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ENDOMETRİAL ÖRNEKLEME SONUÇLARIMIZ: 365 OLGUNUN ANALİZİ Results of Our Endometrial Samplings: Analysis of 365 Cases

Year 2020, Volume: 10 Issue: 2, 28 - 32, 08.06.2020

Abstract

ÖZET
Amaç: Çalışmamızın amacı çeşitli nedenler ile yapılan endometrial
örnekleme işleminin; endikasyonları ve
histopatolojik tanılarının değerlendirilmesi.
Gereç ve Yöntem: Bu çalışmada Ocak 2015-Mart 2018 tarihleri arasında kliniğimizde
çeşitli nedenler ile endometrial
biyopsi yapılan 365 hastanın endometrial biyopsi sonuçları retrospektif olarak değerlendirildi.
Bulgular: Hastaların yaş ortalaması 46,7±9,9 idi. Endometrial biyopsi endikasyonları sırasıyla anormal uterin
kanama (%74), postmenopozal kanama (%11,5) ve postmenopozal endometrial kalınlık artışı (%14,5) idi. Histopatolojik
sonuçlar ise en sık proliferatif endometrium (%32,1) sonrasında sırasıyla sekretuar endometrium
(%23), endometrial polip (%16,4), yetersiz materyal (%12,9), atrofi (%8,8), basit atipisiz endometrial hiperplazi
(%5,2), endometrial kanser (%1,1) olarak raporlandı. Premenopozal dönemde sekretuar endometrium ve
proliferatif endometrium yüksek oranda bulunurken (p<0.001); postmenopozal dönemde ise atrofi (p<0.001),
yetersiz materyal (p<0.001) ve endometrium kanseri (p=0.004) yüksek oranda bulundu.
Sonuç: Endometrial biyopside esas amaç endometrium kanserini saptamaktır. Özellikle postmenopozal dönemde
endometrium kanseri açısından dikkatli olunmalıdır.
Anahtar kelimeler: Uterus kanaması; Menoraji; Metroraji; Biyopsi; Histopatoloji
ABSTRACT
Aim: Aim of the recent study to evaulate the relation between indications
and histopathological diagnosis of
the endometrial sampling
procedures performed for various indications.
Material and Methods: In this retrospective study endometrial biopsies of 365 patients who had undergone
endometrial biopsy due to various causes between January 2015 and March 2018 at our clinic were evaluated
retrospectively.
Results: The mean age of patients was 46,7±9,9. The indications were abnormal uterine bleeding (%74),
postmenopausal bleeding (%11.5), postmenopausal increased endometrial thickness (%14,5). The most
common histopathological result was proliferative endometrium (%32.1) the others respectively; secretory
endometrium (%23), endometrial polpys (%16.4), insufficient material (%12.9), atrophy (%8.8), simple
endometrial hyperplasia without atypia (%5.2), endometrial cancer (%1.1). In premenapousal group had a
higher incidence of secretory and proliferative endometrium (p<0.001) while in postmenapousal group had a
higher incidence of atrophy, insufficient material and malignancy (p<0.001).
Conclusion: In endometrial biopsy the main aim is to determine endometrial cancer. Particular attention
should be paid to endometrial cancer in postmenopausal period.
Key words: Uterine bleeding; Menorrhagia; Metrorrhagia; Biopsy; Histopathology

