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Perinatal Chicken Pox (Varicella Zoster Virus) Infection

Year 2013, Volume: 38 Issue: 2, 311 - 314, 01.06.2013

Abstract

Chickenpox is due to infection with the varicella zoster virus (VZV), a human alphaherpervirus found worldwide. Classically, the cinical disease is a febrile illness with a pruritic vesicular rash. Maternal chickenpox between 5 days before delivery to 2 days after delivery (perinatal varicella) can cause severe and even fatal illness in the newborn. A 7-day old girl baby presented on day 4 of postnatal with the complaints of widespread vesicular rash and non-suckling. Mother of the baby also had a similar eruption four day prior to delivery, which was clinically characteristic of varicella. Considering history and clinical presentation, a diagnosis of perinatal chickenpox was considered and the baby was treated with acyclovir which she responded and recovered. Herein, the clinical feasures and treatment of chickenpox infection in the perinatal period have been emphasized with this case report.

References

  • Gershon AA. Chickenpox, Measles, and Mumps. In: Remington JS, Klein JO, Wilson CB, Nizet V, Maldonado YA. Infectious Disease of the Fetus and Newborn Infant. 7nd Ed. Philadelphia. Elsevier Saunders. 2011; 89990
  • Brunell PA, Straus SE, Krause PR. Recent advances in VZV infection. Ann Intern Med. 1999; 130: 922-32.
  • Ovalı F. Yenidoğan Enfeksiyonları. 1nd Ed. İstanbul, İstanbul Medikal Yayıncılık. 2006: 327Gomella TL. Neonatology: Management, Procedures, On-Call Problems, diseases, and Drugs. 6nd Ed. United States of America: The McGraw-Hill Companies. 2009; 723-7.
  • Lamont RF, Sobel JD, Carrington D, MazakiTovi S, Kusanovic JP, Vaisbuch E, et al. Varicella-zoster virus (chickenpox) infection in pregnancy. BJOG. 2011; 118:1155-62.
  • Rizzardi E, Tagliaferro T, Snijders D, Bertuola F, Spolaore F, Monciotti CM, et al. Unilateral laryngeal paralysis in a newborn with congenital varicella syndrome. Int J Pediatr Otorhinolaryngol. 2009; 73: 115-8.
  • Gershon AA, .larussa P. Varicella-Zoster virus infections. In: Katz SL, Gershon A, Hotez PJ (Eds). Krugman's Infectious of Children. 10th Ed. Mosby-Year Book, Missouri. 1998: 620-50. Lesko SM, O'Brien KL, Schwartz B, Vezina R, Mitchell AA. Invazive group a streptococcal infection and nonsteroidal antiinflammatory drug use among children with primary varicella. Pediatrics. 2001; 107 :1108-15.
  • Mouly F, Mirlesse V, Meritet JF, Rozenberg F, Poissoiner MH, Lebon P, Daffos F. Prenatal diagnosis of fetal varicella zoster virus infection with polymerase chain reaction of amniotic fluid in 107 cases. Am J Obstet Gynecol. 1997; 177: 894

Perinatal Suçiçeği (Varisella Zoster Virüs) Enfeksiyonu

Year 2013, Volume: 38 Issue: 2, 311 - 314, 01.06.2013

Abstract

Suçiçeği, dünyada yaygın olarak bulunan bir insan alfa herpes virus olan varisella zoster virusunun neden olduğu enfeksiyondur. Kaşıntılı veziküllü lezyonlar ve ateş hastalığın klasik kliniğini oluşturmaktadır. Anne suçiçeğini doğumdan 5 gün önce veya doğumdan 2 gün sonraki dönemde geçirirse (perinatal suçiçeği) yenidoğanda ciddi hatta ölümcül hastalığa neden olabilir. 7 günlük kız bebek, 4 günlük iken başlayan vesiküler döküntü ve emmeme şikayeti ile başvurdu. Klinik olarak suçiçeği ile uyumlu olan döküntülerin bebeğin annesinde de doğumdan 4 gün önce başladığı öğrenildi. Öykü ve fizik muayene özellikleri dikkate alındığında perinatal suçiçeği tanısı konuldu ve 30mg/kg/gün asiklovir (7 gün) tedavisi verildi. Hasta tedaviye yanıt verdi ve şifa ile taburcu edildi. Yazımızda, bu olgu sunumu ile yenidoğan dönemde suçiçeğinin klinik özelliklerini ve tedavisi vurgulanmak istenmiştir.

References

  • Gershon AA. Chickenpox, Measles, and Mumps. In: Remington JS, Klein JO, Wilson CB, Nizet V, Maldonado YA. Infectious Disease of the Fetus and Newborn Infant. 7nd Ed. Philadelphia. Elsevier Saunders. 2011; 89990
  • Brunell PA, Straus SE, Krause PR. Recent advances in VZV infection. Ann Intern Med. 1999; 130: 922-32.
  • Ovalı F. Yenidoğan Enfeksiyonları. 1nd Ed. İstanbul, İstanbul Medikal Yayıncılık. 2006: 327Gomella TL. Neonatology: Management, Procedures, On-Call Problems, diseases, and Drugs. 6nd Ed. United States of America: The McGraw-Hill Companies. 2009; 723-7.
  • Lamont RF, Sobel JD, Carrington D, MazakiTovi S, Kusanovic JP, Vaisbuch E, et al. Varicella-zoster virus (chickenpox) infection in pregnancy. BJOG. 2011; 118:1155-62.
  • Rizzardi E, Tagliaferro T, Snijders D, Bertuola F, Spolaore F, Monciotti CM, et al. Unilateral laryngeal paralysis in a newborn with congenital varicella syndrome. Int J Pediatr Otorhinolaryngol. 2009; 73: 115-8.
  • Gershon AA, .larussa P. Varicella-Zoster virus infections. In: Katz SL, Gershon A, Hotez PJ (Eds). Krugman's Infectious of Children. 10th Ed. Mosby-Year Book, Missouri. 1998: 620-50. Lesko SM, O'Brien KL, Schwartz B, Vezina R, Mitchell AA. Invazive group a streptococcal infection and nonsteroidal antiinflammatory drug use among children with primary varicella. Pediatrics. 2001; 107 :1108-15.
  • Mouly F, Mirlesse V, Meritet JF, Rozenberg F, Poissoiner MH, Lebon P, Daffos F. Prenatal diagnosis of fetal varicella zoster virus infection with polymerase chain reaction of amniotic fluid in 107 cases. Am J Obstet Gynecol. 1997; 177: 894
There are 7 citations in total.

Details

Primary Language Turkish
Journal Section Research
Authors

Ali Annagür This is me

Ayhan Taştekin This is me

Pervin Günaslan This is me

Oğuzhan Demirel This is me

Ahmet Hakan Dikener This is me

Publication Date June 1, 2013
Published in Issue Year 2013 Volume: 38 Issue: 2

Cite

MLA Annagür, Ali et al. “Perinatal Suçiçeği (Varisella Zoster Virüs) Enfeksiyonu”. Cukurova Medical Journal, vol. 38, no. 2, 2013, pp. 311-4.