Research Article
BibTex RIS Cite

Investigation of Seroprevalence of Vaccine-Preventable Diseases in Medical School Students

Year 2025, Volume: 9 Issue: 3, 169 - 174, 20.12.2025

Abstract

Objective: Medical students are in the high-risk group regarding exposure to infectious diseases during their education. This study aimed to evaluate the seroprevalence of hepatitis A, hepatitis B, measles, rubella, mumps, mumps, and varicella viruses among the vaccine-preventable infectious diseases in the fourth, fifth and sixth-grade students of the Faculty of Medicine of our university.
Methods: The serologic tests performed for hepatitis A, hepatitis B, measles, rubella, mumps, mumps, and varicella in fourth, fifth, and sixth-grade students studying at the Faculty of Medicine in the 2024-2025 academic year were retrospectively analyzed. Student records were scanned retrospectively through the hospital information processing system, and HBsAg, Anti-HBs, Anti-HAV IgG, measles IgG, Rubella IgG, mumps IgG, and varicella IgG results performed between 01.10.2021-31.12.2024 were recorded. Data were analyzed with IBM SPSS for the Mac 26.0 program. (Armonk, NY: IBM Corp, USA)
Results: The mean age of 317 students was 22.5 ± 1.5 years; 47.6% were female and 52.4% were male. HBsAg, anti-HCV, and anti-HIV tests were negative in all students. Anti-HBs positivity was 71%, anti-HAV IgG positivity was 44%, measles IgG positivity was 67%, rubella IgG positivity was 98%, mumps IgG positivity was 88%, and varicella IgG positivity was 95%. The presence of incomplete vaccinations in final-year students was striking.
Conclusion: It is observed that the immunity levels of medical students against vaccine-preventable diseases are not at the desired level. Serologic screening of students before starting practical training and vaccinating those with deficient immunity is essential for protecting students and the patient population.

References

  • 1. World Health Organzaton (WHO). Global hepatts report 2024: acton for access n low- and mddle-ncome countres. Geneva: Last accessed date:: 24.01.2025. Avalable from: https://www.who.nt/publcatons//tem/9789240091672.
  • 2. Centers for Dsease Control and Preventon. Recommended Vaccnes for Healthcare Workers. Last accessed date: 24.01.2025. Avalable from: https://www.cdc.gov/vacc- nes-adults/recommended-vaccnes/ndex.html.
  • 3. Von Lnstow ML, Yde Nelsen A, Krkby N, et al. Immunty to vaccne-preventable dseases among paedatrc healthcare workers n Denmark, 2019. Euro Survell. 2021;26(17):2001167. do: 10.2807/1560-7917.ES.2021.26.17.2001167.
  • 4. Han SB, Park SH, Y Y, et al. Measles seroprevalence among healthcare workers n South Korea durng the post-elmnaton perod. Hum Vaccn Immunother. 2021;3;17(8):2517- 2521. do: 10.1080/21645515.2021.1888623.
  • 5. Gavola GC, Desa S. Immunzaton requrements n medcal school accredtaton standards. Vaccne. 2024;42(4):753-756. do:10.1016/j.vaccne.2023.04.026.
  • 6. World Health Organzaton. Vaccnaton n acute humantaran emergences: a framework for decson makng. Last accessed date: 24. 06.12.2024. Avalable from: http:// apps.who.nt/rs/btstream/10665/92462/1/WHO_IVB_13.07_eng.pdf.
  • 7. Tekn Yılmaz A. Chldhood Routne Vaccne Schedule and Immunzaton Practces. J Botechnol and Strategc Health Res. December 2024;8(3):148-162. do:10.34084/ bshr.1576419
  • 8. Babaoglu B, Fdancı I, Aksoy H, Ayhan Baser D. Evaluaton of hepatts A, hepatts B, hepat ts C, HIV, mumps, measles, rubella, and varcella mmunty status of health scences students. Interdscp Med J. 2024;15(53):137-43.
  • 9. Altın N, Ulusoy TÜ, Gürbüz Y, et al. Seroepdemology of measles, rubella, mumps, varcella, hepatts A and B vruses n healthcare workers: A cross-sectonal study from Turkey Turk J Cln Lab. 2024;4: 518-522.
  • 10. Çalık S, Tosun S, Tuncel Basoglu M, Sayın S.  e Investgaton of Seroprevalence of Measles, Rubella, Mumps, and Varcella n Medcal Students. FLORA. 2017;22(2):73-77. do:10.5578/ ora.61879.
  • 11. Cabadak H, Arman D, Dzbay M.  e Investgaton of Seroprevalence of Vaccne-Preventable Dseases n Medcal Students. FLORA. 2008;13(3):136-141.
  • 12. Republc of Türkye Mnstry of Health. General Drectorate of Publc Health Crcular on Rsk Group and HealthWorker Vaccnatons. Last accessed date: 01. 07.2025. Avalable from: https://hsgm.saglk.gov.tr/depo/brmler/as-le-onleneblr-hastalklar-db/dokumanlar/ Rsk_Grubu_ve_Saglk.pdf.

