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Nöral Yaşlanma ile İlişkili Süreçlerin Nöroplastisite Üzerine Etkisi

Year 2022, Volume: 5 Issue: 2, 303 - 311, 01.05.2022
https://doi.org/10.19127/bshealthscience.1021574

Abstract

Yaşlanma, nöronal plastisite mekanizmalarını doğrudan etkileyen ve hücresel süreçlerdeki değişikliklerle açıklanabilen bilişsel işlevlerdeki gerileme ile ilişkili bir süreçtir. Yaşlanma süreci beyin boyutunda küçülmeye, beyin vasküler sisteminde ve bilişsel işlevlerde bozukluklara sebep olmaktadır. Beyinde gerçekleşen küçülme ile birlikte moleküler seviyeden doku seviyesine kadar her düzeyde işlevsel değişiklikler meydana gelmektedir. Nöral plastisite mekanizmaları bilişsel fonksiyonları düzenlemekte; öğrenme ve hafıza gibi fonksiyonların devamlılığı ve işlevselliği üzerinde önemli bir rol oynamaktadır. İlgili süreçlerde yaşın ilerlemesine bağlı olarak önemli ölçüde azalma gözlenmektedir. Bu derleme çalışması ile doğal yaşlanma sürecinin nöral plastisite üzerine olan etkisi hipokampus, medial temporal lob ve prefrontal korteks yapıları üzerinden; davranışsal, morfolojik, hücresel ve moleküler yönleri ile tartışılarak; yaşlanmanın nöral plastisite üzerindeki etkisi ve yaşlanma ile ilişkili nöropatolojiler incelenecektir.

References

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Effects of Neural Aging Related Processes on Neuroplasticity

Year 2022, Volume: 5 Issue: 2, 303 - 311, 01.05.2022
https://doi.org/10.19127/bshealthscience.1021574

Abstract

Aging is a process associated with decline in cognitive functions that directly affects neuronal plasticity mechanisms and can be explained by changes in cellular processes. The aging process causes a reduction in brain size, disorders in the cerebral vascular system and cognitive functions. With the shrinkage in the brain, functional changes occur at all levels, from the molecular level to the tissue level. Neural plasticity mechanisms regulate cognitive functions; It plays an important role in the continuity and functionality of functions such as learning and memory. A significant decrease is observed in the related processes depending on the aging process. In this review, the effect of aging on neural plasticity and neuropathologies associated with aging will be examined focusing on the hippocampus, medial temporal lobe and prefrontal cortex structures by discussing behavioral, morphological, cellular and molecular aspects.

References

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There are 96 citations in total.

Details

Primary Language Turkish
Subjects Clinical Sciences, Health Care Administration
Journal Section Review
Authors

İrem Gülfem Albayrak 0000-0003-3218-7060

Elif Mutlu 0000-0002-2580-4043

Publication Date May 1, 2022
Submission Date November 10, 2021
Acceptance Date January 25, 2022
Published in Issue Year 2022 Volume: 5 Issue: 2

Cite

APA Albayrak, İ. G., & Mutlu, E. (2022). Nöral Yaşlanma ile İlişkili Süreçlerin Nöroplastisite Üzerine Etkisi. Black Sea Journal of Health Science, 5(2), 303-311. https://doi.org/10.19127/bshealthscience.1021574
AMA Albayrak İG, Mutlu E. Nöral Yaşlanma ile İlişkili Süreçlerin Nöroplastisite Üzerine Etkisi. BSJ Health Sci. May 2022;5(2):303-311. doi:10.19127/bshealthscience.1021574
Chicago Albayrak, İrem Gülfem, and Elif Mutlu. “Nöral Yaşlanma Ile İlişkili Süreçlerin Nöroplastisite Üzerine Etkisi”. Black Sea Journal of Health Science 5, no. 2 (May 2022): 303-11. https://doi.org/10.19127/bshealthscience.1021574.
EndNote Albayrak İG, Mutlu E (May 1, 2022) Nöral Yaşlanma ile İlişkili Süreçlerin Nöroplastisite Üzerine Etkisi. Black Sea Journal of Health Science 5 2 303–311.
IEEE İ. G. Albayrak and E. Mutlu, “Nöral Yaşlanma ile İlişkili Süreçlerin Nöroplastisite Üzerine Etkisi”, BSJ Health Sci., vol. 5, no. 2, pp. 303–311, 2022, doi: 10.19127/bshealthscience.1021574.
ISNAD Albayrak, İrem Gülfem - Mutlu, Elif. “Nöral Yaşlanma Ile İlişkili Süreçlerin Nöroplastisite Üzerine Etkisi”. Black Sea Journal of Health Science 5/2 (May 2022), 303-311. https://doi.org/10.19127/bshealthscience.1021574.
JAMA Albayrak İG, Mutlu E. Nöral Yaşlanma ile İlişkili Süreçlerin Nöroplastisite Üzerine Etkisi. BSJ Health Sci. 2022;5:303–311.
MLA Albayrak, İrem Gülfem and Elif Mutlu. “Nöral Yaşlanma Ile İlişkili Süreçlerin Nöroplastisite Üzerine Etkisi”. Black Sea Journal of Health Science, vol. 5, no. 2, 2022, pp. 303-11, doi:10.19127/bshealthscience.1021574.
Vancouver Albayrak İG, Mutlu E. Nöral Yaşlanma ile İlişkili Süreçlerin Nöroplastisite Üzerine Etkisi. BSJ Health Sci. 2022;5(2):303-11.