BibTex RIS Cite

Clinical features and treatment of corrosive esophagitis

Year 2016, Volume: 41 Issue: 2, 264 - 270, 30.06.2016

Abstract

Purpose: The esophageal burns caused by corrosive substances are of great importance since they progress along with serious complications. Here, we have aimed to evaluate our 39 cases we followed up and treated in our clinic due to taking in corrosive substances according to their clinical characteristics and our treatment approaches.
Materials and Methods: Thirty nine patients whose file records could be obtained and who were treated for corrosive esophagitis between January 2000 and December 2007 were included in our study. Clinical features and treatment of those cases were recorded and evaluated. 
Results: The intake rate of corrosive substances was higher in women. The amount of corrosive substance taken in was prominently higher in those having it for suicidal purposes compared to those having it by accident. According to their endoscopic features, 82.1% of the cases were found to have had endoscopic findings referred to as normal or grade 1. While ulcer grade 2-3 comprised 10.3% of all the cases, grade 4 comprised 7.7% of all the cases with severe burns.
Conclusion: To stop the oral intake, performing an endoscopic evaluation and making a treatment plan in accordance with the endoscopy results for the patients applying the clinic in the early stage due to the intake of corrosive substances are of great importance in terms of preventing the complications likely to occur.

References

  • Aksu B, İnan M. Corrosive burns of the esophagus in children. Balkan Med J. 2002;19:183-8.
  • Ökten İ. Özefagusun koroziv yanıkları. Göğüs cerrahisi. Ed: Akay H. 2. Baskı, An tıp A.Ş. Ankara. 2003:335-48.
  • Di Costanzo J, Noirclerc M, Jouglard J, Escoffier JM, Cano N, Martin J et al. New therapeutic approach to corrosive burns of the upper gastrointestinal tract. Gut. 1980;21:370-5.
  • Karaoğlu A, Önder Ö, Özütemiz Ö. Caustic ingestion injuries: evaluation of 108 cases. Turk J Gastroenterol. 1998;1:55-60.
  • Kasap E, Özütemiz Ö. Pet şişedeki tehlike: koroziv özefajit, Güncel gastroenteroloji. 2006;10:29-35.
  • Solak H. Koroziv madde ile meydana gelen özefagus striktürlerinin tedavisi. Göğüs cerrahisi. Nobel kitabevi, Konya. 1993:235-6.
  • Özçelik C, İnci İ. Özofagus yaralanmaları. Özofagus Hastalıklarının Tıbbi ve Cerrahi Tedavisi, 1. Baskı (Ed M Yüksel, A Başoğlu):77-108. İstanbul, Bilmedya Grup, 2002.
  • Einhorn A, Horton L, Altieri M, Ochsenschlager D, Klein B. Serious respiratory consequences of detergent ingestions in children. Pediatrics. 1989;84:472-4.
  • Muhlendal KEV, Oberdısse U, Krienke EG. Local injuries by accidental ingestions of corrosive substances by children. Arch Toxicol. 1978;39:299- 314.
  • Friedman EM. Caustic ingestions and foreign bodies in the aerodigestive tract of children. Pediatr Clin North Am. 1989;36:1403-10.
  • Hodgson JH. Corrosive stricture of the stomach: case report and review of literature. Br J Surg. 1959;46:358-61.
  • Koltuksuz U, Mutuş MH, Kutlu R, Özyurt H, Çetin S, Karaman A et al. Effects of caffeic acid phenethyl ester and epidermal growth factor on the development of caustic esophageal stricture in rats. J Pediatr Surg. 2001;36:1504-9.
  • Frankel EN, Waterhouse AL, Kinsella JE. Inhibition of human LDL oxidation by resveratrol. Lancet. 1993;341:1103-4.
  • Cadranel S, Scaillon M, Goyens P, P. Rodesch. Treatment of esophageal caustic injuries: experience with high-dose dexamethasone. J Pediatr Surg Int. 1993;8:97-102.
  • Liu J, Atamna H, Kuratsune H, Ames BN. Delaying brain mitochondrial decay and aging with mitochondrial antioxidants and metabolites. Ann NY Acad Sci. 2002;959:133-66.
  • Gündogdu H, Tanyel CF, Büyükpamukçu N, Hiçsönmez A. Conservative treatment of caustic esophageal strictures in children. J Pediatr Surg. 1992;27:767-70.
  • Sandgren K, Malmfors G. Ballon dilation of esophageal strictures in children. Eur J Pediatr Surg. 1998;8:9-11.
  • Evrard S, Le Moine. Self-expanding plastic stents for benign esophageal lesions. Gastrointestinal Endosc. 2004;60:894-900.
  • Kasap E, Özütemiz Ö. Pet şişedeki tehlike: koroziv özefajit. Güncel Gastroenteroloji. 2006;10:29-35.
  • Naharcı İ, Tüzün A. Kostik özefagus yaralanmaları. Güncel Gastroenteroloji. 2004:226-33.
  • Ti TK. Esophageal carcinoma associated with corrosive injury: prevention and treatment by esophageal resection. Br J Surg. 1983;70:223-5.

