Quantitative Evaluation of FDG PET Imaging

Öz

Positron emission tomography / computed tomography has an increasing use for diagnosis, staging, prognosis and response to treatment in oncological cases. The major advantage of PET is the ability to measure radiopharmaceutical uptake and it gives digital results in the form of standardized uptake value (SUV) . Semi-quantitative measurements (SUV) obtained from 18F-FDG PET / CT findings are the most important parameters in distinguishing between benign and malignant lesions. SUV measurement differences change the clinical efficacy of PET-based measurement, a semi-quantitative imaging biomarker for treatment response and treatment planning in oncologic patients.

Anahtar Kelimeler

• Positron emission tomography
• computed tomography
• standardized uptake value

FDG PET Görüntülemelerin Kantitatif Değerlendirilmesi

Öz

Pozitron emisyon tomografi/ bilgisayarlı tomografi onkolojik vakalarda tanı, evreleme, prognoz ve tedaviye yanıt için giderek artan kullanım alanına sahiptir. PET’in en büyük avantajı radyofarmasötik uptake’ini ölçebilmek ve en çok kullanılan parametre olan standardize uptake değeri (SUV) şeklinde sayısal sonuç vermesidir. SUV hesaplamaları rekonstrükte edilmiş PET ve BT görüntülerinden elde edilir. 18F-FDG PET/BT bulgularından elde edilen semikantitatif ölçümler (SUV) benign-malign lezyon ayırımında en önemli parametrelerdir. SUV ölçüm farklılıkları, onkolojik hastalarda tedavi yanıtı ve tedavi planlaması için yarı kantitatif bir görüntüleme biyobelirteci olan PET tabanlı ölçümün klinik etkinliğini değiştirir.

Anahtar Kelimeler

• PET/BT
• malignite
• SUV

Kaynakça

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