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Autoimmune Thrombocytopenic Purpura in Hepatitis A Infection

Year 2014, Volume: 39 Issue: 3, 646 - 649, 22.07.2014
https://doi.org/10.17826/cutf.33459

Abstract

In undeveloped countries, Hepatitis A is common and endemic because of unimmunization, unhygienic nutrition and poor living conditions. Secondary immune thrombocytopenia is frequently seen in hepatitis B and C infections. It is rarely reported with acute hepatitis A. Two cases of autoimmune thrombocytopenic purpura with acute hepatitis A is presented here.

References

  • Nainan OV, Xia G, Vaughan G, Margolis HS. Diagnosis of hepatitis a virus infection: a molecular approach. Clin Microbiol Rev. 2006;19:63-79.
  • Jeong SH, Lee HS. Hepatitis A: clinical manifestations and management. Intervirology. 2010;53:15-9.
  • Schiff ER. Atypical clinical manifestations of hepatitis A. Vaccine. 1992;10:18-20.
  • Cohen O, Mevorach D, Ackerman Z, Oren R. Thrombocytopenic purpura as a manifestation of acute hepatitis A. J Clin Gastroenterol. 1993;17:166
  • Ertem D, Acar Y, Pehlivanoglu E. Autoimmune complications associated with hepatitis A virus infection in children. Pediatr Infect Dis J. 2001;20:809-11.
  • Koff RS. Clinical manifestations and diagnosis of hepatitis A virus infection. Vaccine. 1992;10:15-7.
  • Lemon SM. Type A viral hepatitis: epidemiology, diagnosis, and prevention. Clin Chem. 1997;43:1494
  • Willner IR, Uhl MD, Howard SC, Williams EQ, Riely CA, Waters B. Serious hepatitis A: an analysis of patients hospitalized during an urban epidemic in the United States. Ann Intern Med. 1998;128:111-4.
  • Maiga MY, Oberti F, Rifflet H, Ifrah N, Calès P. Hematologic manifestations related to hepatitis A virus. 3 cases. Gastroenterol Clin Biol. 1997;21:327
  • Shenoy R, Nair S, Kamath N. Thrombocytopenia in hepatitis A--an atypical presentation. Journal of tropical pediatrics. 2004;50:241-2.
  • Tanir G, Aydemir C, Tuygun N, Kaya O, Yarali N. Immune thrombocytopenic purpura as sole manifestation in a case of acute hepatitis A. Turk J Gastroenterol. 2005;16:217-9.
  • Samanta T, Das AK, Ganguly S. Profile of hepatitis A infection with atypical manifestations in children. Indian J Gastroenterol. 2010;29:31-3.
  • Yazışma Adresi / Address for Correspondence: Dr. Can Acıpayam Hatay Antakya State Hospital, Department of Pediatric Hematology and Oncology 31040 Hatay, Turkey. Tel: 90 326 219 40 00 Fax: +90 326 227 24 40
  • Email : cacipayam@hotmail.com G eliş tarihi/Received on: 26.12.2013
  • Kabul tarihi/Accepted on:29.01.2014

Hepatit A Enfeksiyonunda İmmün Trombositopenik Purpura

Year 2014, Volume: 39 Issue: 3, 646 - 649, 22.07.2014
https://doi.org/10.17826/cutf.33459

Abstract

Gelişmemiş ülkelerde, yetersiz aşılama, kötü hijyen ve yaşam koşulları nedeniyle hepatit A yaygındır. Sekonder immun trombositopeni, Hepatit B ve C enfeksiyonlarında sık görülürken, akut hepatit A enfeksiyonu bulgusu olarak nadiren bildirilmiştir. Sekonder immun trombositopenik purpurası olan akut hepatit A enfeksiyonlu 2 olgu burada sunulmuştur.

References

  • Nainan OV, Xia G, Vaughan G, Margolis HS. Diagnosis of hepatitis a virus infection: a molecular approach. Clin Microbiol Rev. 2006;19:63-79.
  • Jeong SH, Lee HS. Hepatitis A: clinical manifestations and management. Intervirology. 2010;53:15-9.
  • Schiff ER. Atypical clinical manifestations of hepatitis A. Vaccine. 1992;10:18-20.
  • Cohen O, Mevorach D, Ackerman Z, Oren R. Thrombocytopenic purpura as a manifestation of acute hepatitis A. J Clin Gastroenterol. 1993;17:166
  • Ertem D, Acar Y, Pehlivanoglu E. Autoimmune complications associated with hepatitis A virus infection in children. Pediatr Infect Dis J. 2001;20:809-11.
  • Koff RS. Clinical manifestations and diagnosis of hepatitis A virus infection. Vaccine. 1992;10:15-7.
  • Lemon SM. Type A viral hepatitis: epidemiology, diagnosis, and prevention. Clin Chem. 1997;43:1494
  • Willner IR, Uhl MD, Howard SC, Williams EQ, Riely CA, Waters B. Serious hepatitis A: an analysis of patients hospitalized during an urban epidemic in the United States. Ann Intern Med. 1998;128:111-4.
  • Maiga MY, Oberti F, Rifflet H, Ifrah N, Calès P. Hematologic manifestations related to hepatitis A virus. 3 cases. Gastroenterol Clin Biol. 1997;21:327
  • Shenoy R, Nair S, Kamath N. Thrombocytopenia in hepatitis A--an atypical presentation. Journal of tropical pediatrics. 2004;50:241-2.
  • Tanir G, Aydemir C, Tuygun N, Kaya O, Yarali N. Immune thrombocytopenic purpura as sole manifestation in a case of acute hepatitis A. Turk J Gastroenterol. 2005;16:217-9.
  • Samanta T, Das AK, Ganguly S. Profile of hepatitis A infection with atypical manifestations in children. Indian J Gastroenterol. 2010;29:31-3.
  • Yazışma Adresi / Address for Correspondence: Dr. Can Acıpayam Hatay Antakya State Hospital, Department of Pediatric Hematology and Oncology 31040 Hatay, Turkey. Tel: 90 326 219 40 00 Fax: +90 326 227 24 40
  • Email : cacipayam@hotmail.com G eliş tarihi/Received on: 26.12.2013
  • Kabul tarihi/Accepted on:29.01.2014
There are 15 citations in total.

Details

Primary Language Turkish
Journal Section Research
Authors

Can Acıpayam This is me

Sadık Kaya This is me

Özlem Sangün This is me

Gül İlhan This is me

Canan Altunay This is me

Gönül Oktay This is me

Publication Date July 22, 2014
Published in Issue Year 2014 Volume: 39 Issue: 3

Cite

MLA Acıpayam, Can et al. “Hepatit A Enfeksiyonunda İmmün Trombositopenik Purpura”. Cukurova Medical Journal, vol. 39, no. 3, 2014, pp. 646-9, doi:10.17826/cutf.33459.