Relationship between blood groups and anogenital wart development

Year 2019, Volume: 44 Issue: Supplement 1, 113 - 118, 29.12.2019

Murat Ozturk , İsa An

https://doi.org/10.17826/cumj.555251

Cited By: 2

Abstract

Purpose: Since the discovery of the ABO blood group, the potential role of blood groups in infectious diseases has been investigated. Some viral infections, despite viral contact, do not occur or are not symptomatic due to ABO blood groups. It is known that not all patients in contact with HPV develop clinical disease. To our knowledge, the relationship between ABO-Rh groups and anogenital wart has not been investigated previously.

Materials and Methods: 96 patients with anogenital wart and 286 sexually active patients with blood group records were included in this study. Age, sex and blood groups of the patient and control groups were retrospectively analyzed. The results were analyzed statistically.

Results: In terms of ABO blood groups, 41 (42.7%) patients had A, 21 (21.9%) patients had B, 11 (11.5%) patients had AB, 23 (23.9%) patients had 0 blood groups in the patient group. In the control group, there were 126 (44.1%) individuals A, 46 (16.1%) individuals B, 30 (10.5) individuals AB, 84 (29.3) individuals had 0 blood group.  The difference between the groups was not significant. In terms of Rh groups, 85 (88.5%) patients were Rh (+) and 11(11.5%) patients were Rh (-). In the control group, 240 (83.9%) individuals were Rh (+) and 46 (16.1%) were Rh (-). The difference between the groups was not.

Conclusion: There was no relationship between ABO-Rh groups and anogenital wart development. To clarify whether anogenital wart development is easy in some blood groups, further studies are needed in different races and geographic regions.

Keywords

genital wart, human papilloma virus, abo blood group system

Kan grupları ile anogenital siğil gelişimi arasındaki ilişki

Abstract

Amaç: ABO kan grubunun keşfedilmesinden bu yana, kan gruplarının bulaşıcı hastalıklarda potansiyel rolü araştırılmıştır. Bazı viral enfeksiyonlar, viral temasa rağmen, ABO kan grupları nedeniyle ortaya çıkmaz veya semptomatik değildir. HPV ile temas eden tüm hastaların klinik hastalık geliştirmediği bilinmektedir. Bildiğimiz kadarıyla ABO-Rh grupları ile anogenital siğil arasındaki ilişki daha önce araştırılmamıştır.

Gereç ve Yöntem: Çalışmaya anogenital siğilli 96 hasta ve kan grubu kayıtları olan 286 cinsel açıdan aktif hasta dahil edildi. Hasta ve kontrol grubunun yaş, cinsiyet ve kan grupları retrospektif olarak incelendi. Sonuçlar istatistiksel olarak analiz edildi.

Bulgular: ABO kan grupları açısından 41 (% 42.7) hastada A, 21 (%21.9) hastada B, 11 (% 11.5) hastada AB, 23 (%23.9) hastada 0 kan grubu vardı . Kontrol grubunda 126 kişi (% 44.1) A, 46 kişi (%16.1) B, 30 kişi (10.5) AB, 84 kişi (29.3) 0 kan grubuna sahipti. Gruplar arasındaki fark anlamlı değildi. Rh grupları açısından 85 (%88.5) hasta Rh (+) ve 11 (%11.5) hasta Rh (-) idi. Kontrol grubunda ise 240 (%83.9) birey Rh (+) ve 46 (%16.1) Rh (-) idi. Gruplar arasındaki fark anlamlı değildi.

Sonuç: ABO-Rh grupları ile anogenital siğil gelişimi arasında ilişki yoktu. Bazı kan gruplarında anogenital siğil gelişiminin kolay olup olmadığını netleştirmek için, farklı ırklarda ve coğrafi bölgelerde yapılacak daha fazla çalışmaya ihtiyaç vardır.

