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Diabetes mellituslu hastalarda koroner sinüs gerginliğinin değerlendirilmesi

Year 2021, Volume: 8 Issue: 1, 100 - 106, 31.12.2020
https://doi.org/10.34087/cbusbed.807737

Abstract

Arka plan: Diabetes mellitus (DM) önemli bir halk sağlığı sorunu olmaya devam etmektedir. Eşlik eden küçük ve büyük damar hastalıkları, yüksek morbidite ve mortalite ile ilişkili organ disfonksiyonuna yol açar. Bu çalışma, koroner sinüs gerilmesinin (stain) değerlendirilmesi ile diyabetin kardiyak venöz sistem üzerindeki etkisini ele almıştır.
Yöntemler: Kalp yetersizliği ve kalp kapak patolojisi dışlanan 49 DM'li ve 53 DM'siz hasta çalışmaya dahil edildi. Her iki grupta da koroner sinüs gerilmesi (CSS) ekokardiyografi ile değerlendirildi. Ek olarak, DM'nin arteriyel sistem üzerindeki etkilerini değerlendirmek için her iki grupta aort gerilmesi (AS) değerlendirildi.
Sonuçlar: CSS hasta grubunda 113.16 ± 17.89, kontrol grubunda 165.12 ± 19.30 idi. Hastaların ve kontrollerin ortalama CSS'si arasında anlamlı bir fark gözlemledik (p <0.001). AS hasta grubunda 4,85 ± 1,31 ve kontrol grubunda 10,60 ± 2,64 idi. AS, DM ve kontrol grupları arasında istatistiksel olarak farklıydı (p <0,001).
Sonuç: Bu çalışmada, DM'nin arteriyel sistem üzerindeki etkileri AS tarafından değerlendirilmiş ve sonuçlar önceki araştırma ve yayınlarla uyumlu görünmektedir. Koroner sinüsün ekokardiyografik değerlendirmesi, DM hastalarında kardiyak venöz sistemde bir değişiklik olduğunu düşündürmektedir.

References

  • 1- American Diabetes Association. Diagnosis and classification of Diabetes Mellitus. Diabetes Care 2004; 27: 5–14.
  • 2- Kohner EM & Dollery CT (1975): Diabetic retinopathy. In: Keen, H & Jarrett, J (eds.) Complications of Diabetes. Arnold Publisher, London: 29–32.
  • 3- Tan L, Qi B, Yu T, Wang C. Incidence and risk factors for venous thromboembolism following surgical treatment of fractures below the hip: a meta-analysis. Int Wound J. 2016;13(6):1359-1371. doi:10.1111/iwj.12533
  • 4- Alonso C, Leclercq C, d'Allonnes FR, et al. Six year experience of transvenous left ventricular lead implantation for permanent biventricular pacing in patients with advanced heart failure: technical aspects. Heart. 2001;86(4):405-410. doi:10.1136/heart.86.4.405.
  • 5- Gerber TC, Kantor B, Keelan PC, Hayes DL, Schwartz RS, Holmes DR. The Coronary Venous System: An Alternate Portal to the Myocardium for Diagnostic and Therapeutic Procedures in Invasive Cardiology. Curr Interv Cardiol Rep. 2000;2(1):27-37.
  • 6- Grzybiak M. Morphology of the CS and contemporary cardiac electrophysiology. Folia Morphol (Warsz) 1996;55:272–3.
  • 7- von Lüdinghausen M. Clinical anatomy of cardiac veins, Vv. cardiacae. Surg Radiol Anat. 1987;9(2):159-168. doi:10.1007/BF02086601.
  • 8- Akcay S, Turker Y, Kobat MA, Cetin N, Bilge AR, Tezcan UK. Evaluation of coronary sinus strain in patients with dipper and nondipper hypertension. Blood Press Monit. 2014;19(6):320-326. doi:10.1097/MBP.0000000000000065
  • 9- Aslan AN, Ayhan H, Çiçek ÖF, et al. Relationship between aortic stiffness and the left ventricular function in patients with prediabetes. Intern Med. 2014;53(14):1477-1484. doi:10.2169/internalmedicine.53.1720
  • 10- Eren M, Gorgulu S, Uslu N, Celik S, Dagdeviren B, Tezel T. Relation between aortic stiffness and left ventricular diastolic function in patients with hypertension, diabetes, or both. Heart. 2004;90(1):37-43. doi:10.1136/heart.90.1.37
  • 11- Çiftel M, Ertuğ H, Parlak M, Akçurin G, Kardelen F. Investigation of endothelial dysfunction and arterial stiffness in children with type 1 diabetes mellitus and the association with diastolic dysfunction. Diab Vasc Dis Res. 2014;11(1):19-25. doi:10.1177/1479164113508564
  • 12- Mahfouz Badran H, Elnoamany M. Impact of type 2 diabetes mellitus on aortic elastic properties in normotensive diabetes: Doppler tissue imaging study. J Am Soc Echocardiogr. 2006;19(12):1471-1481. doi:10.1016/j.echo.2006.06.004
  • 13- Stahrenberg R, Edelmann F, Mende M, et al. Association of glucose metabolism with diastolic function along the diabetic continuum [published correction appears in Diabetologia. 2011 Apr;54(4):990. Schönbrunn, L [added]]. Diabetologia. 2010;53(7):1331-1340. doi:10.1007/s00125-010-1718-8
  • 14- Bajraktari G, Qirko S, Rexhepaj N, et al. Non-insulin dependent diabetes as an independent predictor of asymptomatic left ventricular diastolic dysfunction. Croat Med J. 2005;46(2):225-231.
  • 15- Annonu AK, Fattah AA, Mokhtar MS, Ghareeb S, Elhendy A. Left ventricular systolic and diastolic functional abnormalities in asymptomatic patients with non-insulin-dependent diabetes mellitus. J Am Soc Echocardiogr. 2001;14(9):885-891. doi:10.1067/mje.2001.112892

