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Evaluation of Pediatric Patients Admitted to the Hospital for Drug Intoxication

Year 2024, Volume: 11 Issue: 3, 279 - 286, 30.09.2024
https://doi.org/10.34087/cbusbed.1340460

Abstract

ÖZ
Giriş ve Amaç: İlaç zehirlenmeleri, çocukların karşılaştığı en yaygın zehirlenme şekli olup ölümcül sonuçlar doğurabilen, ancak uygun tedbirler alınırsa önlenebilen bir durumdur. Çocuklar bir toplumun geleceğidir, bu yüzden ilaç zehirlenmesi önemli bir halk sağlığı sorunu oluşturmaktadır. Yüksek doz ilaç kombinasyonları, yanlış kullanım, kötü saklama koşulları ve çocukların ilaçlara erişimi gibi faktörlerin tümü ilaç zehirlenmesine katkıda bulunabilmektedir. Amacımız, ilaç zehirlenmesinin çocuklar üzerindeki etkisini anlamak, bu çocukların özelliklerini belirlemek ve bu sorunun önlenmesi için alınabilecek tedbirler hakkında farkındalık oluşturmaktır.
Gereç ve Yöntemler: Bu çalışma, Karabük Üniversitesi Tıp Fakültesi Eğitim ve Araştırma Hastanesi çocuk acil servisine ilaç içme ve ilaç maruziyeti şikayetiyle başvuran 100 hasta üzerinde retrospektif olarak yapılmıştır.
Bulgular: Hastaların yaş ortalamasının 7,65±6,51 yıl, %58’inin kız olduğu ve %71’inin kazayla ilaç içtiği görülmüştür. Hastaların içtiği ilaçlar incelendiğinde %18 ile en yüksek oranla analjezik-anti-İnflamatuar (Parasetemol) grubu olduğu saptanmıştır. Hastaların yatış durumları incelendiğinde %22’sinin hastaneye yatışı olmadığı görülmüştür. Hastaların %56’sının semptom yaşadığı, en çok yaşanılan semptomun %33 ile bulantı kusma olduğu görülmüştür. Hastaların hiçbirinde mortalite görülmemiştir.
Sonuç: Çalışma sonuçları çocukların sıklıkla kazayla ilaç aldıklarını göstermektedir. En çok analjezik-antipiretik grubu ilaçlar ile karşılaşılması ise, toplum içinde çok yaygın bir şekilde kullanılmasının öngörülebilen bir sonucu olduğunu düşündürmektedir. Ayrıca %78 gibi çok yüksek bir yatış oranı bulunması, ne yazıkki önlenebilecek bir durum için kısıtlı imkanlarımızın fazladan harcanmasına neden olmaktadır. Bunun için etkin bir halk sağlığı politikasının oluşturulması ve yaygın şekilde kullanılan ilaçlara yönelik önleyici tedbirlerin alınması, zehirlenmelerin sıklığını azaltabilir. Bulgularımızın, klinisyenlere yol göstereceğini düşünmekteyiz.
Anahtar Kelimeler: İlaç zehirlenmeleri, intoksikasyon, ilaç, pediatrik hastalar

