BibTex RIS Cite

The Effect of Cigarette Smoking on Rheumatoid Arthritis.

Year 2014, Volume: 39 Issue: 4, 0 - , 22.07.2014
https://doi.org/10.17826/cutf.64445

Abstract

Purpose: To investigate the effect of smoking on rheumatoid arthritis as a causative factor, sero -positivity and activity. Materials and Methods: This case control study which is carried out in the rheumatology division of Suliamaniya teaching hospital & clinic from 15th August 2009 to 15th June 2010, Ninety_ two patients 73(79%) females and 19(21%) males who fulfilled the American College of Rheumatology diagnostic criteria for diagnosis of adult rheumatoid arthritis were included compared to 92 controls. Detail history of smoking taken and disease activity assessed according to DAS28j(Disease activity score of 28 joints). Results: All forty six smoker patients had active disease , 38(82.6%) had highly active disease according to DAS28j,these results are statistically significant (P-value =0.04), and 42(91.3%) of them had rheumatoid factor which means the positive relation between smoking and seropositivity also (P-value =0.000). Conclusion: Majority of smokers demonstrated highly active disease according to DAS28j measurement for disease activity , and the relation of smoking with seropositivity found to be positive.

References

  • MünevverSerdaro ğlu, HaşimÇakırbay, OrhanDeğer, SevilCengiz, and SibelKul . The association of antiCCP antibodies with disease activity in rheumatoid arthritis. Rheumatol Int. 2008;28:965–70.
  • Klippel JH, Stone JH, Crofford LJ, White PH. Primer on the Rheumatic Disease. 13 edition. Springer Science & Business Media, New York, USA., 2008;16-17:118-9.
  • Klareskog L, Stolt P, Lundberg K, et al. A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigensmodified by citrullination. Arthritis Rheum. 2006;54:38–46
  • Arend WP. Physiology of cytokine pathways in rheumatoid arthritis. Arthritis Rheum 2001;45:101–6.
  • J. R. Glossop, P. T. Dawes and D. L. MatteyAssociation between cigarette smoking and release of tumour necrosis factor and its soluble receptors by peripheral blood mononuclear cells in patients with rheumatoid arthritis Rheumatology. 2006;45:1223-9
  • Giorgos S Metsios, A Stavropoulos-Kalinoglou, A M Nevill, K M J Douglas, Y Koutedakisand G D Kitas. Cigarette smoking significantly increases basal metabolic rate in patients with rheumatoid arthritis Annals of the Rheumatic Diseases. 2008;67:70-3.
  • Jouni JK Jaakkola and Mika Gissler.. Maternal smoking in pregnancy as a determinant of rheumatoid arthritis and other inflammatory polyarthropathies during the first 7 years of life. International Journal of Epidemiology. 2005;34:664
  • Padyukov L, Silva C, Stolt P, Alfredsson L, Klareskog L. A gene-environment interaction between smoking and shared epitope genes in HLA-DR provides a high risk of seropositive rheumatoid arthritis. Arthritis Rheum. 2004;50:3085–92.
  • P Stolt, C Bengtsson, B Nordmark, S Lindblad, I Lundberg, L Klareskog, L Alfredsson. Quantification of the influence of cigarette smoking on rheumatoid arthritis: results from a population based case-control study, using incident cases .Ann Rheum Dis 2003;62:835-41. doi:10.1136/ard.62.9.835.
  • ZsuzsannaBaka, Edit Buzás and György Nagy. Rheumatoid arthritis and smoking: putting the pieces together.Arthritis Research & Therapy 2009,11:238 doi:1186/ar275.
