Research Article
BibTex RIS Cite

Türkiyede Yetişen Phedimus stoloniferus Türünün Uçucu Kimyasal Bileşimi ve Biyoaktivite Değerlendirilmesi

Year 2019, Volume: 6 Issue: 2, 585 - 593, 26.12.2019
https://doi.org/10.35193/bseufbd.633654

Abstract

Bu
araştırmada, Türkiye'de yetişen Phedimus stoloniferus'un (Crassulaceae)
esansiyel yağında (EO), SPME ve n-hekzan özütünün SPME'sindeki uçucu organik
bileşiklerin (VOC) GC-FID/MS ile analiz edilmiştir. P. stoloniferus'un
EO'daki uçucu bileşiklerin ana kimyasal sınıfını karboksilik asitler oluşturur
(%50.2).  P. stoloniferus'un SPME
ve heksan özütlerinin ve SPME’leri, ana bileşenlerinin aromatik bileşikler
(sırasıyla %51.9 ve %65.9) olduğunu gösterdi. 
P. stoloniferus'tan elde edilen EO, SPME ve  heksan özütlerinin SPME'sindeki  ana bileşikler sırasıyla n-Heksadekanoik asit
(%34.0), 1-metil-4-etilbenzen (%20.2) ve mesitilen (%28.8)’dir. P. stoloniferus'dan
elde edilen esansiyel yağlarda ve çözücü (n-heksan, metanol ve su) özütlerinde
antioksidan ve tirozinaz inhibisyonları da incelenmiştir. P. stoloniferus'un
metanol özütünde antioksidan aktivite en yüksek olarak (TEAC: 1.23± 0.04)
tespit edilmişken, en yüksek tirosinaz enzimi inhibisyonu ise sulu özütte (IC50:
0.168 ± 0.018) gözlendi.