Evaluation of Coronary Sinus Strain in Patients with Diabetes Mellitus

Year 2021, Volume: 8 Issue: 1, 100 - 106, 31.12.2020
https://doi.org/10.34087/cbusbed.807737

Abstract

Background: Diabetes mellitus (DM) remains a major public health problem. The accompanying small and large vessel diseases lead to organ system dysfunction associated with a high morbidity and mortality This study adressed the effect of diabetes on cardiac venous system by assessment of the coronary sinus strain.
Methods: 49 patients with and 53 without DM were included in the study, whose heart failure and heart valve pathology were excluded. Coronary sinüs strain (CSS) was evaluated with echocardiography in both groups. In addition, the aortic strain (AS) was assessed in both groups to evaluate the effects of DM on the arterial system.
Results: CSS was 113.16±17.89 in the patient group and 165.12±19.30 in the control group. We observed a significant difference between the mean CSS of the patients and the controls (p <0.001). AS was 4.85±1.31 in the patient group and 10.60±2.64 in the control group. AS was statistically different between DM and control groups (p <0.001).
Conclusion: In the present study, the effects of DM on arterial system were evaluated by AS and results appear consistent with prior research and publications. The echocardiographic evaluation of the coronary sinus suggest an alteration of the cardiac venous system in DM patients.

References

  • 1- American Diabetes Association. Diagnosis and classification of Diabetes Mellitus. Diabetes Care 2004; 27: 5–14.
  • 2- Kohner EM & Dollery CT (1975): Diabetic retinopathy. In: Keen, H & Jarrett, J (eds.) Complications of Diabetes. Arnold Publisher, London: 29–32.
  • 3- Tan L, Qi B, Yu T, Wang C. Incidence and risk factors for venous thromboembolism following surgical treatment of fractures below the hip: a meta-analysis. Int Wound J. 2016;13(6):1359-1371. doi:10.1111/iwj.12533
  • 4- Alonso C, Leclercq C, d'Allonnes FR, et al. Six year experience of transvenous left ventricular lead implantation for permanent biventricular pacing in patients with advanced heart failure: technical aspects. Heart. 2001;86(4):405-410. doi:10.1136/heart.86.4.405.
  • 5- Gerber TC, Kantor B, Keelan PC, Hayes DL, Schwartz RS, Holmes DR. The Coronary Venous System: An Alternate Portal to the Myocardium for Diagnostic and Therapeutic Procedures in Invasive Cardiology. Curr Interv Cardiol Rep. 2000;2(1):27-37.
  • 6- Grzybiak M. Morphology of the CS and contemporary cardiac electrophysiology. Folia Morphol (Warsz) 1996;55:272–3.
  • 7- von Lüdinghausen M. Clinical anatomy of cardiac veins, Vv. cardiacae. Surg Radiol Anat. 1987;9(2):159-168. doi:10.1007/BF02086601.
  • 8- Akcay S, Turker Y, Kobat MA, Cetin N, Bilge AR, Tezcan UK. Evaluation of coronary sinus strain in patients with dipper and nondipper hypertension. Blood Press Monit. 2014;19(6):320-326. doi:10.1097/MBP.0000000000000065
  • 9- Aslan AN, Ayhan H, Çiçek ÖF, et al. Relationship between aortic stiffness and the left ventricular function in patients with prediabetes. Intern Med. 2014;53(14):1477-1484. doi:10.2169/internalmedicine.53.1720
  • 10- Eren M, Gorgulu S, Uslu N, Celik S, Dagdeviren B, Tezel T. Relation between aortic stiffness and left ventricular diastolic function in patients with hypertension, diabetes, or both. Heart. 2004;90(1):37-43. doi:10.1136/heart.90.1.37
  • 11- Çiftel M, Ertuğ H, Parlak M, Akçurin G, Kardelen F. Investigation of endothelial dysfunction and arterial stiffness in children with type 1 diabetes mellitus and the association with diastolic dysfunction. Diab Vasc Dis Res. 2014;11(1):19-25. doi:10.1177/1479164113508564
  • 12- Mahfouz Badran H, Elnoamany M. Impact of type 2 diabetes mellitus on aortic elastic properties in normotensive diabetes: Doppler tissue imaging study. J Am Soc Echocardiogr. 2006;19(12):1471-1481. doi:10.1016/j.echo.2006.06.004
  • 13- Stahrenberg R, Edelmann F, Mende M, et al. Association of glucose metabolism with diastolic function along the diabetic continuum [published correction appears in Diabetologia. 2011 Apr;54(4):990. Schönbrunn, L [added]]. Diabetologia. 2010;53(7):1331-1340. doi:10.1007/s00125-010-1718-8
  • 14- Bajraktari G, Qirko S, Rexhepaj N, et al. Non-insulin dependent diabetes as an independent predictor of asymptomatic left ventricular diastolic dysfunction. Croat Med J. 2005;46(2):225-231.
  • 15- Annonu AK, Fattah AA, Mokhtar MS, Ghareeb S, Elhendy A. Left ventricular systolic and diastolic functional abnormalities in asymptomatic patients with non-insulin-dependent diabetes mellitus. J Am Soc Echocardiogr. 2001;14(9):885-891. doi:10.1067/mje.2001.112892
There are 15 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Araştırma Makalesi
Authors