References

  • 1- Alwan, I. A., Brhaish, A. S., Awadh, A. I., Misnan, A., Rahim, N. A. A., Tangiisuran, B., & Abdul Majid, M. I. Poisoning among children in Malaysia: A 10-years retrospective study. Plos one, 2022, 17.4: e0266767.
  • 2- Şenses, O., Tursun, S., & Alpcan, A. Analysis of poisoning cases admitted to the pediatric emergency department: 5 years of clinical experience. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi, 2021, 23(3), 599-606.
  • 3- Keskin, H., Kara, M., Akat, H., & Ceviz, N. Pediatric Intoxication Cases Followed in the PICU; 2-year Experience: Cocuk Yogun Bakim Unitesinde Takip Edilen Zehirlenme Olgulari; 2 Yillik Deneyim. Journal of Pediatric Emergency and Intensive Care Medicine, 2019, 6(3), 150-156.
  • 4- Ozan, E., Öztürk, S., & Çağlar, A. Retrospective Analysis of the Pediatric Intoxication Cases. Trends in pediatrics, 2022, 3(1), 10-17.
  • 5- Bulut, M., Alemdar, D. K., Bulut, A., Tekin, E., & Çelikkalkan, K. Evaluation of accidental and intentional pediatric poisoning: Retrospective analysis in an emergency Department of Turkey. Journal of Pediatric Nursing, 2022, 63, e44-e49.
  • 6- Bédard, A., Marcoux, M., Fréchette, É., & Bailey, B. Acute pediatric intoxication: A retrospective review of 511 cases. Canadian Journal of Emergency Medicine, 2020, 23(1), 40-47.
  • 7- Duyu, M., & Atış, Ş. K. Retrospective Evaluation of Intoxication Cases Followed in Pediatric Intensive Care: A 5-Year Experience. Haydarpaşa Numune Medical Journal, 2020, 60(4), 437.
  • 8- Baysal, Ş. G., & Yıldız, F. M. Çocukluk çağı zehirlenme olgularının epidemiyolojik ve demografik özelliklerinin incelenmesi. Ege Tıp Bilimleri Dergisi, 2018, 1(2), 37-42.
  • 9- Berta, G. N., Di Scipio, F., Bosetti, F. M., Mognetti, B., Romano, F., Carere, M. E., ... & Urbino, A. F. Childhood acute poisoning in the Italian North-West area: a six-year retrospective study, Italian journal of pediatrics, 2020, 46(1), 1-9.
  • 10- Soave, P. M., Curatola, A., Ferretti, S., Raitano, V., Conti, G., Gatto, A., & Chiaretti, A. Acute poisoning in children admitted to pediatric emergency department: A five-years retrospective analysis. Acta Bio Medica: Atenei Parmensis, 2022, 93(1).
  • 11- Gokalp, G. Evaluation of poisoning cases admitted to pediatric emergency department. International Journal of Pediatrics and Adolescent Medicine, 2019, 6(3), 109-114.
  • 12- Özkan, E. A. Evaluation of poisoning cases admitted to the pediatric emergency clinic retrospectively. Journal of Experimental and Clinical Medicine, 2022, 39(1), 199-203.
  • 13- Bork, T., & Kara, A. Evaluation of poisoning cases admitted to pediatric emergency department. Medicine, 2021, 10(2), 502-5.
  • 14- Tıplamaz, S., Kirkpinar, E., & Inanici, M. A. Acute poisoning in children; Evaluation of cases admitted to Marmara University Hospital in 2015. Marmara Medical Journal, 2018, 31(3), 120-125.
  • 15- Bacha, T., & Tilahun, B. A cross-sectional study of children with acute poisoning: a three-year retrospective analysis. World journal of emergency medicine, 2015, 6(4), 265.
  • 16- Ram, P., Kanchan, T., & Unnikrishnan, B. Pattern of acute poisonings in children below 15 years–a study from Mangalore, South India. Journal of forensic and legal medicine, 2014, 25, 26-29.

Evaluation of Pediatric Patients Admitted to the Hospital for Drug Intoxication

Year 2024, Volume: 11 Issue: 3, 279 - 286, 30.09.2024
https://doi.org/10.34087/cbusbed.1340460

