Outcome of UVA-Riboflavin collagen cross-linking of cornea in patients with keratoconus

Year 2018, Volume: 43 Issue: 3, 589 - 593, 30.09.2018

Ayşe Sevgi Karadağ Burak Bilgin Nusret Özdemir

https://doi.org/10.17826/cumj.336939

Cited By: 1

Abstract

Purpose: In this study, we aimed to show changes of central corneal thickness and effects of treatment on visual acuity after corneal collagen cross-linking in keratoconus patients.

Materials and Methods: 26 eyes of 51 patients with keratoconus who undergone corneal collagen cross-linking were included in to the study. Central corneal thickness measurements and best corrected visual acuity were recorded before and after 1st and 6th month of corneal collagen cross-linking operation.

Results: Mean central corneal thickness measurements were recorded as; 435,43±44,35 μm,  376,68±66,55 μm and 392,62±64,21 μm before and after 1st and 6th month of corneal collagen cross-linking, respectively. There was a statistically significant difference between pre-op and postop 1st month, pre-op and postop 6th month and post-op 1st month and post-op 6th month central corneal thickness measurements. Also, there was a statistically significant increase in best corrected visual acuity after the operation.

Conclusion: There was a statistically significant difference between pre-op, post-op 1st month and postop 6th month central corneal thickness and best corrected visual acuity measurements.

Keywords

Keratoconus, Corneal Collagen Cross-Linking, Riboflavin, UVA

Keratokonus hastalarında UVA-Riboflavin korneal kollajen çapraz bağlama tedavisinin sonuçları

Abstract

Amaç: Bu çalışmada, keratokonus hastalarında korneal kollajen çapraz bağlama tedavisinin görme keskinliği ve merkezi kornea kalınlığına etkilerinin gösterilmesi amaçlanmıştır.

Gereç ve Yöntem: Korneal kollajen çapraz bağlama işlemi uygulanan 26 hastanın 51 gözü çalışmaya dahil edildi. Merkezi kornea kalınlık ölçümleri ve en iyi düzeltilmiş görme keskinlikleri işlemden önce ve sonrasındaki 1. ay ve 6. ayda kayıt altına alındı.

Bulgular: Ortalama merkezi kornea kalınlık ölçümleri işlem öncesi, işlem sonrası 1. ay ve işlem sonrası 6.ay olmak üzere sırasıyla 435,43±44,35μm, 376,68±66,55μm ve 392,62±64,21 μm olarak kaydedildi. İşlem öncesi ve işlem sonrası 1. ay, işlem öncesi ve işlem sonrası 6.ay ve işlem sonrası 1. ay ve işlem sonrası 6.ay merkezi kornea kalınlığı ölçümleri arasında istatistiksel olarak anlamlı fark bulundu. Aynı zamanda,  işlem sonrası görme keskinliği artışı istatistiksel olarak anlamlı bulundu.

Sonuç: İşlem öncesi, işlem sonrası 1.ay ve işlem sonrası 6. ay merkezi kornea kalınlık ölçümleri ve en iyi düzeltilmiş görme keskinliği ölçümlerinde istatistiksel olarak anlamlı değişiklikler bulundu.

Keywords

Keratokonus, Korneal kollajen çapraz bağlama, Riboflavin, UVA

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