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İntramukozal yerleşimli taşlı yüzük hücreli mide kanserinde lenfatik metastaz

Year 2016, Volume: 41 Issue: 3, 577 - 580, 30.09.2016
https://doi.org/10.17826/cukmedj.237546

Abstract

Erken mide kanserleri lenf nodu metastazı durumuna bakılmaksızın midenin mukoza ve submukozasına sınırlı tümör olarak tanımlanmaktadır. Erken mide kanseri, mukoza tabakasına sınırlı ise, lenf nodu metastazı nadiren görülür. Taşlı yüzük hücreli histolojide ve 2 cm’den küçük intramukozal mide tümörlerinde lenf nodu metastazı daha da nadirdir. Bu yazıda mukoza tabakasına sınırlı ve lenf nodu metastazlı taşlı yüzük hücreli kanser olgusu sunulmaktadır. Mukozaya sınırlı mide tümörlerinde, taşlı yüzük hücreli histolojide, lenf nodu metastazı oranı düşük ancak olasıdır. Preoperatif evreleme araçları ile invazyon derinliğinin ve lenf nodu metastazının saptanması seçilecek cerrahi tedavi protokolünde belirleyicidir.


References

  • Murakami T. Early gastric cancer. Baltimore: University Park Press. 1971.
  • Ha TK, An JY, Youn HK, Noh JH, Sohn TS, Kim S. Indication for endoscopic mucosal resection in early signet ring cell gastric cancer. Ann Surg Oncol. 2008;15:508-13.
  • Sano T. Evaluation of the gastric cancer treatment guidelines of the Japanese Gastric Cancer Association. Gan To Kagaku Ryoho. 2010;37:582-6.
  • Papanikolaou IS, Triantafyllou M, Triantafyllou K, Rösch T. EUS in the management of gastric cancer. Ann Gastroenterol. 2011;24:9-15.
  • Edge S, Byrd DR, Compton CC, Fritz AG, Greene FL, Trotti A. AJCC Cancer Staging Manual. New York, Springer Verlag, 2010.
  • Noh SH, Hyung WJ, Cheong JH. Minimally invasive treatment for gastric cancer: approaches and selection process. J Surg Oncol. 2005;90:188-93.
  • Kwee RM, Kwee TC. Predicting lymph node status in early gastric cancer. Gastric Cancer. 2008;11:134- 48.
  • Song W, He Y, Wang S, He W, Xu J. Significance of the lymph nodes in the 7th station in rational dissection for metastasis of distal gastric cancer with different T categories. Chin J Cancer Res. 2014;26:423-30.
  • Tsendsuren T, Jun SM, Mian XH. Usefulness of endoscopic ultrasonography in preoperative TNM staging of gastric cancer. World J Gastroenterol. 2006;12:43-7.
  • Jentschura D, Heubner C, Manegold BC, Rumstadt B, Winkler M, Trede M. Surgery for early gastric cancer: a European one-center experience. World J Surg. 1997;21:845-8.
  • Takekoshi T, Baba Y, Ota H, Kato Y, Yanagisawa A, Takagi K et al. Endoscopic resection of early gastric carcinoma: results of a retrospective analysis of 308 cases. Endoscopy. 1994;26:352-8.
  • Yamamoto H, Kita H. Endoscopic therapy of early gastric cancer. Best Pract Res Clin Gastroenterol. 2005;19:909-26.
  • Kunisaki C, Shimada H, Nomura M, Matsuda G, Otsuka Y, Akiyama H. Therapeutic strategy for signet ring cell carcinoma of the stomach. Br J Surg. 2004;91:1319-24.
  • Taniuchi K, Ookawauchi K, Kumon K, Sumiyoshi T, Iwata J, Furihata M et al. Intramucosal signet ring cell gastric cancer diagnosed 15 months after the initial endoscopic examination. Case Rep Med. 2015;2015:479625.
  • Pernot S, Voron T, Perkins G, Lagorce-Pages C, Berger A, Taieb J. Signet-ring cell carcinoma of the stomach: impact on prognosis and specific therapeutic challenge. World J Gastroenterol. 2015;21:11428-38.
  • Taghavi S, Jayarajan SN, Davey A, Willis AI. Prognostic significance of signet ring gastric cancer. J Clin Oncol. 2012;30:3493-8.
  • Lee SS, Ryu SW, Kim IH, Sohn SS. Early gastric cancer with signet ring cell histology remained unresected for 53 months. J Gastric Cancer. 2011;11:189-93.
  • Lee JH, Choi IJ, Kook MC, Nam BH, Kim YW, Ryu KW. Risk factors for lymph node metastasis in patients with early gastric cancer and signet ring cell histology. Br J Surg. 2010;97:732-6.
  • Kitano S, Shiraishi N, Uyama I, Sugihara K, Tanigawa N. Japanese Laparoscopic Surgery Study Group, A multicenter study on oncologic outcome of laparoscopic gastrectomy for early cancer in Japan. Ann Surg. 2007;245:68-72.
  • Kim HM, Pak KH, Chung MJ, Cho CH, Hyung WJ, Noh SH et al.. Early gastric cancer of signet ring cell carcinoma is more amenable to endoscopic treatment than is early gastric cancer of poorly differentiated tubular adenocarcinoma in select tumor conditions. Surg Endosc. 2011;25:3087-93.
  • Wang Z, Zhang X, Hu J, Zeng W, Liang J, Zhou H, et al. Predictive factors for lymph node metastasis in early gastric cancer with signet ring cell histology and their impact on the surgical strategy: analysis of single institutional experience. J Surg Res. 2014;191:130-3.