Abstract

Abstract
Objective: Drug poisoning is the most common form of poisoning in children, and it is a situation that can lead to fatal consequences, but can be prevented if appropriate precautions are taken. Children are the future of a society, so drug poisoning poses an important public health problem. Factors such as high-dose drug combinations, misuse, poor storage conditions, and children's access to drugs can all contribute to drug intoxication. The aim of this study is to understand the effects of drug poisoning on children, to identify the characteristics of these children and to raise awareness about the measures that can be taken to prevent this problem.
Material and Methods: This study was conducted retrospectively on 100 patients who applied to the pediatric emergency department of Karabuk University Faculty of Medicine Education and Research Hospital with the complaints of drug use and drug exposure.
Results: It was observed that the mean age of the patients was 7.65±6.51 years, 58% of them were girls and 71% of them accidentally drank drugs. When the drugs consumed by the patients were examined, it was determined that the analgesic-anti-inflammatory (Paracetemol) group was the highest with 18%. When the hospitalization status of the patients was examined, it was seen that 22% of them were not hospitalized. It was observed that 56% of the patients experienced symptoms, and the most common symptom was nausea and vomiting with 33%. No mortality was observed in any of the patients.
Conclusion: Study results show that children often take drugs accidentally. The fact that analgesic-antipyretic group drugs are mostly encountered suggests that it is a predictable result of their widespread use in the community. In addition, the high hospitalization rate with 78% unfortunately leads to an extra expenditure of our limited resources for a condition that could have been prevented. For this reason, establishing an effective public health policy and taking preventive measures for commonly used drugs can reduce the frequency of poisonings. We think that our findings will guide clinicians.
Keywords: Drug poisoning, intoxication, drugs, pediatric patients

References

  • 1- Alwan, I. A., Brhaish, A. S., Awadh, A. I., Misnan, A., Rahim, N. A. A., Tangiisuran, B., & Abdul Majid, M. I. Poisoning among children in Malaysia: A 10-years retrospective study. Plos one, 2022, 17.4: e0266767.
  • 2- Şenses, O., Tursun, S., & Alpcan, A. Analysis of poisoning cases admitted to the pediatric emergency department: 5 years of clinical experience. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi, 2021, 23(3), 599-606.
  • 3- Keskin, H., Kara, M., Akat, H., & Ceviz, N. Pediatric Intoxication Cases Followed in the PICU; 2-year Experience: Cocuk Yogun Bakim Unitesinde Takip Edilen Zehirlenme Olgulari; 2 Yillik Deneyim. Journal of Pediatric Emergency and Intensive Care Medicine, 2019, 6(3), 150-156.
  • 4- Ozan, E., Öztürk, S., & Çağlar, A. Retrospective Analysis of the Pediatric Intoxication Cases. Trends in pediatrics, 2022, 3(1), 10-17.
  • 5- Bulut, M., Alemdar, D. K., Bulut, A., Tekin, E., & Çelikkalkan, K. Evaluation of accidental and intentional pediatric poisoning: Retrospective analysis in an emergency Department of Turkey. Journal of Pediatric Nursing, 2022, 63, e44-e49.
  • 6- Bédard, A., Marcoux, M., Fréchette, É., & Bailey, B. Acute pediatric intoxication: A retrospective review of 511 cases. Canadian Journal of Emergency Medicine, 2020, 23(1), 40-47.
  • 7- Duyu, M., & Atış, Ş. K. Retrospective Evaluation of Intoxication Cases Followed in Pediatric Intensive Care: A 5-Year Experience. Haydarpaşa Numune Medical Journal, 2020, 60(4), 437.
  • 8- Baysal, Ş. G., & Yıldız, F. M. Çocukluk çağı zehirlenme olgularının epidemiyolojik ve demografik özelliklerinin incelenmesi. Ege Tıp Bilimleri Dergisi, 2018, 1(2), 37-42.
  • 9- Berta, G. N., Di Scipio, F., Bosetti, F. M., Mognetti, B., Romano, F., Carere, M. E., ... & Urbino, A. F. Childhood acute poisoning in the Italian North-West area: a six-year retrospective study, Italian journal of pediatrics, 2020, 46(1), 1-9.
  • 10- Soave, P. M., Curatola, A., Ferretti, S., Raitano, V., Conti, G., Gatto, A., & Chiaretti, A. Acute poisoning in children admitted to pediatric emergency department: A five-years retrospective analysis. Acta Bio Medica: Atenei Parmensis, 2022, 93(1).
  • 11- Gokalp, G. Evaluation of poisoning cases admitted to pediatric emergency department. International Journal of Pediatrics and Adolescent Medicine, 2019, 6(3), 109-114.
  • 12- Özkan, E. A. Evaluation of poisoning cases admitted to the pediatric emergency clinic retrospectively. Journal of Experimental and Clinical Medicine, 2022, 39(1), 199-203.
  • 13- Bork, T., & Kara, A. Evaluation of poisoning cases admitted to pediatric emergency department. Medicine, 2021, 10(2), 502-5.
  • 14- Tıplamaz, S., Kirkpinar, E., & Inanici, M. A. Acute poisoning in children; Evaluation of cases admitted to Marmara University Hospital in 2015. Marmara Medical Journal, 2018, 31(3), 120-125.
  • 15- Bacha, T., & Tilahun, B. A cross-sectional study of children with acute poisoning: a three-year retrospective analysis. World journal of emergency medicine, 2015, 6(4), 265.
  • 16- Ram, P., Kanchan, T., & Unnikrishnan, B. Pattern of acute poisonings in children below 15 years–a study from Mangalore, South India. Journal of forensic and legal medicine, 2014, 25, 26-29.
There are 16 citations in total.

