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Effects of Sevoflurane and Desflurane Anesthesia on Recovery and Agitation in Children Undergoing Strabismus Surgery

Year 2012, Volume: 37 Issue: 4, 186 - 192, 01.12.2012

Abstract

Purpose: We aimed to compared the effects of sevoflurane and desflurane anesthesia on recovery and early agitation in children undergoing strabismus surgery in our study. Method: Totally 42 patients undergoing elective strabismus surgery who between the ages of 2-10, ASA I-II were included this study. The patients were classified into two groups randomly. Induction of anesthesia was provided with 50% nitrous oxide, 50% oxygen and 6-8% sevoflurane in both groups. Maintenance of anesthesia was provided with sevoflurane 1-2% in Group I and desflurane 4-6% in Group II. The operation time, extubation, eye opening, obeying the verbal commands and orientation times and nausea-vomiting, laryngospasm and other adverse affects were recorded. Postoperative recovery (Modified Aldrete Emergence Score) and agitation (Pediatric Anesthesia Delirium Scale and Watcha Behaviour Scale) situation were recorded. Results: Patient"s demographic data and hemodynamic parameters were similar between the groups. Extubation, eye opening, obeying the verbal commands, orientation times were shorter in desflurane group than sevoflurane group(p< 0.05). Postoperative recovery and agitation scores were similar in two groups. Conclusion: In children, it was concluded that desflurane anesthesia may be preferred to sevoflurane because of shorter extubation, eye-opening, obeying the verbal commands and orientation times, but it did not reduce postoperative agitation.