  • Hutchison, L Shepstone, R Moots, JT Lear, MP Lynch. Heavy cigarette smoking is strongly associated with rheumatoid arthritis (RA), particularly in patients without a family history of RA. Annals of Rheumatic Diseases 2001;60:223-7.
  • Shirley A. Albano, Ernesto Santana-Sahagun, Michael H. Weisman Purchase Cigarette smoking and rheumatoid arthritis . Seminars in Arthritis and Rheumatis. 2001;31:146-59.
  • V. F. Manfredsdottir, T. Vikingsdottir, T. Jonsson, A. J. Geirsson, O. Kjartansson, M. Heimisdottir, S. L. Sigurdardottir, H. Valdimarsson and A. Vikingsson. The effects of tobacco smoking and rheumatoid factor seropositivity on disease activity and joint damage in early rheumatoid arthritis oxford Journal, medicine Rheumatology. 2006;45:734-40.
  • Harrison, Beverley J. MD, MRCP . Influence of cigarette smoking on disease outcome in rheumatoid arthritis.Current Opinion in Rheumatology. 2002;14:93-7.
  • Diane FeskanichScDb, Lisa A. Mandl MD, MPHc, Conclusions Karen H. Costenbader MD, MPHa,smoking Intensity, Duration, and Cessation, and the Risk of Rheumatoid Arthritis in Women. The American Journal of Medicine. 2006;119:503.
  • Söderlin MK, Petersson IF, Bergman S,Svensson B; BARFOT study groupSmoking at onset of rheumatoid arthritis (RA) and its effect on disease activity and functional status: experiences from BARFOT, a longterm observational study on early RA. Scand J Rheumatol. 2011;40:249-55.
  • Lindsey A Criswell MD, MPHa, Linda A MerlinoMScb, James R Cerhan MD, PhD, Ted R MikulsMDe, Amy S MudanoMPHe, Molly Burma MSNc, Aaron R Folsom MD, MPHf, Kenneth G SaagMDe. Cigarette smoking and the risk of rheumatoid arthritis among postmenopausal womenThe American Journal of Medicine. 2002;112:465-71.
  • Abhishek A, Butt S,Gadsby K, Zhang W, DeightonCM.Anti-TNF-alpha agents are less effective for the treatment of rheumatoid arthritis in current smokers.J Clin.Rheumatol. 2010;16:15-8.
  • Scott Baltic. Sustained RA Remission Can Be Achieved Without Biologic Drugs. Arthritis Rheum. 2009;60:2262-71.
  • AslıGençay Can, ZaferGünendi, Prognostic Factors in Rheumatoid Arthritis. Rheumatism. 2008;23:60-2.
  • Frederick Wolfe . The effect of smoking on clinical, laboratory, and radiographic status in rheumatoid arthritis.JRheumatol.2000;27:569-70.
  • Eswar Krishnan, TuulikkiSokka, PekkaHannonen. Smoking–gender interaction and risk for rheumatoid arthritis. Arthritis Res Ther 2003, 5:R158-R162.
  • Papadopoulos NG, Alamanos Y, Voulgari PV, Epagelis EK, Tsifetaki N, Drosos AA. Does cigarette smoking influence disease expression, activity and severity in early rheumatoid arthritis patients? ClinExpRheumatol.2005;23:861-6.
  • Nyhäll-Wåhlin BM, Petersson IF, Nilsson JA, Jacobsson LT, Turesson C; the BARFOT study group. High disease activity disability burden and smoking predict severe extra-articular manifestations in early rheumatoid arthritis.Rheumatology (Oxford).2009.
  • YazışmaAdresi / Address for Correspondence: Dr.Raouf Rahim Mirza Sulaimaniya University Faculty of Medicine IRAQ E-mail: raofmerza@yahoo.com. G eliştarihi/Received on :03.04.2014
  • Kabul tarihi/Accepted on: 09.04.2014

Sigaranın Romatoid Artrit Üzerine Etkileri

Year 2014, Volume: 39 Issue: 4, 0 - , 22.07.2014
https://doi.org/10.17826/cutf.64445

