Investigation of the Association Between Motor Functions with Quality of Life and Daily Living Activities in Children with Acute Lymphoblastic Leukemia

Abstract

Objective: The aim of the present study was to investigate association between motor functions and quality of life level and activities of daily living (ADL) in children with acute lymphoblastic leukemia (ALL) receiving maintenance chemotherapy. Materials and Methods: The present study conducted at Hacettepe University Children Hospital. Children diagnosed with ALL and continue to maintenance chemotherapy, between the age of 4 to 15 years were included. Motor functions were assessed using The Bruininks-Oseretsky Test of Motor Proficiency-Second Edition Short Form, grip strength, the 9-Hole Peg Test, and the 30-second Sit to Stand Test. The Pediatric Quality of Life Questionnaire (PedsQL)-Cancer Module was used to determine quality of life level. The functional independent measure for children (WeeFIM) was used to determine ADL. Results: A total of 32 (Girl: 15/Boy: 17) children were included in the present study. The mean age of the children was 8.64±3.38 years. According to the correlation analysis, the 30-second Sit to Stand Test score and bilateral coordination score were moderately correlated with the PedsQL-Cancer Module (p˂0.05). The WeeFIM score was moderate to highly associated with The Bruininks-Oseretsky Test of Motor Proficiency-Second Edition Short Form total score, grip strength, and the 9-Hole Peg Test score (p˂0.05). Conclusion: Increase in gross and fine motor functions provide to improve in functionality in daily life and quality of life level in children with ALL when receiving chemotherapy. For this reason, children diagnosed with ALL should be followed in terms of motor functions.

Keywords

• Acute lymphoblastic leukemia
• Children
• Functional performance
• Quality of life.

Akut Lenfoblastik Lösemili Çocuklarda Motor Fonksiyonlar ile Yaşam Kalitesi ve Günlük Yaşam Aktiviteleri Arasındaki İlişkinin Araştırılması

Abstract

Giriş ve Amaç: Çalışmamızın amacı, idame kemoterapisi alan akut lenfoblastik lösemili (ALL) çocuklarda motor fonksiyonlar ile yaşam kalitesi ve günlük yaşam aktiviteleri (GYA) arasındaki ilişkinin araştırılmasıydı. Gereç ve Yöntemler: Çalışmamız, Hacettepe Üniversitesi Çocuk Hastanesi’nde gerçekleştirildi. Çalışmaya ALL tanısı alan ve idame kemoterapisine devam eden, 4 ve 15 yaşları arasındaki çocuklar dahil edildi. Motor fonksiyonlar, Bruininks-Oseretsky Motor Yeterlik Testi-2. Versiyon Kısa Formu, kavrama kuvveti, 9-Delikli Peg Testi ve 30-saniye Otur-Kalk Testi ile değerlendirildi. Çocuklar İçin Yaşam Kalitesi Ölçeği (ÇİYKÖ)-Kanser Modülü yaşam kalitesi düzeyini belirlemede kullanıldı. Çocuklar İçin Fonksiyonel Bağımsızlık Ölçeği (WeeFIM) GYA düzeyini değerlendirmede kullanıldı. Bulgular: Çalışmamıza toplam 32 çocuk (Kız: 15/Erkek: 17) dahil edildi. Çocukların ortalama yaşı 8,64±3,38 yıldı. Korelasyon analizlerine göre, 30-saniye Otur-Kalk Testi ve bilateral koordinasyon skoru, ÇİYKÖ-Kanser Modülü skoruyla orta derecede koreleydi (p˂0,05). WeeFIM toplam puanı ise Bruininks-Oseretsky Motor Yeterlik Testi-2. Versiyon Kısa Formu toplam puanı, kavrama kuvveti ve 9-Delikli Peg Testi skoru ile orta-yüksek derecede ilişkili bulundu (p˂0,05). Sonuç: ALL’li çocukların kemoterapi aldıkları dönemde motor becerilerindeki artış, günlük hayattaki fonksiyonelliğin ve yaşam kalitelerinin gelişmesi ile ilişkilidir. Bu sebeple, ALL tanısı almış çocuklar motor beceriler açısından dikkatli takip edilmelidir.

Keywords

• Akut lenfoblastik lösemi
• çocuk
• fonksiyonel performans
• yaşam kalitesi

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