References

  • Eckenhoff JE, Kneale DH, Dripps RD. The incidence and etiology of postanesthetic excitement. Anesthesiology. 1961; 22:667-73.
  • Vlajkovic GP, Sindjelic RP. Emergence delirium in children: Many questions, few answers. Anesth Analg. 2007; 104:84-91.
  • Weldon BC, Bell M, Craddock T. The effect of caudal analgesia on emergence agitation in children after sevoflurane versus halothane anesthesia. Anesth Analg. 2004; 98: 321-26.
  • Cohen IT, Finkel JC, Hannallah RS, Hummer KA, Patel KM. Rapid emergence does not explain agitation following sevoflurane anaesthesia in infants and children: a comparison with propofol. Paed Anaesth. 2003; 13: 63-7.
  • Davis PJ, Cohen IT, McGowen FX, Latta K. Recovery characteristics of desflurane versus halothane for maintenance of anesthesia in pediatric ambulatory patients. Anesthesiology. 1994; 80: 298- 302.
  • Van Aken H, Van Hemelrijck J, Verhaegen M. Anesthetics: total intravenous anesthesia or inhalation anesthesia in neurosurgery. Ann Fr Anesth Reanim. 1995; 14: 56-69.
  • Grundmann U, Uth M, Eichner A, Wilhelm W. Larsen R. Total intravenous anaesthesia with propofol and remifentanil in paediatric patients: a comparison with desflurane-nitrous oxide inhalation anesthesia. Acta Anaesth Scand. 1998; 42: 845-50.
  • Loop T, Priebe HJ. Recovery after anesthesia with remifentanil combined with propofol, desflurane, or sevoflurane for otorhinolaryngeal surgery. Anesth Analg. 2000; 91: 123-9.
  • Lerman J. Sevoflurane in pediatric anesthesia. Anesth Analg. 1995; 81: 4.
  • Voepel-Lewis T, Malviya S, Tait AR. A prospective cohort study of emergence agitation in the pediatric postanesthesia care unit. Anesth Analg. 2003;96:1625- 30.
  • Leopoldo Muniz da Silva, Leandro Gobbo Braz, Norma Sueli Pinheiro Módolo. J Pediatr (Rio J). 2008; 84:107-13.
  • Veyckemans F. Excitation phenomena during sevoflurane anaesthesia in children. Curr Op Anesthesiol. 2001; 14: 339-43.
  • Cohen IT, Finkel JC, Hannallah RS, Goodale DB. Clinical and biochemical effects of propofol EDTA vs sevoflurane in healthy infants and young children. Paediatr Anaesth. 2004; 14: 135-42.
  • Welborn LG, Hannallah RS, Norden JM, Ruttimann UE, Callan CM. Comparison of emergence and recovery characteristics of sevoflurane, desflurane, and halothane in pediatric ambulatory patients. Anesth Analg. 1996; 83:917-20.
  • Valley DR, Freid EB, Bailey AG, Kopp VJ, Georges LS, Fletcher J, Keifer A. Tracheal extubation of deeply anesthetized pediatric patients: a comparison of desflurane and sevoflurane. Anesth Analg. 2003; 96: 1320-24.
  • Uzun S, Tuncer S, Tavlan A, Reisli R, Şarkılar G, Ökeşli anestezisinin idame ve derlenme üzerine olan etkilerinin karşılaştırılması. Anest Rean Cem Mec. 2003; 31: 415-21.
  • desfluran-sevofluran
  • Goeters C, Van Aken H. Why the new inhalation agents? Eur J Anesthesiol. 1999; 16: 583-4.
  • Tarazi ME, Philip BK. A comparison of recovery after sevoflurane or desflurane in ambulatory anesthesia. J Clinic Anesth. 1998; 10: 272-7.
  • Behne M, Wilke H, Lischke V. Recovery and pharmacokinetic parameters of desflurane, sevoflurane and isoflurane in patients undergoing urologic procedures. J Clin Anesth. 1999; 11: 460-5.
  • Sun R, Watcha MF, White PF, Skrivanek GD, Griffin JD, Stool L, Murphy MT. A cost comparison of methohexital and propofol for ambulatory anesthesia. Anesth Analg. 1999; 89: 311-6.
  • Eshima RW, Maurer A, King T, Lin B, Heavner JE, Bogetz MS, Kaye AD. A comparison of airway responses during desflurane and sevoflurane administration via laryngeal mask airway for maintenance of anesthesia. Anesth Analg. 2003; 96: 701-5.
  • White PF, Tang J, Wender RH, Yumul R, Stokes OJ, Sloninsky A, et al. Desflurane versus sevoflurane for maintenance of outpatient anesthesia: the effect on early versus late recovery and perioperative coughing. Anesth Analg. 2009; 109: 387-93.
  • Naidu-Sjöswärd K, Sjöberg F, Gupta A. Anaesthesia for videoarthroscopy of the knee a comparison between desflurane and sevoflurane. Acta 31. Gergin S, Çevik B, Yıldırım GB, Çıplakgil E, Anesthesiol Scand. 1998; 42 464-71.
  • Gupta A, Stierer T, Zuckerman R, Sakima N, Parker SD, Fleisher LA. Comparison of recovery profile after ambulatory anesthesia with propofol, izoflurane, sevoflurane and desflurane: asystemic review. Anesth Analg. 2004; 98: 632-41.
  • Eshima RW, Large MJC, Balea MC, McKay WR. Airway reflexes return more rapidly after desflurane anesthesia than after sevoflurane anesthesia. Anesth analg. 2005; 100: 697-700.
  • Coloma M, Zhou T, White FP, Markowitz SD, Forestner JE. Fast-Tracking after outpatient laparoscopy: reasons for failure after propofol, sevoflurane and desflurane anesthesia. Anesth Analg. 2001; 93: 112-5.
  • Işık Y, Göksu S, Koçoğlu H, Öner U. Low flow desflurane and sevoflurane anaesthesia in children. Eur J Anaesthesiol. 2006; 23: 60-4.
  • Mayer J, Boldt J, Rohm KD, Scheuermann K, Suttner SW. Desflurane anesthesia after sevoflurane inhaled induction reduces severity of emergence agitation in children undergoing minor ear-nose- throat surgery compared with sevoflurane induction and maintenance. Anesth Analg. 2006; 102: 400-4.
  • Özgültekin A, Turan G, Doğramacı YG, Çelik H, Akgün N. Çocuklarda günübirlik anestezisinde sevofluran, desfluran ve propofol- remifentanil (TIVA) uygulamalarında derlenme özellikleri. Türkiye Klinikleri J. Anest Reanim. 2007; 5: 57-63.
  • Tercan E, Kotanoğlu MS, Yıldız K, Doğru K, Boyacı A. Comparison of recovery properties of desflurane and sevoflurane according to gender differences. Acta Anaesthesiol Scand. 2005; 49: 243-7. Çolakoğlu Haemodynamic Parameters and Recovery Characteristics. The Internet Journal of Anesthesiology. 2005; 9: 1092-406.
  • Nathanson MH, Fredman B, Smith I, White PF. Sevoflurane versus desflurane for outpatient anesthesia: a comparison of maintenance and recovery profiles. Anesth Analg. 1995; 81: 1186-90.
  • Jellish WS, Owen K, Edelstein S, Fluder E, Leonetti JP. Standard anesthetic technique for middle ear surgical procedures: a comparison of desflurane and sevoflurane. Otolaryngol Head Neck Surg. 2005; 133: 269-74.
  • Song D, Joshi GP, White PF. Fast-track eligibility after ambulatory anesthesia: A comparison of desflurane, sevoflurane and propofol. Anesth Analg. 1998; 86: 267-73.
  • Rampill IJ, Lockhart HS, Zwass MS, Peterson N, Yasuda N, Eger EI 2nd, Weiskopf RB, Damask MC. Clinical characteristics of desflurane in surgical patients minimum alveolar concentration. Anesthesiology. 1991; 74: 429-33.
  • Zwass SM, Fisher DM, Welborn LG, Coté CJ, Davis PJ, Dinner M, et al. Induction and maintenance characteristics of anesthesia with desflurane and nitrous oxide in infants and children. Anesthesiology. 1992; 76: 373-8.
  • Hemelrijick JV, Smith I, White PF. Use of desflurane for outpatient anesthesia. A comparison with propofol and nitrous oxide. Anesthesiology. 1991; 75: 197- 203.