Abstract

Amaç:RomatoidArtrite sebep olan faktörlerden biri olan ve hastalığın seyrini ve sero-pozitivitesini etkileyen sigara kullanımının Romatoidartrit gelişimi üzerine etkilerinin incelenmesi. Materyal ve Metod: 15 08. 2009 - 15. 06. 2010 tarihleri arasında Süleymaniye Eğitim Hastanesine başvuran, Amerikan Romatoloji Kurulunun teşhis kriterlerine gore seçilen 73 kadın (%79) ve 19 erkek (%21) toplam 92 romatoit artritli olgu çalışmaya alınmıştırr. Sigara kullanan hastaların detaylı öyküleri alınarak, hastalıkgelişimi DAS28J"e (eklemlerde hastalık gelişim değeri 28) göre irdelenmiştir. Bulgular:Sigara kullanan 46 hastada ilerleyen bir romatoid artit olduğu ve 38 hastada (%82.6) DAS28J"ye göre değerlendirildiğinde, hastalığın seyrinin oldukça ilerlemiş olduğu tesbit edildi (p:0.04). 42 (%91.3) Sigara kullanımı ve seropozitivite arasında da pozitif bir ilişki olduğu belirlendi (p:0.000). Sonuç: DAS28J verilerine gore değerlendirilme yapıldığında, sigara kullananların büyük bir kısmında hastalığın ilerlemiş olduğu görüldü. Seropozitif ve sigara arasında pozitif bir ilişki bulundu.

