SMALL INTESTINAL BACTERIAL OVERGROWTH AND INTESTINAL METHANOGEN OVERGROWTH IN A DOG WITH PARVOVIRAL GASTROENTERITIS: MEASUREMENT BY BREATH TESTING USING A LACTULOSE PROBE

Year 2024, Volume: 5 Issue: 2, 89 - 94

Kerem Ural , Hasan Erdoğan , Mehmet Gültekin , Serdar Paşa , Songül Erdoğan , Cansu Balıkçı , İlayda Tendar

https://doi.org/10.58833/bozokvetsci.1548421

Abstract

The aim of this case report is to detect small intestinal bacterial overgrowth (SIBO) and intestinal methanogen overgrowth (IMO) in a dog infected with Canine Parvovirus (CPV) using lactulose breath test and to evaluate the effects of CPV on intestinal permeability changes with this method. H2 and CH4 breath test analyses were performed to determine the presence of SIBO and/or IMO in the dog confirmed as CPV positive with antigen rapid test kit. Within this scope, four breath samples were collected from the patient at half-hour intervals using a pediatric masked gas collector apparatus. The collected samples were analyzed sequentially. H2 value was determined as 55 ppm in the first breath sample (#0). H2 value increased significantly to 168 ppm at 60th minute (#2). CH4 value was initially 19 ppm and reached 31 ppm at 60th minute. In addition, a second H2 peak of 132 ppm and a CH4 peak of 28 ppm were detected at 90 minutes. These findings indicated that SIBO and IMO were positive in the breath test. This case report emphasizes the importance of detecting and managing SIBO and IMO in dogs infected with CPV. The lactulose breath test is considered a promising tool in veterinary medicine for the diagnosis of intestinal permeability changes, leaky gut, and possible SIBO and IMO in dogs infected with CPV. Although further studies are needed, it was concluded that the detection of SIBO with this method may be critical for the prognosis and management of the infection.

Keywords

Breath test, Dog, Gastroenteritis, Parvovirus, SIBO

PARVOVİRAL GASTROENTERİTİSLİ BİR KÖPEKTE İNCE BAĞIRSAKTA AŞIRI BAKTERİYEL KOLONİZASYON VE İNTESTİNEL METANOJEN AŞIRI ÇOĞALMA: LAKTULOZ PROBU KULLANILARAK NEFES TESTİ İLE ÖLÇÜM

Abstract

Bu vaka raporunun amacı, Kanin Parvovirus (CPV) ile enfekte bir köpekte, laktuloz nefes testi kullanılarak ince bağırsaklarda aşırı bakteriyel çoğalma (SIBO) ile intestinel metanojen aşırı çoğalmanın (IMO) tespit edilmesi ve bu yöntemle CPV'nin intestinal permeabilite değişimlerine olan etkilerinin değerlendirilmesidir. Antijen hızlı test kiti ile CPV pozitif olarak doğrulanan köpekte SIBO ve/veya IMO mevcudiyetini belirlemek amacıyla H2 ve CH4 nefes testi analizleri gerçekleştirildi. Bu kapsamda, hastadan yarım saatlik aralıklarla dört adet nefes numunesi pediyatrik maskeli gaz toplayıcı aparat kullanılarak toplandı. Toplanan numuneler ardışık olarak analiz edildi. İlk nefes numunesinde (#0) H2 değeri 55 ppm olarak tespit edildi. 60. dakikada (#2) H2 değeri 168 ppm'e yükselerek belirgin bir artış gösterdi. CH4 değeri ise başlangıçta 19 ppm iken, 60. dakikada 31 ppm'e ulaştı. Ayrıca, 90. dakikada ikinci bir H2 zirvesi 132 ppm ve CH4 zirvesi 28 ppm olarak tespit edildi. Bu bulgular, nefes testinde SIBO'nun ve IMO’nun pozitif olduğunu gösterdi. Bu vaka raporu, CPV ile enfekte köpeklerde SIBO ve IMO 'nun tespiti ve yönetiminin önemini vurgulamaktadır. Laktuloz nefes testi, veteriner hekimlikte CPV ile enfekte köpeklerde intestinal permeabilite değişikliklerinin, geçirgen bağırsağın, muhtemel SİBO ile IMO’nun tanısında umut vadeden bir araç olarak görülmektedir. Daha ileri çalışmalara ihtiyaç duyulmakla birlikte, bu yöntemle SIBO'nun tespiti, enfeksiyonun prognozu ve yönetimi açısından kritik öneme sahip olabileceği sonucuna ulaşıldı.

Keywords

Gastroenteritis, Köpek, Nefes testi, Parvovirüs, SİBO

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