Tıp Fakültesi Öğrencilerinde Aşı ile Önlenebilir Hastalıkların Seroprevalansının Araştırılması

Year 2025, Volume: 9 Issue: 3, 169 - 174, 20.12.2025

Abstract

Amaç: Tıp Fakültesi öğrencileri eğitimleri sırasında bulaşıcı hastalıklara maruz kalma açısından yüksek risk grubundadır. Çalışmamızda üniversitemiz Tıp Fakültesi dördüncü, beşinci ve altıncı sınıf öğrencilerinin aşı ile önlenebilen enfeksiyon hastalıklarından olan; hepatit A, hepatit B, kızamık, kızamıkçık, kabakulak ve suçiçeği virüslerine karşı bağışıklık durumlarının değerlendirilmesi amaçlanmıştır.
Yöntemler: 2024-2025 eğitim öğretim yılında Tıp Fakültesinde öğrenim gören dördüncü, beşinci ve altıncı sınıf öğrencilerinde hepatit A, hepatit B, kızamık, kızamıkçık, kabakulak, kabakulak ve suçiçeği için yapılan serolojik testler retrospektif olarak analiz edildi. Öğrenci kayıtları hastane bilgi işlem sistemi üzerinden retrospektif olarak tarandı ve 01.10.2021-31.12.2024 tarihleri arasında yapılan HBsAg, Anti-HBs, Anti-HAV IgG, kızamık IgG, kızamıkçık IgG, kabakulak IgG ve suçiçeği IgG sonuçları kaydedildi. Veriler IBM SPSS for Mac 26.0 programı ile analiz edildi (Armonk, NY: IBM Corp, USA).
Bulgular: 317 öğrencinin ortalama yaşı 22,5 ± 1,5 yıldı; %47,6'sı kadın, %52,4'ü erkekti. HBsAg, anti-HCV ve anti-HIV testleri tüm öğrencilerde negatifti. Anti-HBs pozitifliği %71, anti-HAV IgG pozitifliği %44, kızamık IgG pozitifliği %67, kızamıkçık IgG pozitifliği %98, kabakulak IgG pozitifliği %88 ve suçiçeği IgG pozitifliği %95 idi. Son sınıf öğrencilerinde eksik aşılamaların varlığı dikkat çekiciydi.
Sonuç: Tıp öğrencilerinin aşı ile önlenebilir hastalıklara karşı bağışıklık düzeylerinin istenilen düzeyde olmadığı görülmektedir. Uygulamalı eğitime başlamadan önce öğrencilerin serolojik taramasının yapılması ve bağışıklığı yetersiz olanların aşılanması öğrencileri ve hasta popülasyonunu korumak için önemlidir.

