Effect of complications on survival after lung cancer surgery

Year 2021, , 1588 - 1595, 30.12.2021

Osman Yakşi , Ali Kılıçgün , Ezel Ersen , İsmail Sarbay , Mehmet Ünal , Akif Turna , Kamil Kaynak

https://doi.org/10.17826/cumj.980951

Cited By: 1

Abstract

Purpose: This study aims to investigate the effect of complications on survival after lung cancer surgery.
Materials and Methods: This is a retrospective study of 802 patients who underwent surgical operations for lung cancer at two centers between January 2002 and December 2019. All patients were retrospectively evaluated according to age, gender, cancer stage, surgical technique, biochemical tests, pulmonary function tests, pulmonary risk index, length of the hospital stay, and the existing number of complications.
Results: In total, 802 patients (%84 males, %16 females) with a mean age of 60 years (range 19-88 years) were included in the study. 5-year overall survival rate was 62.3%. 224 complications occurred in 180 patients (22.4%). The ten most common complications, respectively, were prolonged air leak (54), pneumonia (22), arrhythmia (19), respiratory failure (15), hemorrhage (17), atelectasis (10), pneumothorax-expansion defect (7), arrest (7) bronchopleural fistula (7), subileus-ileus (6). Cancer stage, the existing number of complications, advancing age, and tumor size are parameters that significantly affect survival. The occurs of one or more complications significantly adversely affects survival.
Conclusion: Although the morbidity and mortality of lung cancer surgery have decreased in recent years, it is still high. Advanced stage lung cancer, advancing age, enlargement of tumor size and occurs of complications that negatively affect survival. Careful preoperative preparation may play a role in increasing long-term survival, as well as preventing complications, and decreasing early mortality.

Keywords

Lung Cancer, Postoperative, Surgery, Complications

Akciğer kanseri ameliyatı sonrası gelişen komplikasyonların sağkalıma etkisi

Abstract

Amaç: Bu çalışma ile akciğer kanseri ameliyatı sonrası komplikasyon gelişiminin sağ kalıma etkisini araştırmayı amaçladık.
Gereç ve Yöntem: Ocak 2002-Aralık 2019 tarihleri arasında iki merkezde operasyon uygulanan 802 akciğer kanserli olgular geriye dönük incelendi. Hastalarda, yaş, cinsiyet, kanser evresi, ameliyat tekniği, biyokimyasal değerleri, solunum fonksiyon testleri, pulmoner risk indeksi, postoperatif yatış süreleri ve gelişen komplikasyonlar analiz edildi.
Bulgular: 802 hastanın %84 ü erkek, %16 sı kadındı. Ortalama yaş 60 (19-88yaş) idi. Genel sağkalım 5 yıllık % 62,3 idi. 180 hastada (%22.4) 224 komplikasyon gelişti. En sık görülen on komplikasyon uzamış hava kaçağı (54), pnömoni (22), aritmi (19), solunum yetmezliği (15), hemoraji (17), atelektazi (10), pnömotoraks-expansiyon kusuru (7), arrest (7), bronkoplevral fistül(7), subileus-ileus(6) olarak sıralandı. Kanser evresi, komplikasyon gelişimi, ileri yaş ve tümör çapı anlamlı olarak sağ kalımı etkileyen parametrelerdir. Bir ve/veya birden fazla komplikasyon gelişmesi sağ kalımı önemli derecede kötü etkilemektedir.
Sonuç: Akciğer kanseri cerrahisinin morbidite ve mortalitesi son yıllarda azalmakla birlikte hala yüksektir. İleri akciğer kanseri evresi, yaşın ilerlemesi, tümör çapının büyümesi ve komplikasyon gelişmesi sağkalımı olumsuz etkilemektedir. Preoperatif dikkatli hazırlık, komplikasyon gelişmesini önlemek, erken dönem mortaliteyi azaltması yanında, uzun dönemde sağkalımı artırıcı rol oynayabilir.

Keywords

Akciğer kanseri, Ameliyat sonrası, Cerrahi, komplikasyonlar

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