Keywords

genital siğil, insan papilloma virüsü, abo kan grubu sistemi

References

• 1. Ünal E, Gönül M, Çakmak S, et al. Serological test results of sexually transmitted diseases in patients with condyloma acuminata. Postepy Dermatol Alergo 2015;32:286-9.
• 2. Silverberg MJ, Ahdieh L, Munoz A, et al. The impact of HIV infection and immunodeficiency on human papillomavirus type 6 or 11 infection and on genital warts. Sex Transm Dis 2002;29:427-35.
• 3. Valikhani M, Kavand S, Toosi S, et al. ABO Blood groups, Rhesus factor and pemphigus. Indian J Dermatol 2007;52:176-8.
• 4. Ozyurt K, Oztürk P, Gül M, et al. ABO blood groups, Rhesus factor, and Behçet’s disease. Acta Dermatovenerol Alp Pannonica Adriat 2013;22:63-4.
• 5. Shahidi-Dadras M, Golfeshan A, Younespour S. ABO blood group antigens in patients with psoriasis and pemphigus vulgaris. Iran J Dermatol 2015;18:16-19.
• 6. Sagıroglu S, Oztarakci H, Ozturk P, et al. The association of ABO blood group and rh factor with recurrent aphthous ulceration. Ann Med Res 2018;25:540-4.
• 7. Tamega Ade A, Bezerra LV, Pereira Fde P, et al. [Blood groups and discoid lupus erythematosus]. An Bras Dermatol 2009;84:477-81.
• 8. Cooling L. Blood Groups in Infection and Host Susceptibility. Clin Microbiol Rev. 2015;28:801-70.
• 9. Mohsenpour B, Hajibagheri K, Afrasiabian S, et al. ABO blood groups and susceptibility to brucellosis. Jpn J Infect Dis 2015;68:124-7.
• 10. Donbak L, Rencuzogullari E, Topaktas M, et al. Detection of some blood group (ABO, RH-D) and serum protein (HP, a1-AT, TF) polymorphisms in Antakya Province, Turkey. Turkiye Klinikleri J Med Res 2002;20:109-113.
• 11. Mitra R, Mishra N, Rath GP. Blood groups systems. Indian J Anaesth 2014;58:524-528.
• 12. Xie J, Qureshi AA, Li Y, et al. ABO blood group and incidence of skin cancer. PLoS One 2010;5:e11972.
• 13. Terzi E, Türsen B, Dursun P, et al. The relationship between ABO blood groups and acne vulgaris. Saudi J Med Med Sci 2016; 4:26-8.
• 14. Heggelund JE, Varrot A, Imberty A, et al. Histo-blood group antigens as mediators of infections. Curr Opin Struct Biol 2017;44:190-200.
• 15. Bakhtiari S, Toosi P, Azimi S, et al. Is There a Relation between ABO Blood Groups and Clinical Outcome in Patients with Pemphigoid? A Case-Control Study. Dermatol Res Pract 2016;2016:3916750.
• 16. Harris R. Infectious diseases, the ABO blood groups and human evolution. Eugen Rev. 1963;54:201-4.
• 17. Woolf B. On estimating the relation between blood group and disease. Ann Hum Genet 1955;19:251–253.
• 18. Hutson AM, Atmar RL, Graham DY, et al. Norwalk virus infection and disease is associated with ABO histo-blood group type. J Infect Dis 2002;185:1335-7.
• 19. Young E, Roth F.J. Immunological cross-reactivity between a glycoprotein isolated from Trichophyton mentagrophytes and human isoantigen A. J.Invest.Derm. 1979;72: 46-51.
• 20. Deresinski S.C, Pappgianis D, Stevens D.A. Association of ABO blood group and outcome of coccidioidal infection. Sabouraudia 1979;17: 261-264.
• 21. Mouhari-Toure A, Saka B, Kombate K, et al. Is there an association between keloids and blood groups. ISRN Dermatol 2012;2012:750908.
• 22. Moshaverinia M, Rezazadeh F, Dalvand F, et al. The relationship between oral lichen planus and blood group antigens. World J Med Sci 2014;10:103-5.
• 23. de Giorgia V, Grazzinia M, Goria A, et al. ABO blood group and risk of cutaneous malignant melanoma. Eur J Cancer Prev 2011;20:121-122.
• 24. Macsween MP, Syme UA. ABO Blood Groups And Skin Diseases. Br J Dermatol. 1965;77:30-4.