References

  • [1] Chamberlain, D.F., In: Davis, P.H. (ed.) Sedum L., In Flora of Turkey and the East Aegean Islands, At the Edinburgh University Press: Edinburgh, Scotland. (1972). 4, 224-244.
  • [2] Alpınar, K., Sedum L. (2012). In Türkiye Bitkileri Listesi/Damarlı Bitkiler, Güner A., Aslan S., Ekim T., Vural M., Babaç M.T., Eds: Nezahat Gökyiğit Botanik Bahçesi ve Flora Araştırmaları Derneği Yayını: Istanbul, Turkey, 384-386.
  • [3] Uzunhisarcıklı, M.E, (2012). Scrophularia. In: Türkiye Bitkileri Listesi (Damarlı Bitkiler). eds: Güner, A, Aslan, S, Ekim, T, Vura,l M, Babaç, MBT, Nezahat Gökyiğit Botanik Bahçesi ve Flora Araştırmaları Derneği Yayını, İstanbul.
  • [4] Baytop T. (1999). Therapy with Medicinal Plants in Turkey-Past and Present, second edition, Istanbul, Nobel Publishers, 480.
  • [5] Zeybek, N., Zeybek, U. (1994). Farmasotik Botanik, Izmir, Turkey, Ege University Press. 390.
  • [6] Ertaş, A., Boğa, M., Yılmaz, A.M., Yeşil, Y., Haşimi, N.M., Kaya, Ş.M., Temel, H., Kolak, U. (2014). Chemical compositions by using LC-MS/MS and GC-MS and biological activities of Sedum sediforme (Jacq.). Journal Agric Food Chemistry, 62, 4601-4609.
  • [7] Yaylı, N., Yasar, A., Iskender, N.Y., Yaylı, N., Cansu, T.B., Coskuncelebi, K., Karaoğlu, S.A. (2010). Chemical constituents and antimicrobial activities of the essential oils from Sedum allidum var. bithynicum and S. spurium grown in Turkey. Pharmaceutical Biology, 48, 191-194.
  • [8] Mesicek N., Perpar M. (1973). Essential oils from the orpine Sedum maximum. Farmacevtski Vestnik, 24, 123-124.
  • [9] Romojaro, A., Botella, M.A,. Obon, C., Pretel, M.T. (2013). Nutritional and antioxidant properties of wild edible plants and their use as potential ingredients in the modern diet. International Journal of Food Sciences and Nutrition, 64, 944-952.
  • [10] Mavi, A., Terzi, Z., Ozgen, U., Yıldırım, A., Coskun, M. (2004). Antioxidant properties of some medicinal plants: Prangos ferulacea (Apiaceae), Sedum sempervivoides (Crassulaceae), Malva neglecta (Malvaceae), Cruciata taurica (Rubiaceae), Rosa pimpinellifolia (Rosaceae), Galium verum subsp. verum (Rubiaceae), Urtica dioica (Urticaceae). Biological and Pharmaceutical Bulletin, 27, 702-705.
  • [11] Stankovic, M., Radojevic, I., Curcic, M., Vasic, S., Topuzovic, M., Comic, L., Markovic, S. (2012). Evaluation of biological activities of goldmoss stonecrop (Sedum acre L.). Turkish Journal of Biology, 36, 580-588.
  • [12] Gendaram, O., Choi, Y.H., Kim, Y.S., Ryu, S.Y. (2011). Anti-oxidative and antibacterial constituents from Sedum hybridum. Natural Product Sciences, 17, 279-284.
  • [13] Renda, G., Özel, A., Barut, B., Korkmaz, B., Yaylı, N. (2018). In Vitro protective and enzyme inhibitory effects of Crataegus microphylla extracts against oxidative damage. Turkish Journal of Pharmaceutical Sciences, 15, 77-84.
  • [14] Yaylı, N., Fandaklı, S., Korkmaz, B., Barut, B., Renda, G., Erik, İ. (2018). Biological evaluation (antimicrobial, antioxidant, and enzyme inhibitions), total phenolic content and volatile chemical compositions of Caucasalia macrophylla (M. Bieb.) B. Nord. (Asteraceae). Journal of Essential Oil Bearing Plants, 21(5), 1359-1373.
  • [15] Renda, G., Tevek, F., Korkmaz, B., Yaylı, N. (2017). Comparison of the Alchemilla L. samples fromturkish herbal market with the european pharmacopoeia 8.0. FABAD Journal of Pharmaceutical Sciences, 42(3), 167-177.
  • [16] Renda, G., Kalaycı, Y., Korkmaz, B., Karaoğlu, Ş.A., Yaylı, N. (2017). Chemical composition and antimicrobial activity of the essential oils of Five Scrophularia L. species from Turkey. Records of Natural Products, 11,521-531.
  • [17] Yaylı, N., Çelik, G., Korkmaz, B., Çoşkunçelebi, K., Karaoğlu, Ş.A. (2016). Altitude variation in the composition of essential oils fatty acid methyl esters and antimicrobial activities of two subspecies of Primula vulgaris grown in Turkey. Natural Product Communications, 11(10), 1505-1510.
  • [18] Üçüncü, O., Karataş, Ş. M., Baltacı, C., Karaköse, M., Türkuçar, S. A. (2019). Volatile constituents and biological properties of essential oils from aerial parts of Gentiana gelida BIEB. Journal of Oleo Science, 68 (10), 1011-1017.
  • [19] Akar, Z., Burnaz, N. A. (2019). A new colorimetric method for CUPRAC assay with using of TLC plate. LWT, 112, doi:10.1016/j.lwt.2019.05.110, 1-7.
  • [20] Adams, R.P. (1995). Identification of essential oil components by gas chromatography/mass spectrometry. Allured Publishing Corporation, Carol Stream, IL.
  • [21] Apak, R., Guclu, K., Ozyürek, M., Karademir, S.E. (2004). Novel total antioxidant capacity index for dietary polyphenols and vitamins C and E, using their cupric ion reducing capability in the presence of neocuproine: CUPRAC method. Journal Agric Food Chemistry, 52(26), 7970-7981.
  • [22] Masuda, T., Yamashita, D., Takeda, Y., Yonemori, S. (2005). Screening for tyrosinase inhibitors among extracts of seashore plants and identification of potent inhibitors from Garcinia subelliptica. Journal Bioscience, Biotechnology and Biochemistry, 69, 197-201.
  • [23] Chen, Y.S., Liou, H.C., Chan, C.F. (2013). Tyrosinase inhibitory effect and antioxidative activities of fermented and ethanol extracts of Rhodiola rosea and Lonicera japonica. The Scientific World Journal, volume 2013, Article ID 612739, 5 pages.

