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A Tumefactive Multiple Sclerosis Case Mimicking a Focal Cerebral Mass

Year 2013, Volume: 38 Issue: 2, 329 - 332, 01.06.2013

Abstract

Tumefactive multiple sclerosis is a rare demyelinating disease presenting with a focal cerebral mass. Clinically and radiographically, the disease is usually difficult to differentiate from a tumor and abscess. If there is a doubt in the differential diagnosis, visual evoked potentials and CSF analysis and a trial with high dose corticosteroids should contribute to the evaluation of the patient before invasive procedures are started. Here we present a 13 year old girl with left hemiparesis, and a mass lesion on imaging studies confused with a tumor. Gross total tumor excision was performed. The pathology was consistent with a demyelinating disease.

References

  • lwamoto K, Oka H, Utsuki S, Ozawa T, Fujii K. Late-onset multiple sclerosis mimicking brain tumor: a case report. Brain Tumor Pathol. 2004; 21:83-6.
  • Renoux C, et al. Natural history of multiple sclerosis with childhood onset. N Enl J Med. 2007; 356:2603-13.
  • Ruggieri M, et al. Multiple sclerosis in children under 10 years of age. Neurol Sci. 2004; 25: 326Compston A, Confavreux C, Lassmann H et al:McAlpine's Multiple Sclerosis, 4. edition, Churchill Livingstone, China. 2006. Brunot E, Marcus JC. Multiple Sclerosis presenting as a single mass lesion. Pediatr Neurol. 1999; 20:383-6.
  • Chabas D, Gren AJ, Waubant E. Pediatric multiple sclerosis. The American Society for Experimental NeuroTherapeutics. 2006; 3:264–75.
  • Köksal V, Ekici MA, Menkü A, Bulut T, Öktem İS. Serebral tümörle karışan iki multiple skleroz olgusu. Erciyes Tıp Dergisi (Erciyes Medical Journal). 2008; 30:111-6.
  • Nilsson P. Hemicraniectomy in tumefactive demyelinating disease. European Neurological Journal; 2010; 1-9.
  • Prockop LD, Heinz ER. Demyelinating disease presenting as an intracranial mass lesion. Arch Neurol. 1965; 13:559-64.
  • Van der Velden M, Bots GT, Endtz LJ. Cranial CT in multiple sclerosisshwing a mass effect. Surg Neurol. 1979; 12:307–10.
  • Giang DW, Poduri KR, Eskin TA, et al. Multiple sclerosis masquerading as a mass lesion Neuroradiology. 1992; 34:150–4.
  • Yapici Z, Eraksoy M. Bilateral demyelinating tumefactive lesions in three children with hemiparesis. J Child Neurol. 2002;1 7:655–60.

İntrakraniyal Kitleyi Taklit Eden Tumefaktif Multipl Skleroz Olgusu

Year 2013, Volume: 38 Issue: 2, 329 - 332, 01.06.2013

Abstract

Tümefaktif multiple skleroz fokal serebral kitle olarak prezante olan nadir bir demiyelinizan hastalıktır. Klinik ve radyolojik olarak genellikle tümör veya apseden ayrımı zordur. Ayırıcı tanıda eğer şüphe varsa invazif girişimlerden önce görsel uyarılmış potansiyeller ve BOS analizi yapılması, yüksek doz kortikosteroid tedavisi denenmesi önerilmektedir. Bu yazıda sol hemiparezi ile başvuran, radyolojik olarak lezyonu kitle lezyonu olarak değerlendirilip gross total tümör eksizyonu uygulanmış ancak patoloji sonucu demiyelinizan hastalık ile uyumlu gelen 13 yaşında bir kız hasta sunulmuştur. Tümefaktif multipl skleroz, multipl skleroz, fokal serebral lezyon

References

  • lwamoto K, Oka H, Utsuki S, Ozawa T, Fujii K. Late-onset multiple sclerosis mimicking brain tumor: a case report. Brain Tumor Pathol. 2004; 21:83-6.
  • Renoux C, et al. Natural history of multiple sclerosis with childhood onset. N Enl J Med. 2007; 356:2603-13.
  • Ruggieri M, et al. Multiple sclerosis in children under 10 years of age. Neurol Sci. 2004; 25: 326Compston A, Confavreux C, Lassmann H et al:McAlpine's Multiple Sclerosis, 4. edition, Churchill Livingstone, China. 2006. Brunot E, Marcus JC. Multiple Sclerosis presenting as a single mass lesion. Pediatr Neurol. 1999; 20:383-6.
  • Chabas D, Gren AJ, Waubant E. Pediatric multiple sclerosis. The American Society for Experimental NeuroTherapeutics. 2006; 3:264–75.
  • Köksal V, Ekici MA, Menkü A, Bulut T, Öktem İS. Serebral tümörle karışan iki multiple skleroz olgusu. Erciyes Tıp Dergisi (Erciyes Medical Journal). 2008; 30:111-6.
  • Nilsson P. Hemicraniectomy in tumefactive demyelinating disease. European Neurological Journal; 2010; 1-9.
  • Prockop LD, Heinz ER. Demyelinating disease presenting as an intracranial mass lesion. Arch Neurol. 1965; 13:559-64.
  • Van der Velden M, Bots GT, Endtz LJ. Cranial CT in multiple sclerosisshwing a mass effect. Surg Neurol. 1979; 12:307–10.
  • Giang DW, Poduri KR, Eskin TA, et al. Multiple sclerosis masquerading as a mass lesion Neuroradiology. 1992; 34:150–4.
  • Yapici Z, Eraksoy M. Bilateral demyelinating tumefactive lesions in three children with hemiparesis. J Child Neurol. 2002;1 7:655–60.
There are 10 citations in total.

Details

Primary Language Turkish
Journal Section Research
Authors

Olcay Ünver This is me

Zehra İşık Hasıloğlu This is me

Umut Durak This is me

Serap Uysal This is me

Publication Date June 1, 2013
Published in Issue Year 2013 Volume: 38 Issue: 2

Cite

MLA Ünver, Olcay et al. “İntrakraniyal Kitleyi Taklit Eden Tumefaktif Multipl Skleroz Olgusu”. Cukurova Medical Journal, vol. 38, no. 2, 2013, pp. 329-32.