İbrahim Halil ÖZDEMIR 0000-0003-3953-4387

Ugur TEZCAN This is me 0000-0002-2445-8089

Publication Date December 31, 2020
Published in Issue Year 2021 Volume: 8 Issue: 1

Cite

APA ÖZDEMIR, İ. H., & TEZCAN, U. (2020). Evaluation of Coronary Sinus Strain in Patients with Diabetes Mellitus. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, 8(1), 100-106. https://doi.org/10.34087/cbusbed.807737
AMA ÖZDEMIR İH, TEZCAN U. Evaluation of Coronary Sinus Strain in Patients with Diabetes Mellitus. CBU-SBED: Celal Bayar University-Health Sciences Institute Journal. December 2020;8(1):100-106. doi:10.34087/cbusbed.807737
Chicago ÖZDEMIR, İbrahim Halil, and Ugur TEZCAN. “Evaluation of Coronary Sinus Strain in Patients With Diabetes Mellitus”. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 8, no. 1 (December 2020): 100-106. https://doi.org/10.34087/cbusbed.807737.
EndNote ÖZDEMIR İH, TEZCAN U (December 1, 2020) Evaluation of Coronary Sinus Strain in Patients with Diabetes Mellitus. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 8 1 100–106.
IEEE İ. H. ÖZDEMIR and U. TEZCAN, “Evaluation of Coronary Sinus Strain in Patients with Diabetes Mellitus”, CBU-SBED: Celal Bayar University-Health Sciences Institute Journal, vol. 8, no. 1, pp. 100–106, 2020, doi: 10.34087/cbusbed.807737.
ISNAD ÖZDEMIR, İbrahim Halil - TEZCAN, Ugur. “Evaluation of Coronary Sinus Strain in Patients With Diabetes Mellitus”. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 8/1 (December 2020), 100-106. https://doi.org/10.34087/cbusbed.807737.
JAMA ÖZDEMIR İH, TEZCAN U. Evaluation of Coronary Sinus Strain in Patients with Diabetes Mellitus. CBU-SBED: Celal Bayar University-Health Sciences Institute Journal. 2020;8:100–106.
MLA ÖZDEMIR, İbrahim Halil and Ugur TEZCAN. “Evaluation of Coronary Sinus Strain in Patients With Diabetes Mellitus”. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, vol. 8, no. 1, 2020, pp. 100-6, doi:10.34087/cbusbed.807737.
Vancouver ÖZDEMIR İH, TEZCAN U. Evaluation of Coronary Sinus Strain in Patients with Diabetes Mellitus. CBU-SBED: Celal Bayar University-Health Sciences Institute Journal. 2020;8(1):100-6.