Ostegenezis İmperfekta Olan Çocuklarda Pamidronat ve Kalsitonin Tedavilerinin Karşılaştırılması

Neslihan Önenli Mungan; Fatih Gürbüz; Eda Mengen; Özden Özgür; Ali Kemal Topaloglu; Bilgin Yüksel

EN TR

Ostegenezis İmperfekta Olan Çocuklarda Pamidronat ve Kalsitonin Tedavilerinin Karşılaştırılması

Öz

Amaç: Bu çalışmanın temel amacı osteogenezis imperfekta olan çocuklarda klinik, biyokimyasal ve radyolojik bulgular ile pamidronat ve kalsitonin tedavisinin karşılaştırılması ve pamidronat tedavisinin etkinliğinin değerlendirilmesidir. Materyal ve Metod: Yaşları 41±38 (1-120) ay arasında değişen toplam 12 hasta çalışmaya alındı. Grup 1 pamidronat tedavisine geçmeden önce 4-6 U/kg haftada üç defa intranazal kalsitonin tedavisi alan altı hasta oluşturdu. Grup 2, iki ayda bir sadece tek doz 0.5-2 mg/kg dozunda pamidronat alan altı hasta idi. Bulgular: Yıllık kırık oranları Grup 1"de 2.72 ± 0.80"den 0.40 ± 0.70"e (p

Anahtar Kelimeler

Osteogenezis imperfekta, kalsitonin, pamidronat, çocuklar

References

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Yazışma Adresi / Address for Correspondence: Dr. Fatih GÜRBÜZ Çukurova Üniversitesi Tıp Fakültesi, Çocuk Endokrinolojisi Bilim Dalı ADANA e-mail: fggurbuz@yahoo.com geliş tarihi/received :01.04.2013 kabul tarihi/accepted:25.04.2013

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Turkish

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Neslihan Önenli Mungan This is me

Fatih Gürbüz This is me

Eda Mengen This is me

Özden Özgür This is me

Ali Kemal Topaloglu This is me

Bilgin Yüksel This is me

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December 1, 2013

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July 22, 2014

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Year 2013 Volume: 38 Number: 4

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Mungan, Neslihan Önenli, et al. “Ostegenezis İmperfekta Olan Çocuklarda Pamidronat Ve Kalsitonin Tedavilerinin Karşılaştırılması”. Cukurova Medical Journal, vol. 38, no. 4, Dec. 2013, pp. 667-74, https://izlik.org/JA97MA67MP.

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Ostegenezis İmperfekta Olan Çocuklarda Pamidronat ve Kalsitonin Tedavilerinin Karşılaştırılması

Comparison of Calcitonin and Pamidronate Treatments in Children with Osteogenesis Imperfecta

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Ostegenezis İmperfekta Olan Çocuklarda Pamidronat ve Kalsitonin Tedavilerinin Karşılaştırılması

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