Çocuklarda Şaşılık Cerrahisinde Sevofluran ve Desfluran Anestezisinin Derlenme ve Ajitasyon Üzerine Etkileri

Year 2012, Volume: 37 Issue: 4, 186 - 192, 01.12.2012

Abstract

Amaç: Çalışmamızda şaşılık cerrahisi uygulanan çocuklarda sevofluran ve desfluran anestezisinin derlenme ve erken ajitasyon üzerine etkilerini karşılaştırmayı amaçladık. Yöntem: Çalışmaya elektif şaşılık cerrahisi uygulanacak ASA I-II grubu, 2-10 yaşları arasında 42 hasta (kız=21, erkek=21) alındı. Hastalar rastgele 2 gruba ayrıldı. Anestezi indüksiyonu her iki grupta % 6-8 sevofluran, % 50 azot protoksit ve % 50 oksijen ile sağlandı. Anestezi idamesi I. Grupta % 1-2 sevofluran, II. Grupta ise % 4-6 desfluran ile idame ettirildi. Operasyon süresi, ekstübasyon, göz açma, uyarılara riayet ve oryantasyon süreleri ile laringospazm, bulantı kusma ve diğer yan etkiler kaydedildi. Her iki grubun postoperatif derlenme (Modifiye Aldrete Derlenme Skoru) ve ajitasyon durumu (Pediatrik Anestezi Deliryum Skalası ve Watcha Davranış Skalası) kaydedildi. Bulgular: Grupların demografik verileri ve hemodinamik parametreleri birbirine benzerdi. Desfluran grubunda ekstübasyon, göz açma, uyarılara riayet ve oryantasyon süreleri sevofluran grubundan daha kısa bulundu (p

