Kas İskelet Sistemi Ağrılarında Proloterapi Enjeksiyonları

Abstract

Proloterapi, az miktarda irritan solüsyonun normal hücre ve doku büyümesini uyarmak amacıyla ağrılı, hasarlı veya dejenere olmuş tendon ve ligamentlerin yapışma bölgelerine (entezis) uygulandığı enjeksiyonları içeren rejeneratif bir tedavi yöntemidir. Bu yöntem kas iskelet sistemi kaynaklı ağrıların tedavisinde 80 yıldan uzun süredir kullanılmaktadır. Proloterapi’nin kas iskelet sistemi sorunlarında kullanımı, ağrının ligamentlerdeki zayıflama sonucu ortaya çıkan relaksasyona bağlı olduğu ve bu ligamentlerin tahriş edici, hücre proliferasyonunu uyarıcı solüsyonların enjeksiyonları ile güçlendirilebileceği düşüncesine dayandırılmaktadır.Ligament relaksasyonu; genel olarak ligament içeriğindeki liflerin dayanıklılığının bozulduğu durum olarak tanımlanmaktadır. İrritan solüsyonların enjeksiyonları ile tendon ve ligamentlerde fibroblast hiperplazisi, hücre proliferasyonu, kollojen lif çapında artış gibi histolojik yapısal değişikliklerin yanısıra tendon ve ligament gücünde artış da gözlenmektedir. Bu etki, yara iyileşme mekanizmasının tetiklenmesine bağlı oluşmaktadır.Proloterapi enjeksiyonlarının eklem ağrıları ve eklem laksitesi, kronik bel ağrısı, epikondilit, tendinopatiler, aşırı kullanım yaralanmaları gibi kas iskelet sistemi sorunlarındaki etkinliğini araştıran çalışmaların artması ile birlikte son dönemde bu rejeneratif tedavi yöntemine ilgi giderek artmaktadır. 

Keywords

• Proloterapi,kas iskelet sistemi ağrısı,tendon,ligament,laksite

Prolotherapy Injections for Musculoskeletal Pain

Abstract

Prolotherapy is a regenerative treatment method that involves injections of small amounts of an irritant solution to the site of painful, injured or degenerated tendon and ligament insertions (entheses) to promote growth of normal cells and tissues. It has been used in clinical practice for more than 80 years to treat various musculoskeletal pain. The use of prolotherapy in musculoskeletal problems is based on the idea that pain is due to relaxation caused by attenuation of the ligaments and that these ligaments can be strengthened by injections of irritating, cell proliferation stimulating solutions.Ligament relaxation; generally described as a condition in which the strength of the ligament fibers has become impaired. Histological structural changes such as fibroblast hyperplasia, cell proliferation, increase in collagen fiber diameter are observed in tendons and ligaments after injections of irritant solutions. İn addition to histological changes, increase in tendon and ligament strenght is also observed. This effect is due to triggering of wound healing mechanism.

With the increasing number of studies investigating the efficacy of prolotherapy injections in musculoskeletal problems such as joint pain and joint laxity, chronic low back pain, epicondylitis, tendinopathies, and overuse injuries, there is an increasing interest in this regenerative treatment method.

Keywords

• prolotherapy,musculoskeletal pain,tendon,ligament,laxity

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