Review

Sweeteners, Glucose Intolerance and Microbiota

Volume: 1 November 15, 2017
EN TR

Sweeteners, Glucose Intolerance and Microbiota

Abstract

The use of food additives in food production are inevitable in this modern world. Although only safe amount of them are approved, their safety have always been questioned. The effects of food additives on microbiota have not been investigated in detailed manner up to know. In this review the effects of sweeteners, a part of food additives, were reviewed and showed that they affect microbiota. As a rusult, nonnutritive syntetic sweeteners can lead to glucose intolerance by affecting microbiota and a part of sugar alcohols show probiotic like effects.

Keywords

References

  1. 1. Jin Y, Wu S, Zeng Z, Fu Z. Effects of environmental pollutants on gut microbiota. Environ Pollut. 2017; 222: 1-9.
  2. 2. Gültekin F. A'dan Z'ye Gıda Katkı Maddeleri. Server İletişim, 2014, İstanbul.
  3. 3. Suez J, Korem T, Zeevi D, Zilberman-Schapira G, Thaiss C.A, Maza O, Israeli D, Zmora N, Gilad S, Weinberger A, Kuperman Y, Harmelin A, Kolodkin-Gal I, Shapiro H, Halpern Z, Segal E, Elinav E. Artifi cial sweeteners induce glucose intolerance by altering the gut microbiota. Nature. 2014; 514: 181-186.
  4. 4. Palmnäs MS, Cowan TE, Bomhof MR, Su J, Reimer RA, Vogel HJ, Hittel DS, Shearer J. Low-dose aspartame consumption differentially affects gut microbiota-host metabolic interactions in the diet-induced obese rat. PLoS One. 2014; 14: 9(10)
  5. 5. Frankenfeld CL, Sikaroodi M, Lamb E, Shoemaker S, Gillevet PM. High-intensity sweetener consumption and gut microbiome content and predicted gene function in a cross-sectional study of adults in the United States. Ann Epidemiol. 2015; 25(10): 736-42
  6. 6. Daly K, Darby AC, Hall N, Nau A, Bravo D, Shirazi-Beechey SP. Dietary supplementation with lactose or artifi cial sweetener enhances swine gut Lactobacillus population abundance. Br J Nutr. 2014; 111 Suppl 1: 30-5
  7. 7. Abou-Donia MB, El-Masry EM, Abdel-Rahman AA, McLendon RE, Schiffman SS. Splenda alters gut microfl ora and increases intestinal p-glycoprotein and cytochrome p-450 in male rats, J Toxicol Environ Health A. 2008; 71(21): 1415–1429.
  8. 8. Beards E, Tuohy K, Gibson G. A human volunteer study to assess the impact of confectionery sweeteners on the gut microbiota composition. Br J Nutr. 2010 Sep;104(5):701-8. doi: 10.1017/ S0007114510001078. Epub 2010 Apr 7.

Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Review

Authors

Fatih Gültekin *
Sağlık Bilimleri Üniversitesi, Tıp Fakültesi Tıbbi Biyokimya AD, İstanbul
Türkiye

Manolya Eser Öner This is me
ALANYA ALAADDİN KEYKUBAT ÜNİVERSİTESİ, MÜHENDİSLİK FAKÜLTESİ, GIDA MÜHENDİSLİĞİ BÖLÜMÜ
Türkiye

Hasan Basri Savaş This is me
Sağlık Bilimleri Üniversitesi, Tıp Fakültesi Tıbbi Biyokimya Anabilim Dalı, İstanbul
Türkiye

Bora Doğan This is me
Alanya Alaaddin Keykubat Üniversitesi, Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Antalya
Türkiye

Publication Date

November 15, 2017

Submission Date

September 8, 2017

Acceptance Date

September 11, 2017

Published in Issue

Year 2017 Volume: 1

APA
Gültekin, F., Eser Öner, M., Savaş, H. B., & Doğan, B. (2017). Sweeteners, Glucose Intolerance and Microbiota. Journal of Biotechnology and Strategic Health Research, 1, 34-38. https://izlik.org/JA62ZE83PK
AMA
1.Gültekin F, Eser Öner M, Savaş HB, Doğan B. Sweeteners, Glucose Intolerance and Microbiota. J Biotechnol and Strategic Health Res. 2017;1:34-38. https://izlik.org/JA62ZE83PK
Chicago
Gültekin, Fatih, Manolya Eser Öner, Hasan Basri Savaş, and Bora Doğan. 2017. “Sweeteners, Glucose Intolerance and Microbiota”. Journal of Biotechnology and Strategic Health Research 1 (November): 34-38. https://izlik.org/JA62ZE83PK.
EndNote
Gültekin F, Eser Öner M, Savaş HB, Doğan B (November 1, 2017) Sweeteners, Glucose Intolerance and Microbiota. Journal of Biotechnology and Strategic Health Research 1 34–38.
IEEE
[1]F. Gültekin, M. Eser Öner, H. B. Savaş, and B. Doğan, “Sweeteners, Glucose Intolerance and Microbiota”, J Biotechnol and Strategic Health Res, vol. 1, pp. 34–38, Nov. 2017, [Online]. Available: https://izlik.org/JA62ZE83PK
ISNAD
Gültekin, Fatih - Eser Öner, Manolya - Savaş, Hasan Basri - Doğan, Bora. “Sweeteners, Glucose Intolerance and Microbiota”. Journal of Biotechnology and Strategic Health Research 1 (November 1, 2017): 34-38. https://izlik.org/JA62ZE83PK.
JAMA
1.Gültekin F, Eser Öner M, Savaş HB, Doğan B. Sweeteners, Glucose Intolerance and Microbiota. J Biotechnol and Strategic Health Res. 2017;1:34–38.
MLA
Gültekin, Fatih, et al. “Sweeteners, Glucose Intolerance and Microbiota”. Journal of Biotechnology and Strategic Health Research, vol. 1, Nov. 2017, pp. 34-38, https://izlik.org/JA62ZE83PK.
Vancouver
1.Fatih Gültekin, Manolya Eser Öner, Hasan Basri Savaş, Bora Doğan. Sweeteners, Glucose Intolerance and Microbiota. J Biotechnol and Strategic Health Res [Internet]. 2017 Nov. 1;1:34-8. Available from: https://izlik.org/JA62ZE83PK

Journal of Biotechnology and Strategic Health Research