References

  • Eckenhoff JE, Kneale DH, Dripps RD. The incidence and etiology of postanesthetic excitement. Anesthesiology. 1961; 22:667-73.
  • Vlajkovic GP, Sindjelic RP. Emergence delirium in children: Many questions, few answers. Anesth Analg. 2007; 104:84-91.
  • Weldon BC, Bell M, Craddock T. The effect of caudal analgesia on emergence agitation in children after sevoflurane versus halothane anesthesia. Anesth Analg. 2004; 98: 321-26.
  • Cohen IT, Finkel JC, Hannallah RS, Hummer KA, Patel KM. Rapid emergence does not explain agitation following sevoflurane anaesthesia in infants and children: a comparison with propofol. Paed Anaesth. 2003; 13: 63-7.
  • Davis PJ, Cohen IT, McGowen FX, Latta K. Recovery characteristics of desflurane versus halothane for maintenance of anesthesia in pediatric ambulatory patients. Anesthesiology. 1994; 80: 298- 302.
  • Van Aken H, Van Hemelrijck J, Verhaegen M. Anesthetics: total intravenous anesthesia or inhalation anesthesia in neurosurgery. Ann Fr Anesth Reanim. 1995; 14: 56-69.
  • Grundmann U, Uth M, Eichner A, Wilhelm W. Larsen R. Total intravenous anaesthesia with propofol and remifentanil in paediatric patients: a comparison with desflurane-nitrous oxide inhalation anesthesia. Acta Anaesth Scand. 1998; 42: 845-50.
  • Loop T, Priebe HJ. Recovery after anesthesia with remifentanil combined with propofol, desflurane, or sevoflurane for otorhinolaryngeal surgery. Anesth Analg. 2000; 91: 123-9.
  • Lerman J. Sevoflurane in pediatric anesthesia. Anesth Analg. 1995; 81: 4.
  • Voepel-Lewis T, Malviya S, Tait AR. A prospective cohort study of emergence agitation in the pediatric postanesthesia care unit. Anesth Analg. 2003;96:1625- 30.
  • Leopoldo Muniz da Silva, Leandro Gobbo Braz, Norma Sueli Pinheiro Módolo. J Pediatr (Rio J). 2008; 84:107-13.
  • Veyckemans F. Excitation phenomena during sevoflurane anaesthesia in children. Curr Op Anesthesiol. 2001; 14: 339-43.
  • Cohen IT, Finkel JC, Hannallah RS, Goodale DB. Clinical and biochemical effects of propofol EDTA vs sevoflurane in healthy infants and young children. Paediatr Anaesth. 2004; 14: 135-42.
  • Welborn LG, Hannallah RS, Norden JM, Ruttimann UE, Callan CM. Comparison of emergence and recovery characteristics of sevoflurane, desflurane, and halothane in pediatric ambulatory patients. Anesth Analg. 1996; 83:917-20.
  • Valley DR, Freid EB, Bailey AG, Kopp VJ, Georges LS, Fletcher J, Keifer A. Tracheal extubation of deeply anesthetized pediatric patients: a comparison of desflurane and sevoflurane. Anesth Analg. 2003; 96: 1320-24.
  • Uzun S, Tuncer S, Tavlan A, Reisli R, Şarkılar G, Ökeşli anestezisinin idame ve derlenme üzerine olan etkilerinin karşılaştırılması. Anest Rean Cem Mec. 2003; 31: 415-21.
  • desfluran-sevofluran
  • Goeters C, Van Aken H. Why the new inhalation agents? Eur J Anesthesiol. 1999; 16: 583-4.
  • Tarazi ME, Philip BK. A comparison of recovery after sevoflurane or desflurane in ambulatory anesthesia. J Clinic Anesth. 1998; 10: 272-7.
  • Behne M, Wilke H, Lischke V. Recovery and pharmacokinetic parameters of desflurane, sevoflurane and isoflurane in patients undergoing urologic procedures. J Clin Anesth. 1999; 11: 460-5.
  • Sun R, Watcha MF, White PF, Skrivanek GD, Griffin JD, Stool L, Murphy MT. A cost comparison of methohexital and propofol for ambulatory anesthesia. Anesth Analg. 1999; 89: 311-6.
  • Eshima RW, Maurer A, King T, Lin B, Heavner JE, Bogetz MS, Kaye AD. A comparison of airway responses during desflurane and sevoflurane administration via laryngeal mask airway for maintenance of anesthesia. Anesth Analg. 2003; 96: 701-5.