Details

Primary Language English
Subjects Clinical Sciences (Other)
Journal Section Araştırma Makalesi
Authors

Yusuf Deniz 0000-0003-3684-2421

Hamdi Metin 0000-0003-3110-0410

Publication Date September 30, 2024
Published in Issue Year 2024 Volume: 11 Issue: 3

Cite

APA Deniz, Y., & Metin, H. (2024). Evaluation of Pediatric Patients Admitted to the Hospital for Drug Intoxication. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, 11(3), 279-286. https://doi.org/10.34087/cbusbed.1340460
AMA Deniz Y, Metin H. Evaluation of Pediatric Patients Admitted to the Hospital for Drug Intoxication. CBU-SBED: Celal Bayar University-Health Sciences Institute Journal. September 2024;11(3):279-286. doi:10.34087/cbusbed.1340460
Chicago Deniz, Yusuf, and Hamdi Metin. “Evaluation of Pediatric Patients Admitted to the Hospital for Drug Intoxication”. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 11, no. 3 (September 2024): 279-86. https://doi.org/10.34087/cbusbed.1340460.
EndNote Deniz Y, Metin H (September 1, 2024) Evaluation of Pediatric Patients Admitted to the Hospital for Drug Intoxication. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 11 3 279–286.
IEEE Y. Deniz and H. Metin, “Evaluation of Pediatric Patients Admitted to the Hospital for Drug Intoxication”, CBU-SBED: Celal Bayar University-Health Sciences Institute Journal, vol. 11, no. 3, pp. 279–286, 2024, doi: 10.34087/cbusbed.1340460.
ISNAD Deniz, Yusuf - Metin, Hamdi. “Evaluation of Pediatric Patients Admitted to the Hospital for Drug Intoxication”. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 11/3 (September 2024), 279-286. https://doi.org/10.34087/cbusbed.1340460.
JAMA Deniz Y, Metin H. Evaluation of Pediatric Patients Admitted to the Hospital for Drug Intoxication. CBU-SBED: Celal Bayar University-Health Sciences Institute Journal. 2024;11:279–286.
MLA Deniz, Yusuf and Hamdi Metin. “Evaluation of Pediatric Patients Admitted to the Hospital for Drug Intoxication”. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, vol. 11, no. 3, 2024, pp. 279-86, doi:10.34087/cbusbed.1340460.
Vancouver Deniz Y, Metin H. Evaluation of Pediatric Patients Admitted to the Hospital for Drug Intoxication. CBU-SBED: Celal Bayar University-Health Sciences Institute Journal. 2024;11(3):279-86.