References

  • 1. World Health Organzaton (WHO). Global hepatts report 2024: acton for access n low- and mddle-ncome countres. Geneva: Last accessed date:: 24.01.2025. Avalable from: https://www.who.nt/publcatons//tem/9789240091672.
  • 2. Centers for Dsease Control and Preventon. Recommended Vaccnes for Healthcare Workers. Last accessed date: 24.01.2025. Avalable from: https://www.cdc.gov/vacc- nes-adults/recommended-vaccnes/ndex.html.
  • 3. Von Lnstow ML, Yde Nelsen A, Krkby N, et al. Immunty to vaccne-preventable dseases among paedatrc healthcare workers n Denmark, 2019. Euro Survell. 2021;26(17):2001167. do: 10.2807/1560-7917.ES.2021.26.17.2001167.
  • 4. Han SB, Park SH, Y Y, et al. Measles seroprevalence among healthcare workers n South Korea durng the post-elmnaton perod. Hum Vaccn Immunother. 2021;3;17(8):2517- 2521. do: 10.1080/21645515.2021.1888623.
  • 5. Gavola GC, Desa S. Immunzaton requrements n medcal school accredtaton standards. Vaccne. 2024;42(4):753-756. do:10.1016/j.vaccne.2023.04.026.
  • 6. World Health Organzaton. Vaccnaton n acute humantaran emergences: a framework for decson makng. Last accessed date: 24. 06.12.2024. Avalable from: http:// apps.who.nt/rs/btstream/10665/92462/1/WHO_IVB_13.07_eng.pdf.
  • 7. Tekn Yılmaz A. Chldhood Routne Vaccne Schedule and Immunzaton Practces. J Botechnol and Strategc Health Res. December 2024;8(3):148-162. do:10.34084/ bshr.1576419
  • 8. Babaoglu B, Fdancı I, Aksoy H, Ayhan Baser D. Evaluaton of hepatts A, hepatts B, hepat ts C, HIV, mumps, measles, rubella, and varcella mmunty status of health scences students. Interdscp Med J. 2024;15(53):137-43.
  • 9. Altın N, Ulusoy TÜ, Gürbüz Y, et al. Seroepdemology of measles, rubella, mumps, varcella, hepatts A and B vruses n healthcare workers: A cross-sectonal study from Turkey Turk J Cln Lab. 2024;4: 518-522.
  • 10. Çalık S, Tosun S, Tuncel Basoglu M, Sayın S.  e Investgaton of Seroprevalence of Measles, Rubella, Mumps, and Varcella n Medcal Students. FLORA. 2017;22(2):73-77. do:10.5578/ ora.61879.
  • 11. Cabadak H, Arman D, Dzbay M.  e Investgaton of Seroprevalence of Vaccne-Preventable Dseases n Medcal Students. FLORA. 2008;13(3):136-141.
  • 12. Republc of Türkye Mnstry of Health. General Drectorate of Publc Health Crcular on Rsk Group and HealthWorker Vaccnatons. Last accessed date: 01. 07.2025. Avalable from: https://hsgm.saglk.gov.tr/depo/brmler/as-le-onleneblr-hastalklar-db/dokumanlar/ Rsk_Grubu_ve_Saglk.pdf.
There are 12 citations in total.

Details

Primary Language English
Subjects Infectious Diseases
Journal Section Research Article
Authors

Arzu Altunçekiç Yildirim 0000-0003-1141-9838

Şeyma Işikli 0009-0006-7676-2505

Celali Kurt 0000-0003-4419-4508

Hatun Öztürk Çerik 0000-0003-0277-5443

Submission Date August 26, 2025
Acceptance Date September 29, 2025
Early Pub Date December 15, 2025
Publication Date December 20, 2025
Published in Issue Year 2025 Volume: 9 Issue: 3

Cite

AMA Altunçekiç Yildirim A, Işikli Ş, Kurt C, Öztürk Çerik H. Investigation of Seroprevalence of Vaccine-Preventable Diseases in Medical School Students. J Biotechnol and Strategic Health Res. December 2025;9(3):169-174. doi:10.34084/bshr.1760448

Journal of Biotechnology and Strategic Health Research