  • White PF, Tang J, Wender RH, Yumul R, Stokes OJ, Sloninsky A, et al. Desflurane versus sevoflurane for maintenance of outpatient anesthesia: the effect on early versus late recovery and perioperative coughing. Anesth Analg. 2009; 109: 387-93.
  • Naidu-Sjöswärd K, Sjöberg F, Gupta A. Anaesthesia for videoarthroscopy of the knee a comparison between desflurane and sevoflurane. Acta 31. Gergin S, Çevik B, Yıldırım GB, Çıplakgil E, Anesthesiol Scand. 1998; 42 464-71.
  • Gupta A, Stierer T, Zuckerman R, Sakima N, Parker SD, Fleisher LA. Comparison of recovery profile after ambulatory anesthesia with propofol, izoflurane, sevoflurane and desflurane: asystemic review. Anesth Analg. 2004; 98: 632-41.
  • Eshima RW, Large MJC, Balea MC, McKay WR. Airway reflexes return more rapidly after desflurane anesthesia than after sevoflurane anesthesia. Anesth analg. 2005; 100: 697-700.
  • Coloma M, Zhou T, White FP, Markowitz SD, Forestner JE. Fast-Tracking after outpatient laparoscopy: reasons for failure after propofol, sevoflurane and desflurane anesthesia. Anesth Analg. 2001; 93: 112-5.
  • Işık Y, Göksu S, Koçoğlu H, Öner U. Low flow desflurane and sevoflurane anaesthesia in children. Eur J Anaesthesiol. 2006; 23: 60-4.
  • Mayer J, Boldt J, Rohm KD, Scheuermann K, Suttner SW. Desflurane anesthesia after sevoflurane inhaled induction reduces severity of emergence agitation in children undergoing minor ear-nose- throat surgery compared with sevoflurane induction and maintenance. Anesth Analg. 2006; 102: 400-4.
  • Özgültekin A, Turan G, Doğramacı YG, Çelik H, Akgün N. Çocuklarda günübirlik anestezisinde sevofluran, desfluran ve propofol- remifentanil (TIVA) uygulamalarında derlenme özellikleri. Türkiye Klinikleri J. Anest Reanim. 2007; 5: 57-63.
  • Tercan E, Kotanoğlu MS, Yıldız K, Doğru K, Boyacı A. Comparison of recovery properties of desflurane and sevoflurane according to gender differences. Acta Anaesthesiol Scand. 2005; 49: 243-7. Çolakoğlu Haemodynamic Parameters and Recovery Characteristics. The Internet Journal of Anesthesiology. 2005; 9: 1092-406.
  • Nathanson MH, Fredman B, Smith I, White PF. Sevoflurane versus desflurane for outpatient anesthesia: a comparison of maintenance and recovery profiles. Anesth Analg. 1995; 81: 1186-90.
  • Jellish WS, Owen K, Edelstein S, Fluder E, Leonetti JP. Standard anesthetic technique for middle ear surgical procedures: a comparison of desflurane and sevoflurane. Otolaryngol Head Neck Surg. 2005; 133: 269-74.
  • Song D, Joshi GP, White PF. Fast-track eligibility after ambulatory anesthesia: A comparison of desflurane, sevoflurane and propofol. Anesth Analg. 1998; 86: 267-73.
  • Rampill IJ, Lockhart HS, Zwass MS, Peterson N, Yasuda N, Eger EI 2nd, Weiskopf RB, Damask MC. Clinical characteristics of desflurane in surgical patients minimum alveolar concentration. Anesthesiology. 1991; 74: 429-33.
  • Zwass SM, Fisher DM, Welborn LG, Coté CJ, Davis PJ, Dinner M, et al. Induction and maintenance characteristics of anesthesia with desflurane and nitrous oxide in infants and children. Anesthesiology. 1992; 76: 373-8.
  • Hemelrijick JV, Smith I, White PF. Use of desflurane for outpatient anesthesia. A comparison with propofol and nitrous oxide. Anesthesiology. 1991; 75: 197- 203.
There are 37 citations in total.

Details

Primary Language Turkish
Journal Section Research
Authors

Meziyet Saraç Ahrazoğlu This is me

Mediha Türktan This is me

Hayri Özbek This is me

Yasemin Güneş This is me

Publication Date December 1, 2012
Published in Issue Year 2012 Volume: 37 Issue: 4

Cite

MLA Ahrazoğlu, Meziyet Saraç et al. “Çocuklarda Şaşılık Cerrahisinde Sevofluran Ve Desfluran Anestezisinin Derlenme Ve Ajitasyon Üzerine Etkileri”. Cukurova Medical Journal, vol. 37, no. 4, 2012, pp. 186-92.