Malezya’da Bitkilerin Erkek Doğurganlık Arttırıcı Özelliklerine Yönelik Hayvan Çalışmaları: Son 16 Yılın Bir Değerlendirmesi

Year 2017, Volume: 1 Issue: 1, 17 - 23, 06.06.2017

Redzuan Nul Hakim Abdul Razak Muhammad Lokman Md Isa Afzan Mat Yusof Azantee Yazmie Abdul Wahab Hussin Muhammad Roszaman Ramli

Abstract

İnfertilite, ulusal ve küresel önemi olan ciddi bir halk sağlığı konusudur. İnfertilite prevalansının artıyor olması endişe
verici bir senaryodur. Doğal ürünlerden erkeklerde fertiliteyi arttırıcı ajanlar arayışında bitki kökenli ilaçların önemi uzun
bir süredir bilinmektedir. Bu çalışma, erkek fertilite verimliliğini arttıran çeşitli bitki araştırmaları yaklaşımlarını özetlemektedir
ki bu çalışılmaların bir kısmında bitkiler bizzat kullanılmıştır, bazılarında bitkiden bileşiklerin izole edilmesi için
ekstrakt elde edilmiştir, diğer bir kısmı ise farklı hayvan modellerinde denenen aktik bileşiklerdir. Araştırılan literatür,
2000’li yıllardan 2016’ya 16 yıllık çalışmaları kapsamakta olup bunlarda yaklaşık 12 bitkinin erkek fertilite aktivitesine
etkilerini gösterilmiştir. Sonuç olarak, bu araştırma, dünyadaki erkeklerde doğurganlık sorununu iyileştirmede gelecekteki
bitki uyumu keşfi ne odaklanmada diğer araştırmacılara yardımcı olacaktır.

Keywords

Herbal bitki, üreme sistemi, doğurganlık, hayvan çalışmaları

Animal Studies on Male Fertility Enhancing Properties of Plants In Malaysia: A Review of The Past 16 Years

Abstract

Infertility is an issue of global and national public health concern. It is a worrying scenario with increasing number of
prevalence in infertility. The importance of drugs of plant origin in the quest of fertility enhancing agents for the male
from natural products has long been recognized. The present review is an attempt to summarize the fertility enhancing
plants with various approaches which are: part of plant have been used, type of extract for isolating the compounds,
different isolated compounds (active principles) along with different animal model used. The literature covered is of
16 years from 2000 to 2016 for around 12 plants showing improving fertility activity in males. In conclusion, this
review will help other researchers in focusing future herb based drug discovery in improving fertility problem among
male across the globe

Keywords

herbal plant, reproductive system, fertility, animal study

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