Bioactivity Evaluation and Volatile Chemical Composition of Phedimus stoloniferus Species Grown in Turkey

Year 2019, Volume: 6 Issue: 2, 585 - 593, 26.12.2019
https://doi.org/10.35193/bseufbd.633654

Abstract

In this research, volatile organic compounds (VOCs)
in the essential oil (EO), SPME and SPME of n-hexane extract of Phedimus
stoloniferus
(Crassulaceae) grown in Turkey were determined by GC-FID/MS.
Major chemical class for the volatile compounds in the EO of P. stoloniferus
is carboxylic acids (50.2%). SPME and SPME of the hexane extracts of P.
stoloniferus
revealed aromatic compounds (51.9% and 65.9%, respectively) as
the main constituents. n-Hexadecanoic acid (34.0%), 1-methyl-4-ethylbenzene
(20.2%), and mesitylene (28.8%) were the major compounds in the EO, SPME and
SPME of hexane extract obtained from P. stoloniferus, respectively.  Antioxidant and tyrosinase inhibitions of the
essential oil and n-hexane, methanol, and water extracts obtained from P.
stoloniferus
were also studied. While the antioxidant activity was
determined to be highest in methanol extract (TEAC: 1.23±0.04), tyrosinase
enzyme inhibition was highest in the aqueous extract (IC50:
0.168±0.018) of P. stoloniferus.