Lymphatic metastasis of signet ring cell gastric carcinoma located on mucosa layer

Year 2016, Volume: 41 Issue: 3, 577 - 580, 30.09.2016
https://doi.org/10.17826/cukmedj.237546

Abstract

Early gastric cancer is described as tumors limited to mucosa and submucosa layers regardless of lymphatic metastasis. If early gastric cancer is limited to mucosa layer, metastasis of lymph node would be seen rarely. Further if intramucosal gastric tumors have signet ring cell histology and a size smaller than 2 cm, then lymph node metastasis are even rarer. In this paper we present a case that have signet ring cell gastric cancer limited to mucosa layer and had lymph node metastasis. It is decisive to evaluate depth of invasion and lymph node metastasis with preoperative tools to choose surgical treatment  protocol.

References

  • Murakami T. Early gastric cancer. Baltimore: University Park Press. 1971.
  • Ha TK, An JY, Youn HK, Noh JH, Sohn TS, Kim S. Indication for endoscopic mucosal resection in early signet ring cell gastric cancer. Ann Surg Oncol. 2008;15:508-13.
  • Sano T. Evaluation of the gastric cancer treatment guidelines of the Japanese Gastric Cancer Association. Gan To Kagaku Ryoho. 2010;37:582-6.
  • Papanikolaou IS, Triantafyllou M, Triantafyllou K, Rösch T. EUS in the management of gastric cancer. Ann Gastroenterol. 2011;24:9-15.
  • Edge S, Byrd DR, Compton CC, Fritz AG, Greene FL, Trotti A. AJCC Cancer Staging Manual. New York, Springer Verlag, 2010.
  • Noh SH, Hyung WJ, Cheong JH. Minimally invasive treatment for gastric cancer: approaches and selection process. J Surg Oncol. 2005;90:188-93.
  • Kwee RM, Kwee TC. Predicting lymph node status in early gastric cancer. Gastric Cancer. 2008;11:134- 48.
  • Song W, He Y, Wang S, He W, Xu J. Significance of the lymph nodes in the 7th station in rational dissection for metastasis of distal gastric cancer with different T categories. Chin J Cancer Res. 2014;26:423-30.
  • Tsendsuren T, Jun SM, Mian XH. Usefulness of endoscopic ultrasonography in preoperative TNM staging of gastric cancer. World J Gastroenterol. 2006;12:43-7.
  • Jentschura D, Heubner C, Manegold BC, Rumstadt B, Winkler M, Trede M. Surgery for early gastric cancer: a European one-center experience. World J Surg. 1997;21:845-8.
  • Takekoshi T, Baba Y, Ota H, Kato Y, Yanagisawa A, Takagi K et al. Endoscopic resection of early gastric carcinoma: results of a retrospective analysis of 308 cases. Endoscopy. 1994;26:352-8.
  • Yamamoto H, Kita H. Endoscopic therapy of early gastric cancer. Best Pract Res Clin Gastroenterol. 2005;19:909-26.
  • Kunisaki C, Shimada H, Nomura M, Matsuda G, Otsuka Y, Akiyama H. Therapeutic strategy for signet ring cell carcinoma of the stomach. Br J Surg. 2004;91:1319-24.
  • Taniuchi K, Ookawauchi K, Kumon K, Sumiyoshi T, Iwata J, Furihata M et al. Intramucosal signet ring cell gastric cancer diagnosed 15 months after the initial endoscopic examination. Case Rep Med. 2015;2015:479625.
  • Pernot S, Voron T, Perkins G, Lagorce-Pages C, Berger A, Taieb J. Signet-ring cell carcinoma of the stomach: impact on prognosis and specific therapeutic challenge. World J Gastroenterol. 2015;21:11428-38.
  • Taghavi S, Jayarajan SN, Davey A, Willis AI. Prognostic significance of signet ring gastric cancer. J Clin Oncol. 2012;30:3493-8.
  • Lee SS, Ryu SW, Kim IH, Sohn SS. Early gastric cancer with signet ring cell histology remained unresected for 53 months. J Gastric Cancer. 2011;11:189-93.
  • Lee JH, Choi IJ, Kook MC, Nam BH, Kim YW, Ryu KW. Risk factors for lymph node metastasis in patients with early gastric cancer and signet ring cell histology. Br J Surg. 2010;97:732-6.
  • Kitano S, Shiraishi N, Uyama I, Sugihara K, Tanigawa N. Japanese Laparoscopic Surgery Study Group, A multicenter study on oncologic outcome of laparoscopic gastrectomy for early cancer in Japan. Ann Surg. 2007;245:68-72.
  • Kim HM, Pak KH, Chung MJ, Cho CH, Hyung WJ, Noh SH et al.. Early gastric cancer of signet ring cell carcinoma is more amenable to endoscopic treatment than is early gastric cancer of poorly differentiated tubular adenocarcinoma in select tumor conditions. Surg Endosc. 2011;25:3087-93.
  • Wang Z, Zhang X, Hu J, Zeng W, Liang J, Zhou H, et al. Predictive factors for lymph node metastasis in early gastric cancer with signet ring cell histology and their impact on the surgical strategy: analysis of single institutional experience. J Surg Res. 2014;191:130-3.
There are 21 citations in total.

Details

Subjects Health Care Administration
Journal Section Case Report
Authors

Nidal İflazoğlu

Kıvılcım Eren Erdoğan This is me

Ali Duran This is me

Özgül Düzgün This is me

Figen Doran This is me

Cem Kaan Parsak This is me

Publication Date September 30, 2016
Published in Issue Year 2016 Volume: 41 Issue: 3

Cite

MLA İflazoğlu, Nidal et al. “Lymphatic Metastasis of Signet Ring Cell Gastric Carcinoma Located on Mucosa Layer”. Cukurova Medical Journal, vol. 41, no. 3, 2016, pp. 577-80, doi:10.17826/cukmedj.237546.