Prostatic melanosis is characterized by melanocytic proliferation in prostatic stroma and the epithelium. The pathogenesis of the lesion is uncertain. In literature it has been reported as a case associated with prostatic adenocarcinoma before. Primary and metastatic malignant melanoma should be considered in differantial diagnosis of the lesion
Klock C, Gomes R, João M, Netto G. Prostate Melanosis Associated With Aciner Adenoc arcinoma. Int J Surg Pathol. 2010;18:379-80
Anderco D, Lãzar Elena, Tãban S, Miclea F, Demas A. Prostatic blue nevus. 2010;51:551-7.
Nigogosyan G, Delapava S, Pickren JW, Woodruff MM. Blue nevus of the prostate gland. Cancer. 1963;16:1097-9.
Reams WM Jr. An experimental study of the development of pigment cells in the coelomic lining of the chick embryo. J Morphol. 1956;99:513-47.
Nakai J, Rappaport H. A study of the histiogenesis of experimental melenocitic tumors resembling celluler blue nevi: the evidence in support of their neurogenic origin. Am J Pathol. 1963;43:175-99.
Othuski Y, Furihata M, Sonobe H, Iwata J, Ido E, Chen B, Liang S,Ochi K. Melanosis of the prostate: an immunohistochemical study. Med Electron Microsc. 1998;31:38-41
Hameed O, Humphrey PA. Pseudoneoplastic mimics of prostate and bladder carcinomas. Arch Pathol Lab Med. 2010;134:427–43.
Brennick JB, O’Connel JX, Dickersin GR, Pilch BZ, Youngh RH. Lipofuscin pigmentation (so-called "melanosis") of the prostate. Am J Surch Pathol. 1994;18: 446-54.
Sanborn SL , MacLennan G ,. Cooney MM, Zhou M, Ponsky LM. High-grade transitional cell carcinoma and melanosis of urinary bladder: case report and review literature. Urology 73(4):928.e13-5. doi: 1016/j.urology.2008.05.039
Balaban M, Selimoglu A, Horoz R, Akca O, Albayrak S. Prostate Metastasis of Malignant Melanoma. Korean J Urol. 2013; 54:486-489
Yazışma Adresi / Address for Correspondence: Dr. Tufan Çiçek Başkent University Faculty of Medicine Department of Urology Email: tufan_ciceky@yahoo.com G eliş tarihi/Received on: 31.09.2013
Kabul tarihi/Accepted on:04.11.2013
Prostatik Melanozis: Olgu sunumu
Year 2014,
Volume: 39 Issue: 3, 602 - 605, 22.07.2014
Prostatik melanozis prostatik stroma ve epitelde melanin birikmesiyle karekterizedir. Patogenezi kesin olarak bilinmemektedir. Literatürde prostatik adenokarsinomla birlikteliği bildirilmiştir. Ürolojik açıdan primer ve metastatik melanomdan ayırımı gerekmektedir.
Klock C, Gomes R, João M, Netto G. Prostate Melanosis Associated With Aciner Adenoc arcinoma. Int J Surg Pathol. 2010;18:379-80
Anderco D, Lãzar Elena, Tãban S, Miclea F, Demas A. Prostatic blue nevus. 2010;51:551-7.
Nigogosyan G, Delapava S, Pickren JW, Woodruff MM. Blue nevus of the prostate gland. Cancer. 1963;16:1097-9.
Reams WM Jr. An experimental study of the development of pigment cells in the coelomic lining of the chick embryo. J Morphol. 1956;99:513-47.
Nakai J, Rappaport H. A study of the histiogenesis of experimental melenocitic tumors resembling celluler blue nevi: the evidence in support of their neurogenic origin. Am J Pathol. 1963;43:175-99.
Othuski Y, Furihata M, Sonobe H, Iwata J, Ido E, Chen B, Liang S,Ochi K. Melanosis of the prostate: an immunohistochemical study. Med Electron Microsc. 1998;31:38-41
Hameed O, Humphrey PA. Pseudoneoplastic mimics of prostate and bladder carcinomas. Arch Pathol Lab Med. 2010;134:427–43.
Brennick JB, O’Connel JX, Dickersin GR, Pilch BZ, Youngh RH. Lipofuscin pigmentation (so-called "melanosis") of the prostate. Am J Surch Pathol. 1994;18: 446-54.
Sanborn SL , MacLennan G ,. Cooney MM, Zhou M, Ponsky LM. High-grade transitional cell carcinoma and melanosis of urinary bladder: case report and review literature. Urology 73(4):928.e13-5. doi: 1016/j.urology.2008.05.039
Balaban M, Selimoglu A, Horoz R, Akca O, Albayrak S. Prostate Metastasis of Malignant Melanoma. Korean J Urol. 2013; 54:486-489
Yazışma Adresi / Address for Correspondence: Dr. Tufan Çiçek Başkent University Faculty of Medicine Department of Urology Email: tufan_ciceky@yahoo.com G eliş tarihi/Received on: 31.09.2013