Abstract
Creutzfeldt-Jakob disease (CJD) is a rare dementing disease and is thought to caused by a prion. It is characterized by rapidly progressive dementia, ataxia, myoclonus, akinetic mutism and eventual death. Brain biopsy or autopsy is required for a definitive diagnosis of CJD. Diffusion-weighted imaging became an important tool for early diagnosis of CJD because of the high sensitivity. We present 59-year-old female patient diagnosed as sporadic CJD with typical MR imagings.
References
- Bekiesińska-Figatowska M,Kuczyńska-Zardzewiały A,Pomianowska B,Kajdana K,Szpak GM,Iwanowska Bet al. The value of magnetic resonance imaging in the early diagnosis of Creutzfeldt-Jakob disease-own experience. Pol J Radiol.2012;77:63-7.
- Kumaran SP,Gupta K,Pushpa B,Viswamitra S,Joshy E. Diffusion-weightedimaging: As the first diagnostic clue to Creutzfeldt Jacob disease. J Neurosci Rural Pract.2012;3:408-10.
- Tschamba HJ, Zerr I, Urbach H. Radiological assessment of Creutzfeldt-Jakob disease. Eur. Radiol. 2007;17:1200-11.
- Tschampa HJ, Kallenberg K, Kretzchmar HA, Meissner B, Knauth M, Urbach H et al. Pattern of cortical changes in sporadic Creutzfekdt-Jacob disease. AJNR Am J Neuroradiol. 2007;28:1114-8. Collie DA, Summers DM, Sellar RJ, Ironside JW,Cooper S,Zeidler M et al. Diagnosing variant Creutzfeldt- Jacob disease with the pulvinar sign: MR imaging findings in 86 neuropathologically confirmed cases. AJNR Am J Neuroradiol.2003;24:1560-9.
- Kandiah N,Tan K,Pan AB,Au WL,Venketasubramanian N,Tchoyoson Lim CC et al. Creutzfeldt-Jakobdisease: which diffusion weighted imaging abnormality is associated with periodic EEG complexes? J Neurol.2008;255:1411-4.
- YazışmaAdresi / Address for Correspondence: Dr.Burak Çakır Peköz BaşkentÜniversitesiTıp Fakültesi Adana UygulamaveAraştırmaMerkezi RadyolojiAna bilim Dalı ADANA E-mail: burcakpekoz@gmail.com G eliştarihi/Received on: 01.03.2014
- Kabul tarihi/Accepted on:14.04.2014
Abstract
Creutzfeldt-Jakob hastalığı (CJH) nadir görülen progresif demansiyel bir prion hastalığıdır. Hızlı ilerleyen demans, ataksi, miyoklonus, akinetik mutizm ve sonrasında ölüm ile karakterizedir. Kesin tanıya beyin biyopsisi veya otopsi ile ulaşılabilir. Difüzyon ağırlıklı görüntüleme yüksek sensitivitesi nedeniyle CJH tanısında oldukça önemli bir tanı yöntemidir. Biz bu yazıda olası sporadik CJH tanısı konan ve tipik MR görüntüleme bulguları olan 59 yaşındaki kadın olguyu sunduk.
References
- Bekiesińska-Figatowska M,Kuczyńska-Zardzewiały A,Pomianowska B,Kajdana K,Szpak GM,Iwanowska Bet al. The value of magnetic resonance imaging in the early diagnosis of Creutzfeldt-Jakob disease-own experience. Pol J Radiol.2012;77:63-7.
- Kumaran SP,Gupta K,Pushpa B,Viswamitra S,Joshy E. Diffusion-weightedimaging: As the first diagnostic clue to Creutzfeldt Jacob disease. J Neurosci Rural Pract.2012;3:408-10.
- Tschamba HJ, Zerr I, Urbach H. Radiological assessment of Creutzfeldt-Jakob disease. Eur. Radiol. 2007;17:1200-11.
- Tschampa HJ, Kallenberg K, Kretzchmar HA, Meissner B, Knauth M, Urbach H et al. Pattern of cortical changes in sporadic Creutzfekdt-Jacob disease. AJNR Am J Neuroradiol. 2007;28:1114-8. Collie DA, Summers DM, Sellar RJ, Ironside JW,Cooper S,Zeidler M et al. Diagnosing variant Creutzfeldt- Jacob disease with the pulvinar sign: MR imaging findings in 86 neuropathologically confirmed cases. AJNR Am J Neuroradiol.2003;24:1560-9.
- Kandiah N,Tan K,Pan AB,Au WL,Venketasubramanian N,Tchoyoson Lim CC et al. Creutzfeldt-Jakobdisease: which diffusion weighted imaging abnormality is associated with periodic EEG complexes? J Neurol.2008;255:1411-4.
- YazışmaAdresi / Address for Correspondence: Dr.Burak Çakır Peköz BaşkentÜniversitesiTıp Fakültesi Adana UygulamaveAraştırmaMerkezi RadyolojiAna bilim Dalı ADANA E-mail: burcakpekoz@gmail.com G eliştarihi/Received on: 01.03.2014
- Kabul tarihi/Accepted on:14.04.2014
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Research |
| Authors | |
| Publication Date | July 22, 2014 |
| Published in Issue | Year 2014 Volume: 39 Issue: 4 |
