relationship Between Degenerative Arthritis and Medial Meniscal Extrusion. Bozok Tıp Dergisi, 10(2), 16-22.
AMA Aylanç N, Ertem ŞB. MEDİAL MENİSKAL EKSTRÜZYON İLE DEJENERATİF ARTRİTİN NEDEN SONUÇ İLİŞKİSİ BAKIMINDAN İNCELENMESİ Investigation of the Cause-Effect Relationship Between Degenerative Arthritis and Medial Meniscal Extrusion. Bozok Tıp Dergisi. June 2020;10(2):16-22.
Chicago Aylanç, Nilüfer, and Şenay Bengin Ertem. “MEDİAL MENİSKAL EKSTRÜZYON İLE DEJENERATİF ARTRİTİN NEDEN SONUÇ İLİŞKİSİ BAKIMINDAN İNCELENMESİ Investigation of the Cause-Effect Relationship Between Degenerative Arthritis and Medial Meniscal Extrusion”. Bozok Tıp Dergisi 10, no. 2 (June 2020): 16-22.
EndNote Aylanç N, Ertem ŞB (June 1, 2020) MEDİAL MENİSKAL EKSTRÜZYON İLE DEJENERATİF ARTRİTİN NEDEN SONUÇ İLİŞKİSİ BAKIMINDAN İNCELENMESİ Investigation of the Cause-Effect Relationship Between Degenerative Arthritis and Medial Meniscal Extrusion. Bozok Tıp Dergisi 10 2 16–22.
IEEE N. Aylanç and Ş. B. Ertem, “MEDİAL MENİSKAL EKSTRÜZYON İLE DEJENERATİF ARTRİTİN NEDEN SONUÇ İLİŞKİSİ BAKIMINDAN İNCELENMESİ Investigation of the Cause-Effect Relationship Between Degenerative Arthritis and Medial Meniscal Extrusion”, Bozok Tıp Dergisi, vol. 10, no. 2, pp. 16–22, 2020.
ISNAD Aylanç, Nilüfer - Ertem, Şenay Bengin. “MEDİAL MENİSKAL EKSTRÜZYON İLE DEJENERATİF ARTRİTİN NEDEN SONUÇ İLİŞKİSİ BAKIMINDAN İNCELENMESİ Investigation of the Cause-Effect Relationship Between Degenerative Arthritis and Medial Meniscal Extrusion”. Bozok Tıp Dergisi 10/2 (June 2020), 16-22.
JAMA Aylanç N, Ertem ŞB. MEDİAL MENİSKAL EKSTRÜZYON İLE DEJENERATİF ARTRİTİN NEDEN SONUÇ İLİŞKİSİ BAKIMINDAN İNCELENMESİ Investigation of the Cause-Effect Relationship Between Degenerative Arthritis and Medial Meniscal Extrusion. Bozok Tıp Dergisi. 2020;10:16–22.
MLA Aylanç, Nilüfer and Şenay Bengin Ertem. “MEDİAL MENİSKAL EKSTRÜZYON İLE DEJENERATİF ARTRİTİN NEDEN SONUÇ İLİŞKİSİ BAKIMINDAN İNCELENMESİ Investigation of the Cause-Effect Relationship Between Degenerative Arthritis and Medial Meniscal Extrusion”. Bozok Tıp Dergisi, vol. 10, no. 2, 2020, pp. 16-22.
Vancouver Aylanç N, Ertem ŞB. MEDİAL MENİSKAL EKSTRÜZYON İLE DEJENERATİF ARTRİTİN NEDEN SONUÇ İLİŞKİSİ BAKIMINDAN İNCELENMESİ Investigation of the Cause-Effect Relationship Between Degenerative Arthritis and Medial Meniscal Extrusion. Bozok Tıp Dergisi. 2020;10(2):16-22.
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