Kas İskelet Sistemi Ağrılarında Proloterapi Enjeksiyonları

Year 2019, , 91 - 114, 30.09.2019

İlker Solmaz

https://doi.org/10.34084/bshr.571715

Cited By: 2

Abstract

Proloterapi, az
miktarda irritan solüsyonun normal hücre ve doku büyümesini uyarmak amacıyla ağrılı,
hasarlı veya dejenere olmuş tendon ve ligamentlerin yapışma bölgelerine
(entezis) uygulandığı enjeksiyonları içeren rejeneratif bir tedavi yöntemidir.
Bu yöntem kas iskelet sistemi kaynaklı ağrıların tedavisinde 80 yıldan uzun
süredir kullanılmaktadır. Proloterapi’nin kas iskelet sistemi sorunlarında
kullanımı, ağrının ligamentlerdeki zayıflama sonucu ortaya çıkan relaksasyona bağlı
olduğu ve bu ligamentlerin tahriş edici, hücre proliferasyonunu uyarıcı
solüsyonların enjeksiyonları ile güçlendirilebileceği düşüncesine
dayandırılmaktadır.Ligament
relaksasyonu; genel olarak ligament içeriğindeki liflerin dayanıklılığının
bozulduğu durum olarak tanımlanmaktadır. İrritan solüsyonların enjeksiyonları
ile tendon ve ligamentlerde fibroblast hiperplazisi, hücre proliferasyonu,
kollojen lif çapında artış gibi histolojik yapısal değişikliklerin yanısıra
tendon ve ligament gücünde artış da gözlenmektedir. Bu etki, yara iyileşme
mekanizmasının tetiklenmesine bağlı oluşmaktadır.Proloterapi
enjeksiyonlarının eklem ağrıları ve eklem laksitesi, kronik bel ağrısı,
epikondilit, tendinopatiler, aşırı kullanım yaralanmaları gibi kas iskelet
sistemi sorunlarındaki etkinliğini araştıran çalışmaların artması ile birlikte
son dönemde bu rejeneratif tedavi yöntemine ilgi giderek artmaktadır. 

Keywords

Proloterapi, kas iskelet sistemi ağrısı, tendon, ligament, laksite

Prolotherapy Injections for Musculoskeletal Pain

Abstract

Prolotherapy is a regenerative treatment method that involves
injections of small amounts of an irritant solution to the site of painful,
injured or degenerated tendon and ligament insertions (entheses) to promote
growth of normal cells and tissues. It has been used in clinical practice for
more than 80 years to treat various musculoskeletal pain. The use of
prolotherapy in musculoskeletal problems is based on the idea that pain is due
to relaxation caused by attenuation of the ligaments and that these ligaments
can be strengthened by injections of irritating, cell proliferation stimulating
solutions.Ligament relaxation; generally described as a condition in which the
strength of the ligament fibers has become impaired. Histological structural
changes such as fibroblast hyperplasia, cell proliferation, increase in
collagen fiber diameter are observed in tendons and ligaments after injections
of irritant solutions. İn addition to histological changes, increase in tendon
and ligament strenght is also observed. This effect is due to triggering of
wound healing mechanism.

With the increasing
number of studies investigating the efficacy of prolotherapy injections in
musculoskeletal problems such as joint pain and joint laxity, chronic low back
pain, epicondylitis, tendinopathies, and overuse injuries, there is an
increasing interest in this regenerative treatment method.

Keywords

prolotherapy, musculoskeletal pain, tendon, ligament, laxity

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