References

  • 1. Doraiswami S, Johnson T, Rao S, Rajkumar A, Vijayaraghavan J, Panicker VK. Study of endometrial pathology in abnormal uterine bleeding. J Obstet Gynaecol India 2011;61(4):426-30. 2. Committee on Practice Bulletins—Gynecology. Practice bulletin no. 128: diagnosis of abnormal uterine bleeding in reproductive-aged women. Obstet. Gynecol. Clin. North Am. 2012;120:197-206. 3. Munro MG, Critchley HO, Broder MS, Fraser IS. FIGO classification system (PALM-COEIN) for causes of abnormal uterine bleeding in nongravid women of reproductiveage. FIGO Working Group on Menstrual Disorders. Int J Gynaecol Obstet. 2011;113:3-13. 4. Sarı N, Şahin S, Çağlayan EK, Seçkin L, Kara M, Engin Üstün Y. Endometri̇al Örnekleme Sonuçlarımız: 495 Olgunun Analizi. Düzce Tıp Fakültesi Dergisi 2015; 17(2):70-72. 5. Kucur SK, Şencan H, Yüksel KB, Gözükara İ, Seven A, Keskin N, et al. Endometrial Örnekleme Sonuçlarimiz: 744 Olgunun Analizi (Evaluation Of Endometrial Biopsy Results In Our Clinic; Analysis Of 744 Cases). Zeynep Kamil Tıp Bülteni. 2014;45:146-50. 6. Jetley S, Rana S, Jairajpuri ZS. Morphological spectrum of endometrial pathology in middle-aged women with atypical uterine bleeding: A study of 219 cases. J. Mid-life Health. 2013;4:216-20. 7. Çintesun E, Çintesun FNİ, Aslan BK, Uçar MG, Yarıkkaya E. Endometrial Örnekleme Sonuçlarımız: 655 Olgunun Analizi. Jinekoloji - Obstetrik ve Neonatoloji Tıp Dergisi 2017;14(2):56-9. 8. Aker SŞ, Yüce T, Acar D, Atabekoğlu CS. Anormal Uterin Kanaması olan Kadınlarda Endometrial Örnekleme Sonuçları: 765 Vakanın Retrospektif Analizi. Cukurova Medical Journal. 2015;40:306-10. 9. Williams AR, Brechin S, Porter AJL, Warner P, Critchley HOD. Factors affecting adequacy of pipelle and Tao Brush endometrial sampling. BJOG 2008;115:1028–36. 10. Bakour SH, Khan KS, Gupta JK. Controlled analysis of factors associated with insufficient sample on outpatient endometrial biopsy. BJOG 2000;107:1312–4.
Year 2020, Volume: 10 Issue: 2, 28 - 32, 08.06.2020

Abstract

References

  • 1. Doraiswami S, Johnson T, Rao S, Rajkumar A, Vijayaraghavan J, Panicker VK. Study of endometrial pathology in abnormal uterine bleeding. J Obstet Gynaecol India 2011;61(4):426-30. 2. Committee on Practice Bulletins—Gynecology. Practice bulletin no. 128: diagnosis of abnormal uterine bleeding in reproductive-aged women. Obstet. Gynecol. Clin. North Am. 2012;120:197-206. 3. Munro MG, Critchley HO, Broder MS, Fraser IS. FIGO classification system (PALM-COEIN) for causes of abnormal uterine bleeding in nongravid women of reproductiveage. FIGO Working Group on Menstrual Disorders. Int J Gynaecol Obstet. 2011;113:3-13. 4. Sarı N, Şahin S, Çağlayan EK, Seçkin L, Kara M, Engin Üstün Y. Endometri̇al Örnekleme Sonuçlarımız: 495 Olgunun Analizi. Düzce Tıp Fakültesi Dergisi 2015; 17(2):70-72. 5. Kucur SK, Şencan H, Yüksel KB, Gözükara İ, Seven A, Keskin N, et al. Endometrial Örnekleme Sonuçlarimiz: 744 Olgunun Analizi (Evaluation Of Endometrial Biopsy Results In Our Clinic; Analysis Of 744 Cases). Zeynep Kamil Tıp Bülteni. 2014;45:146-50. 6. Jetley S, Rana S, Jairajpuri ZS. Morphological spectrum of endometrial pathology in middle-aged women with atypical uterine bleeding: A study of 219 cases. J. Mid-life Health. 2013;4:216-20. 7. Çintesun E, Çintesun FNİ, Aslan BK, Uçar MG, Yarıkkaya E. Endometrial Örnekleme Sonuçlarımız: 655 Olgunun Analizi. Jinekoloji - Obstetrik ve Neonatoloji Tıp Dergisi 2017;14(2):56-9. 8. Aker SŞ, Yüce T, Acar D, Atabekoğlu CS. Anormal Uterin Kanaması olan Kadınlarda Endometrial Örnekleme Sonuçları: 765 Vakanın Retrospektif Analizi. Cukurova Medical Journal. 2015;40:306-10. 9. Williams AR, Brechin S, Porter AJL, Warner P, Critchley HOD. Factors affecting adequacy of pipelle and Tao Brush endometrial sampling. BJOG 2008;115:1028–36. 10. Bakour SH, Khan KS, Gupta JK. Controlled analysis of factors associated with insufficient sample on outpatient endometrial biopsy. BJOG 2000;107:1312–4.
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Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Original Research
Authors