References

  • MünevverSerdaro ğlu, HaşimÇakırbay, OrhanDeğer, SevilCengiz, and SibelKul . The association of antiCCP antibodies with disease activity in rheumatoid arthritis. Rheumatol Int. 2008;28:965–70.
  • Klippel JH, Stone JH, Crofford LJ, White PH. Primer on the Rheumatic Disease. 13 edition. Springer Science & Business Media, New York, USA., 2008;16-17:118-9.
  • Klareskog L, Stolt P, Lundberg K, et al. A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigensmodified by citrullination. Arthritis Rheum. 2006;54:38–46
  • Arend WP. Physiology of cytokine pathways in rheumatoid arthritis. Arthritis Rheum 2001;45:101–6.
  • J. R. Glossop, P. T. Dawes and D. L. MatteyAssociation between cigarette smoking and release of tumour necrosis factor and its soluble receptors by peripheral blood mononuclear cells in patients with rheumatoid arthritis Rheumatology. 2006;45:1223-9
  • Giorgos S Metsios, A Stavropoulos-Kalinoglou, A M Nevill, K M J Douglas, Y Koutedakisand G D Kitas. Cigarette smoking significantly increases basal metabolic rate in patients with rheumatoid arthritis Annals of the Rheumatic Diseases. 2008;67:70-3.
  • Jouni JK Jaakkola and Mika Gissler.. Maternal smoking in pregnancy as a determinant of rheumatoid arthritis and other inflammatory polyarthropathies during the first 7 years of life. International Journal of Epidemiology. 2005;34:664
  • Padyukov L, Silva C, Stolt P, Alfredsson L, Klareskog L. A gene-environment interaction between smoking and shared epitope genes in HLA-DR provides a high risk of seropositive rheumatoid arthritis. Arthritis Rheum. 2004;50:3085–92.
  • P Stolt, C Bengtsson, B Nordmark, S Lindblad, I Lundberg, L Klareskog, L Alfredsson. Quantification of the influence of cigarette smoking on rheumatoid arthritis: results from a population based case-control study, using incident cases .Ann Rheum Dis 2003;62:835-41. doi:10.1136/ard.62.9.835.
  • ZsuzsannaBaka, Edit Buzás and György Nagy. Rheumatoid arthritis and smoking: putting the pieces together.Arthritis Research & Therapy 2009,11:238 doi:1186/ar275.
  • Hutchison, L Shepstone, R Moots, JT Lear, MP Lynch. Heavy cigarette smoking is strongly associated with rheumatoid arthritis (RA), particularly in patients without a family history of RA. Annals of Rheumatic Diseases 2001;60:223-7.
  • Shirley A. Albano, Ernesto Santana-Sahagun, Michael H. Weisman Purchase Cigarette smoking and rheumatoid arthritis . Seminars in Arthritis and Rheumatis. 2001;31:146-59.
  • V. F. Manfredsdottir, T. Vikingsdottir, T. Jonsson, A. J. Geirsson, O. Kjartansson, M. Heimisdottir, S. L. Sigurdardottir, H. Valdimarsson and A. Vikingsson. The effects of tobacco smoking and rheumatoid factor seropositivity on disease activity and joint damage in early rheumatoid arthritis oxford Journal, medicine Rheumatology. 2006;45:734-40.
  • Harrison, Beverley J. MD, MRCP . Influence of cigarette smoking on disease outcome in rheumatoid arthritis.Current Opinion in Rheumatology. 2002;14:93-7.
  • Diane FeskanichScDb, Lisa A. Mandl MD, MPHc, Conclusions Karen H. Costenbader MD, MPHa,smoking Intensity, Duration, and Cessation, and the Risk of Rheumatoid Arthritis in Women. The American Journal of Medicine. 2006;119:503.
  • Söderlin MK, Petersson IF, Bergman S,Svensson B; BARFOT study groupSmoking at onset of rheumatoid arthritis (RA) and its effect on disease activity and functional status: experiences from BARFOT, a longterm observational study on early RA. Scand J Rheumatol. 2011;40:249-55.
  • Lindsey A Criswell MD, MPHa, Linda A MerlinoMScb, James R Cerhan MD, PhD, Ted R MikulsMDe, Amy S MudanoMPHe, Molly Burma MSNc, Aaron R Folsom MD, MPHf, Kenneth G SaagMDe. Cigarette smoking and the risk of rheumatoid arthritis among postmenopausal womenThe American Journal of Medicine. 2002;112:465-71.
  • Abhishek A, Butt S,Gadsby K, Zhang W, DeightonCM.Anti-TNF-alpha agents are less effective for the treatment of rheumatoid arthritis in current smokers.J Clin.Rheumatol. 2010;16:15-8.
  • Scott Baltic. Sustained RA Remission Can Be Achieved Without Biologic Drugs. Arthritis Rheum. 2009;60:2262-71.
  • AslıGençay Can, ZaferGünendi, Prognostic Factors in Rheumatoid Arthritis. Rheumatism. 2008;23:60-2.
  • Frederick Wolfe . The effect of smoking on clinical, laboratory, and radiographic status in rheumatoid arthritis.JRheumatol.2000;27:569-70.
  • Eswar Krishnan, TuulikkiSokka, PekkaHannonen. Smoking–gender interaction and risk for rheumatoid arthritis. Arthritis Res Ther 2003, 5:R158-R162.
  • Papadopoulos NG, Alamanos Y, Voulgari PV, Epagelis EK, Tsifetaki N, Drosos AA. Does cigarette smoking influence disease expression, activity and severity in early rheumatoid arthritis patients? ClinExpRheumatol.2005;23:861-6.
  • Nyhäll-Wåhlin BM, Petersson IF, Nilsson JA, Jacobsson LT, Turesson C; the BARFOT study group. High disease activity disability burden and smoking predict severe extra-articular manifestations in early rheumatoid arthritis.Rheumatology (Oxford).2009.
  • YazışmaAdresi / Address for Correspondence: Dr.Raouf Rahim Mirza Sulaimaniya University Faculty of Medicine IRAQ E-mail: raofmerza@yahoo.com. G eliştarihi/Received on :03.04.2014
  • Kabul tarihi/Accepted on: 09.04.2014
There are 26 citations in total.

Details

Primary Language Turkish
Journal Section Research
Authors

Raouf Rahim Mirza This is me

Publication Date July 22, 2014
Published in Issue Year 2014 Volume: 39 Issue: 4

Cite

MLA Mirza, Raouf Rahim. “Sigaranın Romatoid Artrit Üzerine Etkileri”. Cukurova Medical Journal, vol. 39, no. 4, 2014, doi:10.17826/cutf.64445.