Koroziv özefajitin klinik özellikleri ve tedavisi

Year 2016, Volume: 41 Issue: 2, 264 - 270, 30.06.2016

Abstract

Amaç: Koroziv maddelerin oluşturdukları özofagus yanıkları ciddi komplikasyonlar ile seyrettiği için çok önemlidir. Bu çalışmada kliniğimizde takip ve tedavi ettiğimiz koroziv madde içen 39 olgumuzu klinik özellikleri ve tedavi yaklaşımlarımıza göre değerlendirmeyi amaçladık.
Gereç ve Yöntem: Çalışmamıza Ocak 2000-Aralık 2007 yılları arasında Selçuk Üniversitesi, Meram Tıp Fakültesi,Göğüs Cerrahi kliniğinde tedavi edilen ve dosya kayıtlarına ulaşılabilen 39 hasta dahil edildi. Bu hastaların klinik özellikleri ve tedavileri kaydedilerek değerlendirildi. 
Bulgular: Koroziv madde içme oranı kadınlarda daha yüksek idi. İçilen koroziv madde miktarı suisit amaçlı içenlerde yanlışlıkla içenlere oranla belirgin yüksek idi. Endoskopik özelliklerine göre olguların %82.1’inde normal veya evre 1 endoskopi bulgusuna rastlanılmıştır. Evre 2-3 ülser tüm olguların %10.3’ünü oluştururken, evre 4 ağır yanık tüm olguların %7.7’ini oluşturuyordu.
Sonuç: Koroziv madde kullanımı sonrası erken dönemde başvuran hastalarda oral alımın kesilmesi, erken evrede endoskopik değerlendirmenin yapılması ve endoskopi sonucuna göre tedavi planının yapılması komplikasyonların önlenmesi açısından büyük öneme sahiptir.

References

  • Aksu B, İnan M. Corrosive burns of the esophagus in children. Balkan Med J. 2002;19:183-8.
  • Ökten İ. Özefagusun koroziv yanıkları. Göğüs cerrahisi. Ed: Akay H. 2. Baskı, An tıp A.Ş. Ankara. 2003:335-48.
  • Di Costanzo J, Noirclerc M, Jouglard J, Escoffier JM, Cano N, Martin J et al. New therapeutic approach to corrosive burns of the upper gastrointestinal tract. Gut. 1980;21:370-5.
  • Karaoğlu A, Önder Ö, Özütemiz Ö. Caustic ingestion injuries: evaluation of 108 cases. Turk J Gastroenterol. 1998;1:55-60.
  • Kasap E, Özütemiz Ö. Pet şişedeki tehlike: koroziv özefajit, Güncel gastroenteroloji. 2006;10:29-35.
  • Solak H. Koroziv madde ile meydana gelen özefagus striktürlerinin tedavisi. Göğüs cerrahisi. Nobel kitabevi, Konya. 1993:235-6.
  • Özçelik C, İnci İ. Özofagus yaralanmaları. Özofagus Hastalıklarının Tıbbi ve Cerrahi Tedavisi, 1. Baskı (Ed M Yüksel, A Başoğlu):77-108. İstanbul, Bilmedya Grup, 2002.
  • Einhorn A, Horton L, Altieri M, Ochsenschlager D, Klein B. Serious respiratory consequences of detergent ingestions in children. Pediatrics. 1989;84:472-4.
  • Muhlendal KEV, Oberdısse U, Krienke EG. Local injuries by accidental ingestions of corrosive substances by children. Arch Toxicol. 1978;39:299- 314.
  • Friedman EM. Caustic ingestions and foreign bodies in the aerodigestive tract of children. Pediatr Clin North Am. 1989;36:1403-10.
  • Hodgson JH. Corrosive stricture of the stomach: case report and review of literature. Br J Surg. 1959;46:358-61.
  • Koltuksuz U, Mutuş MH, Kutlu R, Özyurt H, Çetin S, Karaman A et al. Effects of caffeic acid phenethyl ester and epidermal growth factor on the development of caustic esophageal stricture in rats. J Pediatr Surg. 2001;36:1504-9.
  • Frankel EN, Waterhouse AL, Kinsella JE. Inhibition of human LDL oxidation by resveratrol. Lancet. 1993;341:1103-4.
  • Cadranel S, Scaillon M, Goyens P, P. Rodesch. Treatment of esophageal caustic injuries: experience with high-dose dexamethasone. J Pediatr Surg Int. 1993;8:97-102.
  • Liu J, Atamna H, Kuratsune H, Ames BN. Delaying brain mitochondrial decay and aging with mitochondrial antioxidants and metabolites. Ann NY Acad Sci. 2002;959:133-66.
  • Gündogdu H, Tanyel CF, Büyükpamukçu N, Hiçsönmez A. Conservative treatment of caustic esophageal strictures in children. J Pediatr Surg. 1992;27:767-70.
  • Sandgren K, Malmfors G. Ballon dilation of esophageal strictures in children. Eur J Pediatr Surg. 1998;8:9-11.
  • Evrard S, Le Moine. Self-expanding plastic stents for benign esophageal lesions. Gastrointestinal Endosc. 2004;60:894-900.
  • Kasap E, Özütemiz Ö. Pet şişedeki tehlike: koroziv özefajit. Güncel Gastroenteroloji. 2006;10:29-35.
  • Naharcı İ, Tüzün A. Kostik özefagus yaralanmaları. Güncel Gastroenteroloji. 2004:226-33.
  • Ti TK. Esophageal carcinoma associated with corrosive injury: prevention and treatment by esophageal resection. Br J Surg. 1983;70:223-5.
There are 21 citations in total.

Details

Primary Language English
Journal Section Research
Authors

Bayram Metin

Olgun Arıbaş This is me

Publication Date June 30, 2016
Published in Issue Year 2016 Volume: 41 Issue: 2

Cite

MLA Metin, Bayram and Olgun Arıbaş. “Clinical Features and Treatment of Corrosive Esophagitis”. Cukurova Medical Journal, vol. 41, no. 2, 2016, pp. 264-70, doi:10.17826/cutf.204047.