Epidemiology of COVID-19: What We Learn From Pandemic
Year 2020,
, 29 - 36, 30.04.2020
Asiye Uğraş Dikmen
,
Mediha Kına
Seçil Özkan
,
Mustafa Necmi İlhan
Abstract
The COVID-19 outbreak, which occurred as a result of the SARS-CoV-2 virus that spread in the city of Wuhan, Hubei province in late 2019, is a public health crisis. The virus is thought to be caused by bat. The disease is transmitted from person to person through droplets and contact. Incubation time is shown as 4-5 days (0-14 days). The most common symptoms are fever, dry cough, and shortness of breath. The disease can be severe and fatal in people with old age and comorbid disease. More fatality rates were shown in men than in women. The global fatality rate is known as 2-3%. As the age increases, the rate of fatality increases. Routine BCG vaccine policy is thought to reduce mortality. The diagnosis is made in possible cases by showing the virus in respiratory secretions by special molecular tests. In the presence of clinical suspicion, imaging methods such as chest radiography and computed tomography are used in treatment planning. Mainly supportive and empirical treatment is used and specific treatment and vaccine are not yet available. Effective use of personal protective equipment to reduce contact with people, isolation of precise and suspicious cases and protection from contamination is crucial to combating the epidemic.
References
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COVID-19 Epidemiyolojisi: Pandemiden Ne Öğrendik
Year 2020,
, 29 - 36, 30.04.2020
Asiye Uğraş Dikmen
,
Mediha Kına
Seçil Özkan
,
Mustafa Necmi İlhan
Abstract
2019’un sonunda Çin’in Hubei eyaleti Wuhan şehrinde ortaya çıkan ve yayılanSARS-CoV-2 virüsü sonucu meydana gelen COVID-19 pandemisihalen ciddi bir halk sağlığı problemi olarak etkisini sürdürmektedir. Virüsün yarasa kaynaklı olduğu düşünülmektedir. Hastalık damlacık ve temas yolu ile insandan insana bulaşmaktadır. İnkübasyon süresi ortalaması 4-5 gün (0-14 gün) olarak gösterilmiştir. En yaygın semptomları ateş, kuru öksürük ve nefes darlığıdır. Hastalık ileri yaş ve komorbid hastalığı olan kişilerde şiddetli ve mortal seyredebilmektedir. Erkeklerde daha fazla fatalite hızı gösterilmiştir. Fatalite hızı dünya genelinde %2-3 olarak değişmektedir. Yaş arttıkça fatalite hızı artmaktadır. Rutin BCG aşısı politikasının mortaliteyi azalttığı düşünülmektedir.
Teşhis olası vakalarda virüsün solunum sekresyonlarında özel moleküler testlerle gösterilmesi ile konur. Klinik şüphe varlığında tedavi planlamasında akciğer grafisi ve bilgisayarlı tomografi gibi görüntüleme yöntemleri kullanılmaktadır. Esas olarak destekleyii ve ampirik tedavi uygulanmakta olup spesifik tedavisi ve aşısı henüz yoktur. İnsanların temasının azaltılması, kesin ve şüpheli vakaların izolasyonu ve bulaştan korunmak için kişisel koruyucu ekipmanların etkin kullanımı salgın ile mücadelede çok büyük öneme sahiptir.
References
- 1. Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A Novel Coronavirus from Patients with Pneumonia in China, 2019. N Engl J Med. 2020;382(8):727-33.
- 2. Yin Y, Wunderink RG. MERS, SARS and other coronaviruses as causes of pneumonia. Respirology. 2018;23(2):130-7.
- 3. Gorbalenya AE, Baker SC, Baric RS, de Groot RJ, Drosten C, Gulyaeva AA, et al. <em>Severe acute respiratory syndrome-related coronavirus</em>: The species and its viruses – a statement of the Coronavirus Study Group. bioRxiv. 2020:2020.02.07.937862.
- 4. Lu R, Zhao X, Li J, Niu P, Yang B, Wu H, et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet. 2020;395(10224):565-74.
- 5. Zhou P, Yang X-L, Wang X-G, Hu B, Zhang L, Zhang W, et al. Discovery of a novel coronavirus associated with the recent pneumonia outbreak in humans and its potential bat origin. BioRxiv. 2020.
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- 8. Lam TT-Y, Shum MH-H, Zhu H-C, Tong Y-G, Ni X-B, Liao Y-S, et al. Identification of 2019-nCoV related coronaviruses in Malayan pangolins in southern China. bioRxiv. 2020:2020.02.13.945485.
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- 12. Mission RotW-CJ, (COVID-19) oCD. https://www.who.int/docs/default-source/coronaviruse/who-china-joint-mission-on-covid-19-final-report.pdf Erişim Tarihi:1.04.2020.
- 13. Chen H, Guo J, Wang C, Luo F, Yu X, Zhang W, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. The Lancet. 2020;395(10226):809-15.
- 14. WHO. Coronavirus diease(COVID-19) situation reports.2020.https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200211-sitrep-22-ncov.pdf?sfvrsn=fb6d49b12 Erişim Tarihi:01.04.2020.
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https://who.maps.arcgis.com/apps/opsdashboard/index.html#/a19d5d1f86ee4d99b013eed5f637232d Erişim Tarihi.01.04.2020.
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- 20. Chiu WK, Cheung PC, Ng KL, Ip PL, Sugunan VK, Luk DC, et al. Severe acute respiratory syndrome in children: experience in a regional hospital in Hong Kong. Pediatr Crit Care Med. 2003;4(3):279-83.
- 21. Zou L, Ruan F, Huang M, Liang L, Huang H, Hong Z, et al. SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients: N Engl J Med. 2020 Mar 19;382(12):1177-1179. doi: 10.1056/NEJMc2001737. Epub 2020 Feb 19.
- 22. Liu Y, Yan LM, Wan L, Xiang TX, Le A, Liu JM, et al. Viral dynamics in mild and severe cases of COVID-19. Lancet Infect Dis. 2020.
- 23. WHO.Health Topics. Coronavirus. https://www.who.int/health-topics/coronavirus#tab=tab_3 Erişim Tarihi 01.04.2020.
- 24. Wu Z, McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention. JAMA. 2020.
- 25. Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395(10229):1054-62.
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- 30. Miller A, Reandelar M, Fasciglione K, Roumenova V, Li Y, Otazu G. Correlation between universal BCG vaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study2020.
- 31. Jin Y-H, Cai L, Cheng Z-S, Cheng H, Deng T, Fan Y-P, et al. A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version). Mil Med Res. 2020;7(1):4.
- 32. Yu F, Du L, Ojcius DM, Pan C, Jiang S. Measures for diagnosing and treating infections by a novel coronavirus responsible for a pneumonia outbreak originating in Wuhan, China. Microbes and Infection. 2020.
- 33. Lin C, Ye R, Xia YL. A meta-analysis to evaluate the effectiveness of real-time PCR for diagnosing novel coronavirus infections. Genet Mol Res. 2015;14(4):15634-41.
- 34. Infectious Diseases Society of America. COVID-19 Prioritization of Diagnostic Testing. https://www.idsociety.org/globalassets/idsa/public-health/covid-19-prioritization-of-dx-testing.pdf Erişim Tarihi:01.04.2020.