Lupus Nefritinin Klinikopatolojik Çalışması

Raouf Rahim Merza; Ayar Omer Ali; Hawar Ali Ehsan Kaka Khan

doi:10.17826/cutf.41255

EN TR

Lupus Nefritinin Klinikopatolojik Çalışması

Öz

Amaç:Lupus nefriti sistemik lupuseritematozusun en ciddi belirtilerinden biridir ve morbidite ve mortalitenin esas sebebidir. Bu çalışmanın amacı lupus nefriti olgularında erkek ve kadınlar arasında karşılaştırma yapmaktır. Materyal ve Metod:Biyopsi ile Lupus nefriti olduğu kanıtlanmış 45 hasta (32 kadın, 13 erkek) üzerinde kesitsel çalışma uygulandı. Tüm hastalara anket yapıldı. Hastalara biyokimyasal, immünolojik, serolojik, hematolojik tetkikler ve idrar tahlili yapıldı. 24 saatlik idrarda protein atılımına bakıldı. Bulgular:Yapılan çalışmaya göre kadınların (32, %71.1) erkeklere (13, %28.9) nazaran daha baskın olduğu görülmüştür. En yaygın tip olarak 4. sınıf nefriti (15, %33.3) sonrasında ise 3. sınıf nefriti (9, %20.9) görülmüştür.Sistemik lupuseritematozuslu erkek hastalar, kadınlardan daha erken bir dönemde nefriti geliştirmişlerdir.Erkeklerde daha yaygın hipertansiyon ve ödem vardı.Kadınlarda böbrek dışında en yaygın belirti mukokutanöziken erkeklerdehematolojik, kardiyovasküler, solunum ve merkezi sinir sistemi manifestasyonu görülür.Kadınlara nazaran erkeklerde daha fazla proliferatif tipte lupus nefriti gözlenmiştir. Sonuç:Erkeklerde kadınlara nazaran daha ciddi tipte lupus nefriti görülmüştür.

Anahtar Kelimeler

Sistemik lupuseritematozus,Lupus nefriti, cinsiyet

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YazışmaAdresi / Address for Correspondence: Dr.Hawar Ali Ehsan Kaka Khan Sulaimaniya General Hospital IRAQ E-mail: haekkam@gmail.com G eliştarihi/Received on : 02.04.2014
Kabul tarihi/Accepted on:30.04.2014

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Primary Language

Turkish

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Raouf Rahim Merza This is me

Ayar Omer Ali This is me

Hawar Ali Ehsan Kaka Khan This is me

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July 22, 2014

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July 22, 2014

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Year 2014 Volume: 39 Number: 4

DOI

https://doi.org/10.17826/cutf.41255

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https://izlik.org/JA67SA57AJ

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Merza, Raouf Rahim, et al. “Lupus Nefritinin Klinikopatolojik Çalışması”. Cukurova Medical Journal, vol. 39, no. 4, Dec. 2014, doi:10.17826/cutf.41255.

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Lupus Nefritinin Klinikopatolojik Çalışması

The Clinicopathological Study of Lupus Nephritis

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Lupus Nefritinin Klinikopatolojik Çalışması

Öz

Anahtar Kelimeler

References

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Primary Language

Subjects

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Submission Date

Acceptance Date

Published in Issue

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