Anıl Turhan Çakır This is me

İsa Şükrü Öz This is me

Burak Ün This is me

Publication Date June 8, 2020
Published in Issue Year 2020 Volume: 10 Issue: 2

Cite

APA Turhan Çakır, A., Öz, İ. Ş., & Ün, B. (2020). ENDOMETRİAL ÖRNEKLEME SONUÇLARIMIZ: 365 OLGUNUN ANALİZİ Results of Our Endometrial Samplings: Analysis of 365 Cases. Bozok Tıp Dergisi, 10(2), 28-32.
AMA Turhan Çakır A, Öz İŞ, Ün B. ENDOMETRİAL ÖRNEKLEME SONUÇLARIMIZ: 365 OLGUNUN ANALİZİ Results of Our Endometrial Samplings: Analysis of 365 Cases. Bozok Tıp Dergisi. June 2020;10(2):28-32.
Chicago Turhan Çakır, Anıl, İsa Şükrü Öz, and Burak Ün. “ENDOMETRİAL ÖRNEKLEME SONUÇLARIMIZ: 365 OLGUNUN ANALİZİ Results of Our Endometrial Samplings: Analysis of 365 Cases”. Bozok Tıp Dergisi 10, no. 2 (June 2020): 28-32.
EndNote Turhan Çakır A, Öz İŞ, Ün B (June 1, 2020) ENDOMETRİAL ÖRNEKLEME SONUÇLARIMIZ: 365 OLGUNUN ANALİZİ Results of Our Endometrial Samplings: Analysis of 365 Cases. Bozok Tıp Dergisi 10 2 28–32.
IEEE A. Turhan Çakır, İ. Ş. Öz, and B. Ün, “ENDOMETRİAL ÖRNEKLEME SONUÇLARIMIZ: 365 OLGUNUN ANALİZİ Results of Our Endometrial Samplings: Analysis of 365 Cases”, Bozok Tıp Dergisi, vol. 10, no. 2, pp. 28–32, 2020.
ISNAD Turhan Çakır, Anıl et al. “ENDOMETRİAL ÖRNEKLEME SONUÇLARIMIZ: 365 OLGUNUN ANALİZİ Results of Our Endometrial Samplings: Analysis of 365 Cases”. Bozok Tıp Dergisi 10/2 (June 2020), 28-32.
JAMA Turhan Çakır A, Öz İŞ, Ün B. ENDOMETRİAL ÖRNEKLEME SONUÇLARIMIZ: 365 OLGUNUN ANALİZİ Results of Our Endometrial Samplings: Analysis of 365 Cases. Bozok Tıp Dergisi. 2020;10:28–32.
MLA Turhan Çakır, Anıl et al. “ENDOMETRİAL ÖRNEKLEME SONUÇLARIMIZ: 365 OLGUNUN ANALİZİ Results of Our Endometrial Samplings: Analysis of 365 Cases”. Bozok Tıp Dergisi, vol. 10, no. 2, 2020, pp. 28-32.
Vancouver Turhan Çakır A, Öz İŞ, Ün B. ENDOMETRİAL ÖRNEKLEME SONUÇLARIMIZ: 365 OLGUNUN ANALİZİ Results of Our Endometrial Samplings: Analysis of 365 Cases. Bozok Tıp Dergisi. 2020;10(2):28-32.
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