References

  • [1] Chamberlain, D.F., In: Davis, P.H. (ed.) Sedum L., In Flora of Turkey and the East Aegean Islands, At the Edinburgh University Press: Edinburgh, Scotland. (1972). 4, 224-244.
  • [2] Alpınar, K., Sedum L. (2012). In Türkiye Bitkileri Listesi/Damarlı Bitkiler, Güner A., Aslan S., Ekim T., Vural M., Babaç M.T., Eds: Nezahat Gökyiğit Botanik Bahçesi ve Flora Araştırmaları Derneği Yayını: Istanbul, Turkey, 384-386.
  • [3] Uzunhisarcıklı, M.E, (2012). Scrophularia. In: Türkiye Bitkileri Listesi (Damarlı Bitkiler). eds: Güner, A, Aslan, S, Ekim, T, Vura,l M, Babaç, MBT, Nezahat Gökyiğit Botanik Bahçesi ve Flora Araştırmaları Derneği Yayını, İstanbul.
  • [4] Baytop T. (1999). Therapy with Medicinal Plants in Turkey-Past and Present, second edition, Istanbul, Nobel Publishers, 480.
  • [5] Zeybek, N., Zeybek, U. (1994). Farmasotik Botanik, Izmir, Turkey, Ege University Press. 390.
  • [6] Ertaş, A., Boğa, M., Yılmaz, A.M., Yeşil, Y., Haşimi, N.M., Kaya, Ş.M., Temel, H., Kolak, U. (2014). Chemical compositions by using LC-MS/MS and GC-MS and biological activities of Sedum sediforme (Jacq.). Journal Agric Food Chemistry, 62, 4601-4609.
  • [7] Yaylı, N., Yasar, A., Iskender, N.Y., Yaylı, N., Cansu, T.B., Coskuncelebi, K., Karaoğlu, S.A. (2010). Chemical constituents and antimicrobial activities of the essential oils from Sedum allidum var. bithynicum and S. spurium grown in Turkey. Pharmaceutical Biology, 48, 191-194.
  • [8] Mesicek N., Perpar M. (1973). Essential oils from the orpine Sedum maximum. Farmacevtski Vestnik, 24, 123-124.
  • [9] Romojaro, A., Botella, M.A,. Obon, C., Pretel, M.T. (2013). Nutritional and antioxidant properties of wild edible plants and their use as potential ingredients in the modern diet. International Journal of Food Sciences and Nutrition, 64, 944-952.
  • [10] Mavi, A., Terzi, Z., Ozgen, U., Yıldırım, A., Coskun, M. (2004). Antioxidant properties of some medicinal plants: Prangos ferulacea (Apiaceae), Sedum sempervivoides (Crassulaceae), Malva neglecta (Malvaceae), Cruciata taurica (Rubiaceae), Rosa pimpinellifolia (Rosaceae), Galium verum subsp. verum (Rubiaceae), Urtica dioica (Urticaceae). Biological and Pharmaceutical Bulletin, 27, 702-705.
  • [11] Stankovic, M., Radojevic, I., Curcic, M., Vasic, S., Topuzovic, M., Comic, L., Markovic, S. (2012). Evaluation of biological activities of goldmoss stonecrop (Sedum acre L.). Turkish Journal of Biology, 36, 580-588.
  • [12] Gendaram, O., Choi, Y.H., Kim, Y.S., Ryu, S.Y. (2011). Anti-oxidative and antibacterial constituents from Sedum hybridum. Natural Product Sciences, 17, 279-284.
  • [13] Renda, G., Özel, A., Barut, B., Korkmaz, B., Yaylı, N. (2018). In Vitro protective and enzyme inhibitory effects of Crataegus microphylla extracts against oxidative damage. Turkish Journal of Pharmaceutical Sciences, 15, 77-84.
  • [14] Yaylı, N., Fandaklı, S., Korkmaz, B., Barut, B., Renda, G., Erik, İ. (2018). Biological evaluation (antimicrobial, antioxidant, and enzyme inhibitions), total phenolic content and volatile chemical compositions of Caucasalia macrophylla (M. Bieb.) B. Nord. (Asteraceae). Journal of Essential Oil Bearing Plants, 21(5), 1359-1373.
  • [15] Renda, G., Tevek, F., Korkmaz, B., Yaylı, N. (2017). Comparison of the Alchemilla L. samples fromturkish herbal market with the european pharmacopoeia 8.0. FABAD Journal of Pharmaceutical Sciences, 42(3), 167-177.
  • [16] Renda, G., Kalaycı, Y., Korkmaz, B., Karaoğlu, Ş.A., Yaylı, N. (2017). Chemical composition and antimicrobial activity of the essential oils of Five Scrophularia L. species from Turkey. Records of Natural Products, 11,521-531.
  • [17] Yaylı, N., Çelik, G., Korkmaz, B., Çoşkunçelebi, K., Karaoğlu, Ş.A. (2016). Altitude variation in the composition of essential oils fatty acid methyl esters and antimicrobial activities of two subspecies of Primula vulgaris grown in Turkey. Natural Product Communications, 11(10), 1505-1510.
  • [18] Üçüncü, O., Karataş, Ş. M., Baltacı, C., Karaköse, M., Türkuçar, S. A. (2019). Volatile constituents and biological properties of essential oils from aerial parts of Gentiana gelida BIEB. Journal of Oleo Science, 68 (10), 1011-1017.
  • [19] Akar, Z., Burnaz, N. A. (2019). A new colorimetric method for CUPRAC assay with using of TLC plate. LWT, 112, doi:10.1016/j.lwt.2019.05.110, 1-7.
  • [20] Adams, R.P. (1995). Identification of essential oil components by gas chromatography/mass spectrometry. Allured Publishing Corporation, Carol Stream, IL.
  • [21] Apak, R., Guclu, K., Ozyürek, M., Karademir, S.E. (2004). Novel total antioxidant capacity index for dietary polyphenols and vitamins C and E, using their cupric ion reducing capability in the presence of neocuproine: CUPRAC method. Journal Agric Food Chemistry, 52(26), 7970-7981.
  • [22] Masuda, T., Yamashita, D., Takeda, Y., Yonemori, S. (2005). Screening for tyrosinase inhibitors among extracts of seashore plants and identification of potent inhibitors from Garcinia subelliptica. Journal Bioscience, Biotechnology and Biochemistry, 69, 197-201.
  • [23] Chen, Y.S., Liou, H.C., Chan, C.F. (2013). Tyrosinase inhibitory effect and antioxidative activities of fermented and ethanol extracts of Rhodiola rosea and Lonicera japonica. The Scientific World Journal, volume 2013, Article ID 612739, 5 pages.
There are 23 citations in total.

Details

Primary Language English
Journal Section Articles
Authors

Nuri Yıldırım 0000-0002-5396-8862

Publication Date December 26, 2019
Submission Date October 16, 2019
Acceptance Date December 10, 2019
Published in Issue Year 2019 Volume: 6 Issue: 2

Cite

APA Yıldırım, N. (2019). Bioactivity Evaluation and Volatile Chemical Composition of Phedimus stoloniferus Species Grown in Turkey. Bilecik Şeyh Edebali Üniversitesi Fen Bilimleri Dergisi, 6(2), 585-593. https://doi.org/10.35193/bseufbd.633654